prefoldin complex Gene Set

Dataset GO Cellular Component Annotations 2015
Category structural or functional annotations
Type cellular component
Description A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics. (Gene Ontology, GO_0016272)
External Link http://amigo.geneontology.org/amigo/term/GO:0016272
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Genes

7 proteins localized to the prefoldin complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.

Symbol Name
PDRG1 p53 and DNA-damage regulated 1
PFDN1 prefoldin subunit 1
PFDN2 prefoldin subunit 2
PFDN4 prefoldin subunit 4
PFDN5 prefoldin subunit 5
PFDN6 prefoldin subunit 6
VBP1 von Hippel-Lindau binding protein 1