prenylamine-1737 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the prenylamine-1737 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCF2 ATP-binding cassette, sub-family F (GCN20), member 2
AGXT alanine-glyoxylate aminotransferase
AIF1 allograft inflammatory factor 1
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASCC2 activating signal cointegrator 1 complex subunit 2
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CBX6 chromobox homolog 6
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1)
CD8A CD8a molecule
CIZ1 CDKN1A interacting zinc finger protein 1
COQ4 coenzyme Q4
CREB3 cAMP responsive element binding protein 3
CSNK1D casein kinase 1, delta
CXCL10 chemokine (C-X-C motif) ligand 10
CYLD cylindromatosis (turban tumor syndrome)
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DOCK4 dedicator of cytokinesis 4
DPH2 DPH2 homolog (S. cerevisiae)
ECE1 endothelin converting enzyme 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
ETV7 ets variant 7
FANCF Fanconi anemia, complementation group F
FASTK Fas-activated serine/threonine kinase
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GON4L gon-4-like (C. elegans)
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HP1BP3 heterochromatin protein 1, binding protein 3
IFI16 interferon, gamma-inducible protein 16
IFI35 interferon-induced protein 35
IFI44 interferon-induced protein 44
IFI6 interferon, alpha-inducible protein 6
IFIH1 interferon induced with helicase C domain 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IFITM1 interferon induced transmembrane protein 1
INPP5K inositol polyphosphate-5-phosphatase K
IRF7 interferon regulatory factor 7
IRF9 interferon regulatory factor 9
ISG15 ISG15 ubiquitin-like modifier
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGA7 integrin, alpha 7
KDM4B lysine (K)-specific demethylase 4B
KLHL3 kelch-like family member 3
KYNU kynureninase
LAP3 leucine aminopeptidase 3
METTL13 methyltransferase like 13
MFN1 mitofusin 1
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
MT1X metallothionein 1X
MT2A metallothionein 2A
MX1 MX dynamin-like GTPase 1
MX2 MX dynamin-like GTPase 2
NCAPH non-SMC condensin I complex, subunit H
NDRG2 NDRG family member 2
NOL12 nucleolar protein 12
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRIP1 nuclear receptor interacting protein 1
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
NXT2 nuclear transport factor 2-like export factor 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OASL 2'-5'-oligoadenylate synthetase-like
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PARD3 par-3 family cell polarity regulator
PCIF1 PDX1 C-terminal inhibiting factor 1
PDLIM1 PDZ and LIM domain 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
RAB5C RAB5C, member RAS oncogene family
RPLP2 ribosomal protein, large, P2
SAFB scaffold attachment factor B
SAMD9 sterile alpha motif domain containing 9
SBNO1 strawberry notch homolog 1 (Drosophila)
SGK1 serum/glucocorticoid regulated kinase 1
SIGLEC7 sialic acid binding Ig-like lectin 7
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLCO4A1 solute carrier organic anion transporter family, member 4A1
SMG7 SMG7 nonsense mediated mRNA decay factor
SNX11 sorting nexin 11
SP110 SP110 nuclear body protein
STAT1 signal transducer and activator of transcription 1, 91kDa
TCF3 transcription factor 3
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TRIM21 tripartite motif containing 21
TRIM22 tripartite motif containing 22
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBE4B ubiquitination factor E4B
XAF1 XIAP associated factor 1
ZNF24 zinc finger protein 24
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ADORA3 adenosine A3 receptor
ADTRP androgen-dependent TFPI-regulating protein
AHCTF1 AT hook containing transcription factor 1
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
APH1B APH1B gamma secretase subunit
APOBR apolipoprotein B receptor
ASF1B anti-silencing function 1B histone chaperone
ATAD3A ATPase family, AAA domain containing 3A
BLMH bleomycin hydrolase
C1QTNF1 C1q and tumor necrosis factor related protein 1
CCDC176 coiled-coil domain containing 176
CD82 CD82 molecule
CDC45 cell division cycle 45
CDCA4 cell division cycle associated 4
CFAP74 cilia and flagella associated protein 74
CNTD2 cyclin N-terminal domain containing 2
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CRYL1 crystallin, lambda 1
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DPYD dihydropyrimidine dehydrogenase
DRAM1 DNA-damage regulated autophagy modulator 1
DRD5 dopamine receptor D5
DYSF dysferlin
E2F8 E2F transcription factor 8
FBXO5 F-box protein 5
FCHSD2 FCH and double SH3 domains 2
FGL1 fibrinogen-like 1
FIP1L1 factor interacting with PAPOLA and CPSF1
FKTN fukutin
GBAS glioblastoma amplified sequence
H2BFS H2B histone family, member S (pseudogene)
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HELLS helicase, lymphoid-specific
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HOPX HOP homeobox
KIAA1598
KIFC1 kinesin family member C1
LAS1L LAS1-like (S. cerevisiae)
LINC00339 long intergenic non-protein coding RNA 339
LMNB1 lamin B1
LZTR1 leucine-zipper-like transcription regulator 1
MAGOHB mago-nashi homolog B (Drosophila)
MCM9 minichromosome maintenance complex component 9
MOCS2 molybdenum cofactor synthesis 2
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRPL4 mitochondrial ribosomal protein L4
MTG1 mitochondrial ribosome-associated GTPase 1
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NHLRC2 NHL repeat containing 2
NIP7 NIP7, nucleolar pre-rRNA processing protein
NRGN neurogranin (protein kinase C substrate, RC3)
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PARM1 prostate androgen-regulated mucin-like protein 1
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
PEPD peptidase D
PHKG2 phosphorylase kinase, gamma 2 (testis)
PHLDA2 pleckstrin homology-like domain, family A, member 2
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1
PODNL1 podocan-like 1
POTEKP POTE ankyrin domain family, member K, pseudogene
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PPT1 palmitoyl-protein thioesterase 1
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PTTG3P pituitary tumor-transforming 3, pseudogene
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RINT1 RAD50 interactor 1
RP2 retinitis pigmentosa 2 (X-linked recessive)
RRM2 ribonucleotide reductase M2
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SDF2L1 stromal cell-derived factor 2-like 1
SEC61B Sec61 beta subunit
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SPON2 spondin 2, extracellular matrix protein
STAG3 stromal antigen 3
TEX264 testis expressed 264
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
THOP1 thimet oligopeptidase 1
TMEM106C transmembrane protein 106C
TMEM246 transmembrane protein 246
TNRC6B trinucleotide repeat containing 6B
TOE1 target of EGR1, member 1 (nuclear)
TOM1L1 target of myb1 (chicken)-like 1
TRIM9 tripartite motif containing 9
TSPYL2 TSPY-like 2
UBXN8 UBX domain protein 8
UNG uracil-DNA glycosylase
WFDC2 WAP four-disulfide core domain 2
ZNF250 zinc finger protein 250
ZNF770 zinc finger protein 770