premature aging Gene Set
Genes
35 gene mutations causing the premature aging phenotype in transgenic mice from the MGI Mouse Phenotype Associations 2023 dataset.
| Symbol |
Name |
|
ANP32B
|
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
|
|
ARHGAP1
|
Rho GTPase activating protein 1
|
|
ARNTL
|
aryl hydrocarbon receptor nuclear translocator-like
|
|
ATR
|
ATR serine/threonine kinase
|
|
BUB1B
|
BUB1 mitotic checkpoint serine/threonine kinase B
|
|
CDC14C
|
cell division cycle 14C
|
|
CISD2
|
CDGSH iron sulfur domain 2
|
|
EFEMP1
|
EGF containing fibulin-like extracellular matrix protein 1
|
|
ERCC1
|
excision repair cross-complementation group 1
|
|
ERCC2
|
excision repair cross-complementation group 2
|
|
FSHR
|
follicle stimulating hormone receptor
|
|
HAT1
|
histone acetyltransferase 1
|
|
HELLS
|
helicase, lymphoid-specific
|
|
KL
|
klotho
|
|
LINC-PINT
|
long intergenic non-protein coding RNA, p53 induced transcript
|
|
LINC00657
|
long intergenic non-protein coding RNA 657
|
|
LMNA
|
lamin A/C
|
|
NTMT1
|
N-terminal Xaa-Pro-Lys N-methyltransferase 1
|
|
POLG
|
polymerase (DNA directed), gamma
|
|
PTHLH
|
parathyroid hormone-like hormone
|
|
RASSF9
|
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
|
|
RBM38
|
RNA binding motif protein 38
|
|
RPS9
|
ribosomal protein S9
|
|
SIRT6
|
sirtuin 6
|
|
SIRT7
|
sirtuin 7
|
|
SPRTN
|
SprT-like N-terminal domain
|
|
SQSTM1
|
sequestosome 1
|
|
STAG1
|
stromal antigen 1
|
|
TACO1
|
translational activator of mitochondrially encoded cytochrome c oxidase I
|
|
TIMM23B
|
translocase of inner mitochondrial membrane 23 homolog B (yeast)
|
|
TP53
|
tumor protein p53
|
|
TP63
|
tumor protein p63
|
|
TPP2
|
tripeptidyl peptidase II
|
|
TUSC2
|
tumor suppressor candidate 2
|
|
ZMPSTE24
|
zinc metallopeptidase STE24
|
