premature aging Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
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47 gene mutations causing the premature aging phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AMHR2 anti-Mullerian hormone receptor, type II
ANP32B acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
ARHGAP1 Rho GTPase activating protein 1
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ATR ATR serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CD59 CD59 molecule, complement regulatory protein
CDC14B cell division cycle 14B
CISD2 CDGSH iron sulfur domain 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
FANCA Fanconi anemia, complementation group A
FOXO3 forkhead box O3
FSHR follicle stimulating hormone receptor
FST follistatin
HELLS helicase, lymphoid-specific
JMJD1C jumonji domain containing 1C
KITLG KIT ligand
KL klotho
LMNA lamin A/C
MAGEL2 melanoma antigen family L2
NHLH2 nescient helix loop helix 2
NXF2 nuclear RNA export factor 2
PCSK6 proprotein convertase subtilisin/kexin type 6
PER1 period circadian clock 1
PER2 period circadian clock 2
PFDN5 prefoldin subunit 5
POLG polymerase (DNA directed), gamma
PTHLH parathyroid hormone-like hormone
RASSF9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
SFTPC surfactant protein C
SIRT6 sirtuin 6
SIRT7 sirtuin 7
SPO11 SPO11 meiotic protein covalently bound to DSB
SQSTM1 sequestosome 1
STAG1 stromal antigen 1
T T, brachyury homolog (mouse)
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TERC telomerase RNA component
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast)
TOP3B topoisomerase (DNA) III beta
TP53 tumor protein p53
TP63 tumor protein p63
TPP2 tripeptidyl peptidase II
ZMPSTE24 zinc metallopeptidase STE24