prednisone-4400 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the prednisone-4400 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAMDC adipogenesis associated, Mth938 domain containing
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4
AGFG1 ArfGAP with FG repeats 1
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARHGAP26 Rho GTPase activating protein 26
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BMP10 bone morphogenetic protein 10
CA14 carbonic anhydrase XIV
CEP41 centrosomal protein 41kDa
CPEB3 cytoplasmic polyadenylation element binding protein 3
CREBBP CREB binding protein
CTNS cystinosin, lysosomal cystine transporter
DCBLD2 discoidin, CUB and LCCL domain containing 2
DIO2 deiodinase, iodothyronine, type II
E2F5 E2F transcription factor 5, p130-binding
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
ELAVL2 ELAV like neuron-specific RNA binding protein 2
FGF16 fibroblast growth factor 16
FRY furry homolog (Drosophila)
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2
GEMIN7 gem (nuclear organelle) associated protein 7
GFI1 growth factor independent 1 transcription repressor
GLS glutaminase
GPATCH4 G patch domain containing 4
GRSF1 G-rich RNA sequence binding factor 1
GSTM5 glutathione S-transferase mu 5
HAS1 hyaluronan synthase 1
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HNF4A hepatocyte nuclear factor 4, alpha
HOXA1 homeobox A1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IL36R interleukin 36 receptor
INE1 inactivation escape 1 (non-protein coding)
ING2 inhibitor of growth family, member 2
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KLF13 Kruppel-like factor 13
LAMA2 laminin, alpha 2
LOC100286895 cell division cycle 27 homolog pseudogene
LRRC17 leucine rich repeat containing 17
MC5R melanocortin 5 receptor
MED25 mediator complex subunit 25
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP11 matrix metallopeptidase 11
MX1 MX dynamin-like GTPase 1
NCKAP1 NCK-associated protein 1
NEU3 sialidase 3 (membrane sialidase)
NID1 nidogen 1
NKX2-8 NK2 homeobox 8
NNAT neuronatin
NUP188 nucleoporin 188kDa
OLFM1 olfactomedin 1
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OR3A3 olfactory receptor, family 3, subfamily A, member 3
OR7E24 olfactory receptor, family 7, subfamily E, member 24
OSGIN2 oxidative stress induced growth inhibitor family member 2
PARVB parvin, beta
PCDHA9 protocadherin alpha 9
PCDHGA8 protocadherin gamma subfamily A, 8
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDE4DIP phosphodiesterase 4D interacting protein
PGK1 phosphoglycerate kinase 1
PLCL2 phospholipase C-like 2
PLLP plasmolipin
PMCH pro-melanin-concentrating hormone
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRELP proline/arginine-rich end leucine-rich repeat protein
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
RAB2A RAB2A, member RAS oncogene family
RAB6B RAB6B, member RAS oncogene family
RPAIN RPA interacting protein
RPLP2 ribosomal protein, large, P2
RPS4Y1 ribosomal protein S4, Y-linked 1
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SAP30 Sin3A-associated protein, 30kDa
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SMC1A structural maintenance of chromosomes 1A
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SOX21 SRY (sex determining region Y)-box 21
STAB2 stabilin 2
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TECPR2 tectonin beta-propeller repeat containing 2
TEX14 testis expressed 14
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TM4SF5 transmembrane 4 L six family member 5
TNPO2 transportin 2
TYRP1 tyrosinase-related protein 1
UTF1 undifferentiated embryonic cell transcription factor 1
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VDAC3 voltage-dependent anion channel 3
XYLB xylulokinase homolog (H. influenzae)
ZBTB17 zinc finger and BTB domain containing 17
ZFP2 ZFP2 zinc finger protein

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ADAM2 ADAM metallopeptidase domain 2
ADTRP androgen-dependent TFPI-regulating protein
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
AOC2 amine oxidase, copper containing 2 (retina-specific)
APLP1 amyloid beta (A4) precursor-like protein 1
ARMC4 armadillo repeat containing 4
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
BTF3P11 basic transcription factor 3 pseudogene 11
C11ORF30 chromosome 11 open reading frame 30
C17ORF70 chromosome 17 open reading frame 70
CD3D CD3d molecule, delta (CD3-TCR complex)
CDADC1 cytidine and dCMP deaminase domain containing 1
CDHR2 cadherin-related family member 2
CLSTN2 calsyntenin 2
CNTNAP1 contactin associated protein 1
CPNE7 copine VII
CRIP1 cysteine-rich protein 1 (intestinal)
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DGKQ diacylglycerol kinase, theta 110kDa
DLK2 delta-like 2 homolog (Drosophila)
DSC3 desmocollin 3
DSCAM Down syndrome cell adhesion molecule
EMID1 EMI domain containing 1
ERCC2 excision repair cross-complementation group 2
ERCC6 excision repair cross-complementation group 6
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOC6B exocyst complex component 6B
FLJ21369 uncharacterized protein FLJ21369
FOXI1 forkhead box I1
FRS2 fibroblast growth factor receptor substrate 2
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GJA9 gap junction protein, alpha 9, 59kDa
GK2 glycerol kinase 2
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPC3 glypican 3
GPR176 G protein-coupled receptor 176
GPR27 G protein-coupled receptor 27
GSTT1 glutathione S-transferase theta 1
HDAC7 histone deacetylase 7
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HOXB2 homeobox B2
HOXC8 homeobox C8
IFI27 interferon, alpha-inducible protein 27
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IFT54 intraflagellar transport 54
IL2 interleukin 2
IRF9 interferon regulatory factor 9
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KDM8 lysine (K)-specific demethylase 8
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF2 Kruppel-like factor 2
KLF7 Kruppel-like factor 7 (ubiquitous)
KRT24 keratin 24, type I
LMNB1 lamin B1
LPPR1 lipid phosphate phosphatase-related protein type 1
LY6D lymphocyte antigen 6 complex, locus D
LY6G6C lymphocyte antigen 6 complex, locus G6C
MCOLN3 mucolipin 3
MSI1 musashi RNA-binding protein 1
MUC6 mucin 6, oligomeric mucus/gel-forming
MX2 MX dynamin-like GTPase 2
NACA2 nascent polypeptide-associated complex alpha subunit 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
PCDHB13 protocadherin beta 13
PLA2G3 phospholipase A2, group III
PLEKHA6 pleckstrin homology domain containing, family A member 6
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
S100A9 S100 calcium binding protein A9
SCN1B sodium channel, voltage gated, type I beta subunit
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPINK5 serine peptidase inhibitor, Kazal type 5
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
STAG3 stromal antigen 3
STRA6 stimulated by retinoic acid 6
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TCEAL2 transcription elongation factor A (SII)-like 2
THRB thyroid hormone receptor, beta
TMEM209 transmembrane protein 209
TMEM8B transmembrane protein 8B
TPSG1 tryptase gamma 1
TRPC5 transient receptor potential cation channel, subfamily C, member 5
VIM vimentin
VIPR1 vasoactive intestinal peptide receptor 1
WDR33 WD repeat domain 33
ZBTB22 zinc finger and BTB domain containing 22
ZNF747 zinc finger protein 747
ZSWIM1 zinc finger, SWIM-type containing 1