prenylamine-5489 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the prenylamine-5489 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ATF3 activating transcription factor 3
BHLHE40 basic helix-loop-helix family, member e40
BLZF1 basic leucine zipper nuclear factor 1
C8ORF60 chromosome 8 open reading frame 60
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCDC132 coiled-coil domain containing 132
CGA glycoprotein hormones, alpha polypeptide
COBLL1 cordon-bleu WH2 repeat protein-like 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP4 dual specificity phosphatase 4
EGR1 early growth response 1
EGR3 early growth response 3
ELMO2 engulfment and cell motility 2
EMC3 ER membrane protein complex subunit 3
FAM214B family with sequence similarity 214, member B
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GBP1 guanylate binding protein 1, interferon-inducible
GEM GTP binding protein overexpressed in skeletal muscle
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPM6B glycoprotein M6B
GPR87 G protein-coupled receptor 87
HBEGF heparin-binding EGF-like growth factor
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H3B histone cluster 1, H3b
HIST1H4D histone cluster 1, H4d
HIST1H4H histone cluster 1, H4h
HLA-DMA major histocompatibility complex, class II, DM alpha
HMOX1 heme oxygenase 1
HNMT histamine N-methyltransferase
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IER2 immediate early response 2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL23A interleukin 23, alpha subunit p19
INHBE inhibin, beta E
INSIG1 insulin induced gene 1
IRF9 interferon regulatory factor 9
IRS2 insulin receptor substrate 2
JUN jun proto-oncogene
KDM6A lysine (K)-specific demethylase 6A
KLF2 Kruppel-like factor 2
KLF6 Kruppel-like factor 6
KLHL24 kelch-like family member 24
KRT2 keratin 2, type II
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LRP12 low density lipoprotein receptor-related protein 12
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MARS methionyl-tRNA synthetase
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
MZF1 myeloid zinc finger 1
NF1 neurofibromin 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
OASL 2'-5'-oligoadenylate synthetase-like
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PROX1 prospero homeobox 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RCAN1 regulator of calcineurin 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
S100A2 S100 calcium binding protein A2
SAT1 spermidine/spermine N1-acetyltransferase 1
SEC24D SEC24 family member D
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
STS steroid sulfatase (microsomal), isozyme S
TH tyrosine hydroxylase
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TPSG1 tryptase gamma 1
TRIB1 tribbles pseudokinase 1
TSC22D3 TSC22 domain family, member 3
VEGFA vascular endothelial growth factor A
VGLL3 vestigial-like family member 3
VTCN1 V-set domain containing T cell activation inhibitor 1
ZC3H7B zinc finger CCCH-type containing 7B
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZSCAN32 zinc finger and SCAN domain containing 32

decreased expression

Symbol Name
ADORA2B adenosine A2b receptor
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
B3GNT1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BAG4 BCL2-associated athanogene 4
C16ORF59 chromosome 16 open reading frame 59
C17ORF70 chromosome 17 open reading frame 70
CBX7 chromobox homolog 7
CCDC88C coiled-coil domain containing 88C
CCNL2 cyclin L2
CENPJ centromere protein J
CEP97 centrosomal protein 97kDa
CHMP6 charged multivesicular body protein 6
CIDEC cell death-inducing DFFA-like effector c
CISH cytokine inducible SH2-containing protein
CPT2 carnitine palmitoyltransferase 2
CTNNBIP1 catenin, beta interacting protein 1
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DCAF16 DDB1 and CUL4 associated factor 16
DENND4A DENN/MADD domain containing 4A
DESI1 desumoylating isopeptidase 1
DNAL4 dynein, axonemal, light chain 4
DSCAM Down syndrome cell adhesion molecule
FAM110B family with sequence similarity 110, member B
FAM169A family with sequence similarity 169, member A
FAM50B family with sequence similarity 50, member B
FAM86C1 family with sequence similarity 86, member C1
FBXO31 F-box protein 31
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
HPS6 Hermansky-Pudlak syndrome 6
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
ITPKB inositol-trisphosphate 3-kinase B
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LIN7B lin-7 homolog B (C. elegans)
LOC100286895 cell division cycle 27 homolog pseudogene
LOC730101 uncharacterized LOC730101
LRRC20 leucine rich repeat containing 20
LRRC42 leucine rich repeat containing 42
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MCRS1 microspherule protein 1
MECR mitochondrial trans-2-enoyl-CoA reductase
MED9 mediator complex subunit 9
MLYCD malonyl-CoA decarboxylase
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MYL5 myosin, light chain 5, regulatory
MYO1F myosin IF
NPFFR1 neuropeptide FF receptor 1
ONECUT2 one cut homeobox 2
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PLEK2 pleckstrin 2
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRKCD protein kinase C, delta
PRKX protein kinase, X-linked
PYCRL pyrroline-5-carboxylate reductase-like
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RIBC2 RIB43A domain with coiled-coils 2
RIC8B RIC8 guanine nucleotide exchange factor B
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF146 ring finger protein 146
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF31 ring finger protein 31
RNF43 ring finger protein 43
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCPEP1 serine carboxypeptidase 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH2B3 SH2B adaptor protein 3
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SPINK5 serine peptidase inhibitor, Kazal type 5
SREK1IP1 SREK1-interacting protein 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TEFM transcription elongation factor, mitochondrial
TESC tescalcin
TPST2 tyrosylprotein sulfotransferase 2
TRAIP TRAF interacting protein
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TTC33 tetratricopeptide repeat domain 33
TUBA3C tubulin, alpha 3c
TUBA3D tubulin, alpha 3d
TUBG2 tubulin, gamma 2
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZBED1 zinc finger, BED-type containing 1
ZNF365 zinc finger protein 365
ZNF639 zinc finger protein 639
ZNF692 zinc finger protein 692