prenylamine-2886 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the prenylamine-2886 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
AKR1C1 aldo-keto reductase family 1, member C1
ANXA1 annexin A1
ARC activity-regulated cytoskeleton-associated protein
ATF3 activating transcription factor 3
BAIAP2 BAI1-associated protein 2
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BHLHE40 basic helix-loop-helix family, member e40
BIRC3 baculoviral IAP repeat containing 3
CCNG2 cyclin G2
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DLX2 distal-less homeobox 2
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP4 dual specificity phosphatase 4
EGR1 early growth response 1
ELL2 elongation factor, RNA polymerase II, 2
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSL2 FOS-like antigen 2
FRMD4B FERM domain containing 4B
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GEM GTP binding protein overexpressed in skeletal muscle
GPR137 G protein-coupled receptor 137
GPR87 G protein-coupled receptor 87
GRB10 growth factor receptor-bound protein 10
HBEGF heparin-binding EGF-like growth factor
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H1D histone cluster 1, H1d
HIST1H2AE histone cluster 1, H2ae
HIST1H2BG histone cluster 1, H2bg
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
HIST1H3E histone cluster 1, H3e
HIST1H4H histone cluster 1, H4h
HIST2H2BE histone cluster 2, H2be
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
ICAM1 intercellular adhesion molecule 1
IER2 immediate early response 2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL21R interleukin 21 receptor
IL23A interleukin 23, alpha subunit p19
INHBE inhibin, beta E
IRF1 interferon regulatory factor 1
IRS2 insulin receptor substrate 2
JUN jun proto-oncogene
KLF10 Kruppel-like factor 10
KLF2 Kruppel-like factor 2
KLF4 Kruppel-like factor 4 (gut)
KLF6 Kruppel-like factor 6
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL24 kelch-like family member 24
LARP6 La ribonucleoprotein domain family, member 6
LPIN1 lipin 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
NFIL3 nuclear factor, interleukin 3 regulated
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NUPR1 nuclear protein, transcriptional regulator, 1
OASL 2'-5'-oligoadenylate synthetase-like
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PER1 period circadian clock 1
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PNRC1 proline-rich nuclear receptor coactivator 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RCAN1 regulator of calcineurin 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS2 regulator of G-protein signaling 2
RND1 Rho family GTPase 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SOX9 SRY (sex determining region Y)-box 9
SRCAP Snf2-related CREBBP activator protein
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRIB1 tribbles pseudokinase 1
TRIB3 tribbles pseudokinase 3
VEGFA vascular endothelial growth factor A
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ASIC3 acid sensing (proton gated) ion channel 3
ATAD5 ATPase family, AAA domain containing 5
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BMP4 bone morphogenetic protein 4
C22ORF29 chromosome 22 open reading frame 29
C2ORF54 chromosome 2 open reading frame 54
C7ORF43 chromosome 7 open reading frame 43
CADPS2 Ca++-dependent secretion activator 2
CCNE1 cyclin E1
CCNE2 cyclin E2
CCNO cyclin O
CD302 CD302 molecule
CDK20 cyclin-dependent kinase 20
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CINP cyclin-dependent kinase 2 interacting protein
CLSPN claspin
CORT cortistatin
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CPTP ceramide-1-phosphate transfer protein
CROT carnitine O-octanoyltransferase
CXORF56 chromosome X open reading frame 56
DCAF4 DDB1 and CUL4 associated factor 4
DEAF1 DEAF1 transcription factor
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
E2F8 E2F transcription factor 8
EGLN3 egl-9 family hypoxia-inducible factor 3
EVPL envoplakin
FA2H fatty acid 2-hydroxylase
FAM184A family with sequence similarity 184, member A
FAM188A family with sequence similarity 188, member A
FCHSD2 FCH and double SH3 domains 2
FURIN furin (paired basic amino acid cleaving enzyme)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GK3P glycerol kinase 3 pseudogene
GSTA4 glutathione S-transferase alpha 4
HIST1H4F histone cluster 1, H4f
HOXC11 homeobox C11
HTRA1 HtrA serine peptidase 1
INPP1 inositol polyphosphate-1-phosphatase
KIAA0232 KIAA0232
LAMB2 laminin, beta 2 (laminin S)
LOC257152 uncharacterized LOC257152
LRRC61 leucine rich repeat containing 61
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LYPD1 LY6/PLAUR domain containing 1
MBNL3 muscleblind-like splicing regulator 3
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MMACHC methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
MSMB microseminoprotein, beta-
MTCL1 microtubule crosslinking factor 1
NCS1 neuronal calcium sensor 1
NOL10 nucleolar protein 10
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
PARD6A par-6 family cell polarity regulator alpha
PCDHB8 protocadherin beta 8
PHEX phosphate regulating endopeptidase homolog, X-linked
PITX2 paired-like homeodomain 2
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD3 phospholipase D family, member 3
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PMP22 peripheral myelin protein 22
PNPLA6 patatin-like phospholipase domain containing 6
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PROS1 protein S (alpha)
PRR15L proline rich 15-like
PTDSS2 phosphatidylserine synthase 2
PYCRL pyrroline-5-carboxylate reductase-like
RAB30 RAB30, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RAD51AP1 RAD51 associated protein 1
RETN resistin
RFXAP regulatory factor X-associated protein
RPGRIP1L RPGRIP1-like
SAYSD1 SAYSVFN motif domain containing 1
SCAMP5 secretory carrier membrane protein 5
SCRN3 secernin 3
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SMCO4 single-pass membrane protein with coiled-coil domains 4
SNORA21 small nucleolar RNA, H/ACA box 21
TH tyrosine hydroxylase
TMEM254 transmembrane protein 254
TPCN1 two pore segment channel 1
TRPV6 transient receptor potential cation channel, subfamily V, member 6
VASH2 vasohibin 2
VAX2 ventral anterior homeobox 2
ZNF219 zinc finger protein 219
ZNF747 zinc finger protein 747