presynaptic active zone Gene Set

Dataset GO Cellular Component Annotations
Category structural or functional annotations
Type cellular component
Description A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, synaptic vesicles, and a specialized cortical cytoskeletal matrix. (Gene Ontology, GO_0048786)
External Link http://amigo.geneontology.org/amigo/term/GO:0048786
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Genes

22 proteins localized to the presynaptic active zone cellular component from the curated GO Cellular Component Annotations dataset.

Symbol Name
ADORA1 adenosine A1 receptor
BSN bassoon presynaptic cytomatrix protein
ERC2 ELKS/RAB6-interacting/CAST family member 2
FZD3 frizzled class receptor 3
GPER1 G protein-coupled estrogen receptor 1
GRM7 glutamate receptor, metabotropic 7
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
RIMS1 regulating synaptic membrane exocytosis 1
RIMS2 regulating synaptic membrane exocytosis 2
RIMS3 regulating synaptic membrane exocytosis 3
RIMS4 regulating synaptic membrane exocytosis 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SV2A synaptic vesicle glycoprotein 2A
SYP synaptophysin
UNC13A unc-13 homolog A (C. elegans)
UNC13B unc-13 homolog B (C. elegans)
UNC13C unc-13 homolog C (C. elegans)
Funding