| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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199 genes differentially expressed following the prenylamine-5070 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADM | adrenomedullin |
| AFF2 | AF4/FMR2 family, member 2 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF3 | activating transcription factor 3 |
| ATP8A2 | ATPase, aminophospholipid transporter, class I, type 8A, member 2 |
| BAIAP3 | BAI1-associated protein 3 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCA2 | chloride channel accessory 2 |
| CLTA | clathrin, light chain A |
| COL14A1 | collagen, type XIV, alpha 1 |
| CTH | cystathionine gamma-lyase |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DUSP1 | dual specificity phosphatase 1 |
| EGR1 | early growth response 1 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GRM7 | glutamate receptor, metabotropic 7 |
| GSTA3 | glutathione S-transferase alpha 3 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IFNB1 | interferon, beta 1, fibroblast |
| IL33R | interleukin 33 receptor |
| IL6 | interleukin 6 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| JUND | jun D proto-oncogene |
| KDM4B | lysine (K)-specific demethylase 4B |
| KLF6 | Kruppel-like factor 6 |
| KLK10 | kallikrein-related peptidase 10 |
| KLK7 | kallikrein-related peptidase 7 |
| KRT86 | keratin 86, type II |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MCM3AP | minichromosome maintenance complex component 3 associated protein |
| MT1E | metallothionein 1E |
| MT1F | metallothionein 1F |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1M | metallothionein 1M |
| MT1X | metallothionein 1X |
| NEFM | neurofilament, medium polypeptide |
| NOP16 | NOP16 nucleolar protein |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| PYY | peptide YY |
| RGS4 | regulator of G-protein signaling 4 |
| RNF19B | ring finger protein 19B |
| RRAD | Ras-related associated with diabetes |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SEC24D | SEC24 family member D |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| STOM | stomatin |
| SUPT20H | suppressor of Ty 20 homolog (S. cerevisiae) |
| SYT1 | synaptotagmin I |
| TFF3 | trefoil factor 3 (intestinal) |
| TMEM50B | transmembrane protein 50B |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| TRIB3 | tribbles pseudokinase 3 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| Symbol | Name |
|---|---|
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
| ADCY6 | adenylate cyclase 6 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ALPK1 | alpha-kinase 1 |
| ANXA2P1 | annexin A2 pseudogene 1 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| APEX2 | APEX nuclease (apurinic/apyrimidinic endonuclease) 2 |
| ATAD2B | ATPase family, AAA domain containing 2B |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| CARD8 | caspase recruitment domain family, member 8 |
| CBX7 | chromobox homolog 7 |
| CCNE2 | cyclin E2 |
| CENPT | centromere protein T |
| CEP131 | centrosomal protein 131kDa |
| CFAP44 | cilia and flagella associated protein 44 |
| CHMP7 | charged multivesicular body protein 7 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CRYBA2 | crystallin, beta A2 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DNA2 | DNA replication helicase/nuclease 2 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| E2F8 | E2F transcription factor 8 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| FAM111A | family with sequence similarity 111, member A |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FHOD1 | formin homology 2 domain containing 1 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| FUZ | fuzzy planar cell polarity protein |
| FZD3 | frizzled class receptor 3 |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GLI3 | GLI family zinc finger 3 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOMER2 | homer scaffolding protein 2 |
| IL4R | interleukin 4 receptor |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KIAA0513 | KIAA0513 |
| KIAA0754 | KIAA0754 |
| KIAA1462 | KIAA1462 |
| KLHDC4 | kelch domain containing 4 |
| KRT4 | keratin 4, type II |
| L2HGDH | L-2-hydroxyglutarate dehydrogenase |
| LMBR1L | limb development membrane protein 1-like |
| LOC730101 | uncharacterized LOC730101 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM3 | minichromosome maintenance complex component 3 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MOB3B | MOB kinase activator 3B |
| MTERF1 | mitochondrial transcription termination factor 1 |
| MXD3 | MAX dimerization protein 3 |
| NDP | Norrie disease (pseudoglioma) |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NME5 | NME/NM23 family member 5 |
| NPY1R | neuropeptide Y receptor Y1 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PALMD | palmdelphin |
| PDZK1 | PDZ domain containing 1 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PLSCR4 | phospholipid scramblase 4 |
| POLH | polymerase (DNA directed), eta |
| PRSS53 | protease, serine, 53 |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RUNX3 | runt-related transcription factor 3 |
| SESN1 | sestrin 1 |
| SH3GL2 | SH3-domain GRB2-like 2 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SNTA1 | syntrophin, alpha 1 |
| SOD3 | superoxide dismutase 3, extracellular |
| SPIDR | scaffolding protein involved in DNA repair |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SSBP3 | single stranded DNA binding protein 3 |
| TMEM8B | transmembrane protein 8B |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| TOR4A | torsin family 4, member A |
| TSC22D4 | TSC22 domain family, member 4 |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| XYLT2 | xylosyltransferase II |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZC4H2 | zinc finger, C4H2 domain containing |
| ZNF253 | zinc finger protein 253 |
| ZNF606 | zinc finger protein 606 |