| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the pregnenolone-2497 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ABLIM1 | actin binding LIM protein 1 |
| ACAN | aggrecan |
| ACPP | acid phosphatase, prostate |
| ADCY2 | adenylate cyclase 2 (brain) |
| ADCY9 | adenylate cyclase 9 |
| ADGRE3 | adhesion G protein-coupled receptor E3 |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| AQP4 | aquaporin 4 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATP13A2 | ATPase type 13A2 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| BAIAP2 | BAI1-associated protein 2 |
| BEGAIN | brain-enriched guanylate kinase-associated |
| BIN1 | bridging integrator 1 |
| C1QL1 | complement component 1, q subcomponent-like 1 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CALCR | calcitonin receptor |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CDK5R1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CFAP45 | cilia and flagella associated protein 45 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CLEC4E | C-type lectin domain family 4, member E |
| CNPY4 | canopy FGF signaling regulator 4 |
| COL10A1 | collagen, type X, alpha 1 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| DAG1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) |
| DICER1 | dicer 1, ribonuclease type III |
| DIO2 | deiodinase, iodothyronine, type II |
| F2R | coagulation factor II (thrombin) receptor |
| FAM149A | family with sequence similarity 149, member A |
| FBXO22 | F-box protein 22 |
| FCAR | Fc fragment of IgA receptor |
| GFOD2 | glucose-fructose oxidoreductase domain containing 2 |
| GH1 | growth hormone 1 |
| GPM6A | glycoprotein M6A |
| GPR22 | G protein-coupled receptor 22 |
| GRAP | GRB2-related adaptor protein |
| HFE | hemochromatosis |
| HOXA4 | homeobox A4 |
| HR | hair growth associated |
| IL10 | interleukin 10 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA0513 | KIAA0513 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LIG3 | ligase III, DNA, ATP-dependent |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LMOD1 | leiomodin 1 (smooth muscle) |
| MAPT | microtubule-associated protein tau |
| MLF1 | myeloid leukemia factor 1 |
| MRPS12 | mitochondrial ribosomal protein S12 |
| NOV | nephroblastoma overexpressed |
| NUP50 | nucleoporin 50kDa |
| NUP88 | nucleoporin 88kDa |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PODNL1 | podocan-like 1 |
| POU3F2 | POU class 3 homeobox 2 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRDM10 | PR domain containing 10 |
| PRF1 | perforin 1 (pore forming protein) |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RRBP1 | ribosome binding protein 1 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SLC39A9 | solute carrier family 39, member 9 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SRRM2 | serine/arginine repetitive matrix 2 |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| TAPBP | TAP binding protein (tapasin) |
| TBX2 | T-box 2 |
| THBS1 | thrombospondin 1 |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| TNN | tenascin N |
| TRAF1 | TNF receptor-associated factor 1 |
| TSPAN9 | tetraspanin 9 |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| ULK4 | unc-51 like kinase 4 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) |
| ZNF132 | zinc finger protein 132 |
| ZNF549 | zinc finger protein 549 |
| ZNF778 | zinc finger protein 778 |
| Symbol | Name |
|---|---|
| ACBD4 | acyl-CoA binding domain containing 4 |
| ACOX2 | acyl-CoA oxidase 2, branched chain |
| ADAP2 | ArfGAP with dual PH domains 2 |
| AKTIP | AKT interacting protein |
| ALPK1 | alpha-kinase 1 |
| AMDHD2 | amidohydrolase domain containing 2 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| AQP9 | aquaporin 9 |
| ART1 | ADP-ribosyltransferase 1 |
| BCORL1 | BCL6 corepressor-like 1 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C9ORF3 | chromosome 9 open reading frame 3 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CBR3 | carbonyl reductase 3 |
| CCDC85C | coiled-coil domain containing 85C |
| CD101 | CD101 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CLIP2 | CAP-GLY domain containing linker protein 2 |
| CNTLN | centlein, centrosomal protein |
| CTC1 | CTS telomere maintenance complex component 1 |
| DDX43 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DNMBP | dynamin binding protein |
| DUSP8 | dual specificity phosphatase 8 |
| DVL1 | dishevelled segment polarity protein 1 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| FKBP5 | FK506 binding protein 5 |
| FLT4 | fms-related tyrosine kinase 4 |
| FOXN2 | forkhead box N2 |
| FOXO4 | forkhead box O4 |
| GPR1 | G protein-coupled receptor 1 |
| GPR132 | G protein-coupled receptor 132 |
| GPR19 | G protein-coupled receptor 19 |
| GRPR | gastrin-releasing peptide receptor |
| GSDMD | gasdermin D |
| HIST1H2BI | histone cluster 1, H2bi |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HRH2 | histamine receptor H2 |
| HSD17B7 | hydroxysteroid (17-beta) dehydrogenase 7 |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IQCC | IQ motif containing C |
| LATS1 | large tumor suppressor kinase 1 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MCPH1 | microcephalin 1 |
| MEFV | Mediterranean fever |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MSMO1 | methylsterol monooxygenase 1 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| NXN | nucleoredoxin |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| P2RY1 | purinergic receptor P2Y, G-protein coupled, 1 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PQLC2 | PQ loop repeat containing 2 |
| PROCR | protein C receptor, endothelial |
| PYGB | phosphorylase, glycogen; brain |
| RBM47 | RNA binding motif protein 47 |
| RND1 | Rho family GTPase 1 |
| RNF167 | ring finger protein 167 |
| RPL10L | ribosomal protein L10-like |
| SCG5 | secretogranin V |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SNAI1 | snail family zinc finger 1 |
| SQLE | squalene epoxidase |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| TCTN2 | tectonic family member 2 |
| TFEC | transcription factor EC |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TMEM140 | transmembrane protein 140 |
| TMEM209 | transmembrane protein 209 |
| TMEM53 | transmembrane protein 53 |
| TSPYL2 | TSPY-like 2 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UNC13B | unc-13 homolog B (C. elegans) |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR62 | WD repeat domain 62 |
| ZBTB16 | zinc finger and BTB domain containing 16 |
| ZFHX4 | zinc finger homeobox 4 |
| ZNF250 | zinc finger protein 250 |
| ZNF276 | zinc finger protein 276 |
| ZNF442 | zinc finger protein 442 |
| ZNF747 | zinc finger protein 747 |
