prenylamine-5070 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the prenylamine-5070 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
AFF2 AF4/FMR2 family, member 2
ANG angiogenin, ribonuclease, RNase A family, 5
ARC activity-regulated cytoskeleton-associated protein
ARHGAP35 Rho GTPase activating protein 35
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
BAIAP3 BAI1-associated protein 3
C11ORF16 chromosome 11 open reading frame 16
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLCA2 chloride channel accessory 2
CLTA clathrin, light chain A
COL14A1 collagen, type XIV, alpha 1
CTH cystathionine gamma-lyase
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL8 chemokine (C-X-C motif) ligand 8
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
DUSP1 dual specificity phosphatase 1
EGR1 early growth response 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ERO1LB ERO1-like beta (S. cerevisiae)
FOS FBJ murine osteosarcoma viral oncogene homolog
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GADD45B growth arrest and DNA-damage-inducible, beta
GRM7 glutamate receptor, metabotropic 7
GSTA3 glutathione S-transferase alpha 3
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFNB1 interferon, beta 1, fibroblast
IL33R interleukin 33 receptor
IL6 interleukin 6
JUN jun proto-oncogene
JUNB jun B proto-oncogene
JUND jun D proto-oncogene
KDM4B lysine (K)-specific demethylase 4B
KLF6 Kruppel-like factor 6
KLK10 kallikrein-related peptidase 10
KLK7 kallikrein-related peptidase 7
KRT86 keratin 86, type II
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MCM3AP minichromosome maintenance complex component 3 associated protein
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
MT1X metallothionein 1X
NEFM neurofilament, medium polypeptide
NOP16 NOP16 nucleolar protein
NPIPB15 nuclear pore complex interacting protein family, member B15
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUPR1 nuclear protein, transcriptional regulator, 1
OASL 2'-5'-oligoadenylate synthetase-like
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PDE4D phosphodiesterase 4D, cAMP-specific
PDGFA platelet-derived growth factor alpha polypeptide
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PMFBP1 polyamine modulated factor 1 binding protein 1
PPARD peroxisome proliferator-activated receptor delta
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRR protein tyrosine phosphatase, receptor type, R
PYY peptide YY
RGS4 regulator of G-protein signaling 4
RNF19B ring finger protein 19B
RRAD Ras-related associated with diabetes
SAT1 spermidine/spermine N1-acetyltransferase 1
SDF2L1 stromal cell-derived factor 2-like 1
SEC24D SEC24 family member D
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPTBN5 spectrin, beta, non-erythrocytic 5
STARD5 StAR-related lipid transfer (START) domain containing 5
STOM stomatin
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
SYT1 synaptotagmin I
TFF3 trefoil factor 3 (intestinal)
TMEM50B transmembrane protein 50B
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TRIB3 tribbles pseudokinase 3
WIPI1 WD repeat domain, phosphoinositide interacting 1
WNT1 wingless-type MMTV integration site family, member 1
ZMIZ2 zinc finger, MIZ-type containing 2

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ADCY6 adenylate cyclase 6
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALPK1 alpha-kinase 1
ANXA2P1 annexin A2 pseudogene 1
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP4M1 adaptor-related protein complex 4, mu 1 subunit
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2
ATAD2B ATPase family, AAA domain containing 2B
ATP7B ATPase, Cu++ transporting, beta polypeptide
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C4ORF19 chromosome 4 open reading frame 19
CARD8 caspase recruitment domain family, member 8
CBX7 chromobox homolog 7
CCNE2 cyclin E2
CENPT centromere protein T
CEP131 centrosomal protein 131kDa
CFAP44 cilia and flagella associated protein 44
CHMP7 charged multivesicular body protein 7
CIDEC cell death-inducing DFFA-like effector c
CPED1 cadherin-like and PC-esterase domain containing 1
CRYBA2 crystallin, beta A2
CSRNP3 cysteine-serine-rich nuclear protein 3
DHRS11 dehydrogenase/reductase (SDR family) member 11
DNA2 DNA replication helicase/nuclease 2
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
E2F8 E2F transcription factor 8
EDIL3 EGF-like repeats and discoidin I-like domains 3
FAM111A family with sequence similarity 111, member A
FBXL7 F-box and leucine-rich repeat protein 7
FHOD1 formin homology 2 domain containing 1
FURIN furin (paired basic amino acid cleaving enzyme)
FUZ fuzzy planar cell polarity protein
FZD3 frizzled class receptor 3
GLDC glycine dehydrogenase (decarboxylating)
GLI3 GLI family zinc finger 3
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HMHA1 histocompatibility (minor) HA-1
HOMER2 homer scaffolding protein 2
IL4R interleukin 4 receptor
ITPKB inositol-trisphosphate 3-kinase B
KIAA0513 KIAA0513
KIAA0754 KIAA0754
KIAA1462 KIAA1462
KLHDC4 kelch domain containing 4
KRT4 keratin 4, type II
L2HGDH L-2-hydroxyglutarate dehydrogenase
LMBR1L limb development membrane protein 1-like
LOC730101 uncharacterized LOC730101
LRRK1 leucine-rich repeat kinase 1
MAST3 microtubule associated serine/threonine kinase 3
MCM10 minichromosome maintenance complex component 10
MCM3 minichromosome maintenance complex component 3
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MOB3B MOB kinase activator 3B
MTERF1 mitochondrial transcription termination factor 1
MXD3 MAX dimerization protein 3
NDP Norrie disease (pseudoglioma)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NME5 NME/NM23 family member 5
NPY1R neuropeptide Y receptor Y1
NTSR1 neurotensin receptor 1 (high affinity)
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PALMD palmdelphin
PDZK1 PDZ domain containing 1
PEX26 peroxisomal biogenesis factor 26
PLSCR4 phospholipid scramblase 4
POLH polymerase (DNA directed), eta
PRSS53 protease, serine, 53
PTK7 protein tyrosine kinase 7 (inactive)
RHOBTB2 Rho-related BTB domain containing 2
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RUNX3 runt-related transcription factor 3
SESN1 sestrin 1
SH3GL2 SH3-domain GRB2-like 2
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SNTA1 syntrophin, alpha 1
SOD3 superoxide dismutase 3, extracellular
SPIDR scaffolding protein involved in DNA repair
SRD5A3 steroid 5 alpha-reductase 3
SSBP3 single stranded DNA binding protein 3
TMEM8B transmembrane protein 8B
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TOR4A torsin family 4, member A
TSC22D4 TSC22 domain family, member 4
TUBGCP5 tubulin, gamma complex associated protein 5
XYLT2 xylosyltransferase II
ZBTB44 zinc finger and BTB domain containing 44
ZC4H2 zinc finger, C4H2 domain containing
ZNF253 zinc finger protein 253
ZNF606 zinc finger protein 606