| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the pregnenolone-2856 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| AGFG1 | ArfGAP with FG repeats 1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ATM | ATM serine/threonine kinase |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 |
| BCL6 | B-cell CLL/lymphoma 6 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CDK12 | cyclin-dependent kinase 12 |
| CERS4 | ceramide synthase 4 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CGA | glycoprotein hormones, alpha polypeptide |
| CLEC11A | C-type lectin domain family 11, member A |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DMXL2 | Dmx-like 2 |
| DOK4 | docking protein 4 |
| DST | dystonin |
| E2F5 | E2F transcription factor 5, p130-binding |
| EGR3 | early growth response 3 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EMID1 | EMI domain containing 1 |
| FCMR | Fc fragment of IgM receptor |
| FFAR2 | free fatty acid receptor 2 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| HFE | hemochromatosis |
| HOXA6 | homeobox A6 |
| IDS | iduronate 2-sulfatase |
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma |
| INHBE | inhibin, beta E |
| INPP1 | inositol polyphosphate-1-phosphatase |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| JUND | jun D proto-oncogene |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KLF9 | Kruppel-like factor 9 |
| KLHL22 | kelch-like family member 22 |
| KRT17 | keratin 17, type I |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LOC157562 | uncharacterized LOC157562 |
| LOXL2 | lysyl oxidase-like 2 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MCM3AP | minichromosome maintenance complex component 3 associated protein |
| MID1 | midline 1 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 |
| MTCP1 | mature T-cell proliferation 1 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| MYO9B | myosin IXB |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NF1 | neurofibromin 1 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLAGL1 | pleiomorphic adenoma gene-like 1 |
| PLXNB3 | plexin B3 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PTGES | prostaglandin E synthase |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RBM19 | RNA binding motif protein 19 |
| RNFT1 | ring finger protein, transmembrane 1 |
| RQCD1 | RCD1 required for cell differentiation1 homolog (S. pombe) |
| S100A2 | S100 calcium binding protein A2 |
| SCAI | suppressor of cancer cell invasion |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC29A1 | solute carrier family 29 (equilibrative nucleoside transporter), member 1 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLN | sarcolipin |
| SMAD3 | SMAD family member 3 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| SYBU | syntabulin (syntaxin-interacting) |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TCP10 | t-complex 10 |
| TEX14 | testis expressed 14 |
| TLR2 | toll-like receptor 2 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TMPRSS6 | transmembrane protease, serine 6 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TUBA3C | tubulin, alpha 3c |
| VASH1 | vasohibin 1 |
| VEGFA | vascular endothelial growth factor A |
| WDR55 | WD repeat domain 55 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZKSCAN5 | zinc finger with KRAB and SCAN domains 5 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF419 | zinc finger protein 419 |
| ZNF652 | zinc finger protein 652 |
| ZNF695 | zinc finger protein 695 |
| Symbol | Name |
|---|---|
| ANKRD28 | ankyrin repeat domain 28 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CAPN15 | calpain 15 |
| CCDC186 | coiled-coil domain containing 186 |
| CCDC25 | coiled-coil domain containing 25 |
| CDK20 | cyclin-dependent kinase 20 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
| CLGN | calmegin |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CORO2A | coronin, actin binding protein, 2A |
| CORT | cortistatin |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CRY2 | cryptochrome circadian clock 2 |
| DMTN | dematin actin binding protein |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DNAL4 | dynein, axonemal, light chain 4 |
| EFHD2 | EF-hand domain family, member D2 |
| EFNA1 | ephrin-A1 |
| EFNA3 | ephrin-A3 |
| ERCC6 | excision repair cross-complementation group 6 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GPATCH2L | G patch domain containing 2-like |
| HIST1H3B | histone cluster 1, H3b |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| IFT140 | intraflagellar transport 140 |
| INSIG2 | insulin induced gene 2 |
| IPO8 | importin 8 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KIAA0319L | KIAA0319-like |
| KIAA0513 | KIAA0513 |
| KLHL21 | kelch-like family member 21 |
| KLK5 | kallikrein-related peptidase 5 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LIN7B | lin-7 homolog B (C. elegans) |
| LPXN | leupaxin |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LZTFL1 | leucine zipper transcription factor-like 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MANBA | mannosidase, beta A, lysosomal |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MB | myoglobin |
| MXD3 | MAX dimerization protein 3 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| P3H1 | prolyl 3-hydroxylase 1 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PODXL2 | podocalyxin-like 2 |
| POLL | polymerase (DNA directed), lambda |
| RAB3D | RAB3D, member RAS oncogene family |
| RIN2 | Ras and Rab interactor 2 |
| RNF170 | ring finger protein 170 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| RRAGB | Ras-related GTP binding B |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SYNC | syncoilin, intermediate filament protein |
| TBC1D19 | TBC1 domain family, member 19 |
| TESK2 | testis-specific kinase 2 |
| TGFB3 | transforming growth factor, beta 3 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TMEM183A | transmembrane protein 183A |
| TMEM242 | transmembrane protein 242 |
| TMEM39B | transmembrane protein 39B |
| TRAIP | TRAF interacting protein |
| USB1 | U6 snRNA biogenesis 1 |
| VEGFC | vascular endothelial growth factor C |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WDR33 | WD repeat domain 33 |
| YY2 | YY2 transcription factor |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZNF227 | zinc finger protein 227 |
| ZNF248 | zinc finger protein 248 |
| ZNF350 | zinc finger protein 350 |
| ZNF768 | zinc finger protein 768 |
| ZNF816 | zinc finger protein 816 |
