| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the pregnenolone-4218 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ADAM3A | ADAM metallopeptidase domain 3A (pseudogene) |
| ADRA1A | adrenoceptor alpha 1A |
| AGXT | alanine-glyoxylate aminotransferase |
| AIM2 | absent in melanoma 2 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ANGPT4 | angiopoietin 4 |
| ATF7IP | activating transcription factor 7 interacting protein |
| BCAM | basal cell adhesion molecule (Lutheran blood group) |
| BLK | BLK proto-oncogene, Src family tyrosine kinase |
| BMPR1B | bone morphogenetic protein receptor, type IB |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| BST1 | bone marrow stromal cell antigen 1 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CA4 | carbonic anhydrase IV |
| CD52 | CD52 molecule |
| CD6 | CD6 molecule |
| CD72 | CD72 molecule |
| CDHR5 | cadherin-related family member 5 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CFAP43 | cilia and flagella associated protein 43 |
| CHIT1 | chitinase 1 (chitotriosidase) |
| COL19A1 | collagen, type XIX, alpha 1 |
| COL2A1 | collagen, type II, alpha 1 |
| CRH | corticotropin releasing hormone |
| CRYBB1 | crystallin, beta B1 |
| CSTA | cystatin A (stefin A) |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 |
| DOPEY1 | dopey family member 1 |
| F7 | coagulation factor VII (serum prothrombin conversion accelerator) |
| FAM163A | family with sequence similarity 163, member A |
| FAM212B | family with sequence similarity 212, member B |
| FGFR2 | fibroblast growth factor receptor 2 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FN1 | fibronectin 1 |
| FRMD8 | FERM domain containing 8 |
| GAL3ST1 | galactose-3-O-sulfotransferase 1 |
| GPR37L1 | G protein-coupled receptor 37 like 1 |
| HESX1 | HESX homeobox 1 |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HTR5A | 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled |
| ICAM4 | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
| IGSF1 | immunoglobulin superfamily, member 1 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KCNMB1 | potassium channel subfamily M regulatory beta subunit 1 |
| KLK3 | kallikrein-related peptidase 3 |
| KSR1 | kinase suppressor of ras 1 |
| LARGE | like-glycosyltransferase |
| LDLR | low density lipoprotein receptor |
| MAGIX | MAGI family member, X-linked |
| MNMIP1 | manchette microtubule inner protein 1 |
| MTMR1 | myotubularin related protein 1 |
| MTNR1A | melatonin receptor 1A |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NPC1L1 | NPC1-like 1 |
| NRXN3 | neurexin 3 |
| NUP88 | nucleoporin 88kDa |
| OR7C1 | olfactory receptor, family 7, subfamily C, member 1 |
| PAX4 | paired box 4 |
| PDPN | podoplanin |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PRB4 | proline-rich protein BstNI subfamily 4 |
| PRTN3 | proteinase 3 |
| PTPRG | protein tyrosine phosphatase, receptor type, G |
| RARA | retinoic acid receptor, alpha |
| RASA3 | RAS p21 protein activator 3 |
| RBM12B | RNA binding motif protein 12B |
| RCE1 | Ras converting CAAX endopeptidase 1 |
| RGS11 | regulator of G-protein signaling 11 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RIN3 | Ras and Rab interactor 3 |
| RUNDC3A | RUN domain containing 3A |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SEZ6L | seizure related 6 homolog (mouse)-like |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC1A6 | solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SOHLH2 | spermatogenesis and oogenesis specific basic helix-loop-helix 2 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) |
| ST8SIA4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| SUPT20H | suppressor of Ty 20 homolog (S. cerevisiae) |
| TAAR5 | trace amine associated receptor 5 |
| TACR1 | tachykinin receptor 1 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TCF3 | transcription factor 3 |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TLL2 | tolloid-like 2 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TRPC2 | transient receptor potential cation channel, subfamily C, member 2, pseudogene |
| USP2 | ubiquitin specific peptidase 2 |
| ZNF280A | zinc finger protein 280A |
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| APTX | aprataxin |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARRB2 | arrestin, beta 2 |
| BAG4 | BCL2-associated athanogene 4 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BTD | biotinidase |
| C1RL | complement component 1, r subcomponent-like |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CDK3 | cyclin-dependent kinase 3 |
| CDK6 | cyclin-dependent kinase 6 |
| CEP112 | centrosomal protein 112kDa |
| CEP131 | centrosomal protein 131kDa |
| CHRDL1 | chordin-like 1 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
| EFNA3 | ephrin-A3 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| EXOC6B | exocyst complex component 6B |
| FAM69A | family with sequence similarity 69, member A |
| FANCC | Fanconi anemia, complementation group C |
| FOXC1 | forkhead box C1 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GID4 | GID complex subunit 4 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPR3 | G protein-coupled receptor 3 |
| HOXA1 | homeobox A1 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IGSF3 | immunoglobulin superfamily, member 3 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL15RA | interleukin 15 receptor, alpha |
| IL7R | interleukin 7 receptor |
| INCENP | inner centromere protein antigens 135/155kDa |
| INF2 | inverted formin, FH2 and WH2 domain containing |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LOC730101 | uncharacterized LOC730101 |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MTA2 | metastasis associated 1 family, member 2 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase |
| NDP | Norrie disease (pseudoglioma) |
| NMB | neuromedin B |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| OSMR | oncostatin M receptor |
| PAX9 | paired box 9 |
| PDE12 | phosphodiesterase 12 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PLD3 | phospholipase D family, member 3 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PROX1 | prospero homeobox 1 |
| PRR15L | proline rich 15-like |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RARS | arginyl-tRNA synthetase |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SCG5 | secretogranin V |
| SIX1 | SIX homeobox 1 |
| SLC35F6 | solute carrier family 35, member F6 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STEAP4 | STEAP family member 4 |
| TESK1 | testis-specific kinase 1 |
| TEX40 | testis expressed 40 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) |
| TMEM120B | transmembrane protein 120B |
| TMEM242 | transmembrane protein 242 |
| TMSB15A | thymosin beta 15a |
| TWISTNB | TWIST neighbor |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| VGF | VGF nerve growth factor inducible |
| VGLL3 | vestigial-like family member 3 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF141 | zinc finger protein 141 |
| ZNF177 | zinc finger protein 177 |
| ZNF254 | zinc finger protein 254 |
| ZNF34 | zinc finger protein 34 |
| ZNF391 | zinc finger protein 391 |
| ZNF770 | zinc finger protein 770 |
