| Dataset | GO Cellular Component Annotations 2015 |
| Category | structural or functional annotations |
| Type | cellular component |
| Description | A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics. (Gene Ontology, GO_0016272) |
| External Link | http://amigo.geneontology.org/amigo/term/GO:0016272 |
| Similar Terms | |
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7 proteins localized to the prefoldin complex cellular component from the curated GO Cellular Component Annotations 2015 dataset.