premalignant Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

108 genes co-occuring with the biological term premalignant in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AGTR1 angiotensin II receptor, type 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALOX5 arachidonate 5-lipoxygenase
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ATM ATM serine/threonine kinase
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BCL2 B-cell CLL/lymphoma 2
BIN1 bridging integrator 1
BPTF bromodomain PHD finger transcription factor
BRCA1 breast cancer 1, early onset
CAPG capping protein (actin filament), gelsolin-like
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCND1 cyclin D1
CD226 CD226 molecule
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD44 CD44 molecule (Indian blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CLDN4 claudin 4
COL11A1 collagen, type XI, alpha 1
COL1A1 collagen, type I, alpha 1
CTSB cathepsin B
CTTN cortactin
CXCL8 chemokine (C-X-C motif) ligand 8
DLG1 discs, large homolog 1 (Drosophila)
EDNRB endothelin receptor type B
EGFR epidermal growth factor receptor
ENG endoglin
EPOR erythropoietin receptor
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ETV6 ets variant 6
EYA4 EYA transcriptional coactivator and phosphatase 4
FADD Fas (TNFRSF6)-associated via death domain
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
FLT1 fms-related tyrosine kinase 1
GATA4 GATA binding protein 4
GATA6 GATA binding protein 6
GPC3 glypican 3
GREM1 gremlin 1, DAN family BMP antagonist
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
HAND2 heart and neural crest derivatives expressed 2
HDAC1 histone deacetylase 1
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-G major histocompatibility complex, class I, G
HNRNPF heterogeneous nuclear ribonucleoprotein F
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA1B heat shock 70kDa protein 1B
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGF1 insulin-like growth factor 1 (somatomedin C)
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL6 interleukin 6
KRT15 keratin 15, type I
KRT17 keratin 17, type I
KRT5 keratin 5, type II
LCN2 lipocalin 2
LEF1 lymphoid enhancer-binding factor 1
MAPK3 mitogen-activated protein kinase 3
MCM2 minichromosome maintenance complex component 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MGMT O-6-methylguanine-DNA methyltransferase
MIR31 microRNA 31
MKI67 marker of proliferation Ki-67
MLH1 mutL homolog 1
MSH2 mutS homolog 2
MSI1 musashi RNA-binding protein 1
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
NET1 neuroepithelial cell transforming 1
NFE2L2 nuclear factor, erythroid 2-like 2
PAX2 paired box 2
PKM pyruvate kinase, muscle
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PROM1 prominin 1
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RB1 retinoblastoma 1
RBMX RNA binding motif protein, X-linked
RREB1 ras responsive element binding protein 1
RUNX1 runt-related transcription factor 1
SDC1 syndecan 1
SEPT1 septin 1
SFRP1 secreted frizzled-related protein 1
SLC39A3 solute carrier family 39 (zinc transporter), member 3
SSTR3 somatostatin receptor 3
SSTR4 somatostatin receptor 4
SSTR5 somatostatin receptor 5
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STK11 serine/threonine kinase 11
TERT telomerase reverse transcriptase
TGFB1 transforming growth factor, beta 1
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNF tumor necrosis factor
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
TRPV4 transient receptor potential cation channel, subfamily V, member 4
VEGFA vascular endothelial growth factor A
XBP1 X-box binding protein 1