A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics. (Gene Ontology, GO_0016272)
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9 proteins localized to the prefoldin complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.