| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the pregnenolone-4802 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ADH7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| ALB | albumin |
| ANAPC5 | anaphase promoting complex subunit 5 |
| APC | adenomatous polyposis coli |
| ATM | ATM serine/threonine kinase |
| BTN2A2 | butyrophilin, subfamily 2, member A2 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CA9 | carbonic anhydrase IX |
| CDC14A | cell division cycle 14A |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CLDND1 | claudin domain containing 1 |
| CTSF | cathepsin F |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| EFNA3 | ephrin-A3 |
| EGR3 | early growth response 3 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ELN | elastin |
| EPHA1 | EPH receptor A1 |
| EPN1 | epsin 1 |
| EXOC5 | exocyst complex component 5 |
| EXOC7 | exocyst complex component 7 |
| FDX1 | ferredoxin 1 |
| FNTB | farnesyltransferase, CAAX box, beta |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GLIPR1 | GLI pathogenesis-related 1 |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HEXA-AS1 | HEXA antisense RNA 1 |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IFT27 | intraflagellar transport 27 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| INA | internexin neuronal intermediate filament protein, alpha |
| ITGA6 | integrin, alpha 6 |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KLHL24 | kelch-like family member 24 |
| KRT32 | keratin 32, type I |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MAOB | monoamine oxidase B |
| MCF2L | MCF.2 cell line derived transforming sequence-like |
| MERTK | MER proto-oncogene, tyrosine kinase |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MRC2 | mannose receptor, C type 2 |
| MTA2 | metastasis associated 1 family, member 2 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| MZF1 | myeloid zinc finger 1 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NF1 | neurofibromin 1 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OSGIN2 | oxidative stress induced growth inhibitor family member 2 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PARD6B | par-6 family cell polarity regulator beta |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| POLL | polymerase (DNA directed), lambda |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| RBBP9 | retinoblastoma binding protein 9 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNFT1 | ring finger protein, transmembrane 1 |
| RPS14 | ribosomal protein S14 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| RUNX3 | runt-related transcription factor 3 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SFTPB | surfactant protein B |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SQLE | squalene epoxidase |
| STK3 | serine/threonine kinase 3 |
| STRA6 | stimulated by retinoic acid 6 |
| SYBU | syntabulin (syntaxin-interacting) |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TMEM212 | transmembrane protein 212 |
| TMPRSS15 | transmembrane protease, serine 15 |
| TMPRSS2 | transmembrane protease, serine 2 |
| TPMT | thiopurine S-methyltransferase |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| VARS | valyl-tRNA synthetase |
| WSCD1 | WSC domain containing 1 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| ZNF473 | zinc finger protein 473 |
| ZNF639 | zinc finger protein 639 |
| ZNF652 | zinc finger protein 652 |
| ZNF695 | zinc finger protein 695 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BLNK | B-cell linker |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CCDC132 | coiled-coil domain containing 132 |
| CCDC186 | coiled-coil domain containing 186 |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CD82 | CD82 molecule |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase |
| CDK3 | cyclin-dependent kinase 3 |
| CFAP44 | cilia and flagella associated protein 44 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CST6 | cystatin E/M |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| EPHA4 | EPH receptor A4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM110B | family with sequence similarity 110, member B |
| FAM120C | family with sequence similarity 120C |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXO2 | F-box protein 2 |
| FLT4 | fms-related tyrosine kinase 4 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| HIST1H4D | histone cluster 1, H4d |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFT54 | intraflagellar transport 54 |
| JMJD4 | jumonji domain containing 4 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLHL28 | kelch-like family member 28 |
| KRT31 | keratin 31, type I |
| LIF | leukemia inhibitory factor |
| LYRM9 | LYR motif containing 9 |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MUC3B | mucin 3B, cell surface associated |
| NRTN | neurturin |
| ONECUT2 | one cut homeobox 2 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCDHB3 | protocadherin beta 3 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PLA2G3 | phospholipase A2, group III |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
| SECTM1 | secreted and transmembrane 1 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SETD1A | SET domain containing 1A |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STK16 | serine/threonine kinase 16 |
| STON1 | stonin 1 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| SYNC | syncoilin, intermediate filament protein |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TMEM121 | transmembrane protein 121 |
| TMEM53 | transmembrane protein 53 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TPK1 | thiamin pyrophosphokinase 1 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TSGA10 | testis specific, 10 |
| UNC119 | unc-119 homolog (C. elegans) |
| XAB2 | XPA binding protein 2 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| XYLT2 | xylosyltransferase II |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF324 | zinc finger protein 324 |
| ZNF580 | zinc finger protein 580 |
| ZNF586 | zinc finger protein 586 |
| ZNF606 | zinc finger protein 606 |
| ZNF747 | zinc finger protein 747 |
| ZNF750 | zinc finger protein 750 |
