previous Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

442 genes co-occuring with the biological term previous in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
ACE angiotensin I converting enzyme
ACTG1 actin gamma 1
ACTN3 actinin, alpha 3 (gene/pseudogene)
ADAM12 ADAM metallopeptidase domain 12
ADCY5 adenylate cyclase 5
ADD1 adducin 1 (alpha)
ADIPOQ adiponectin, C1Q and collagen domain containing
ADK adenosine kinase
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AHR aryl hydrocarbon receptor
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALK anaplastic lymphoma receptor tyrosine kinase
AMH anti-Mullerian hormone
ANGPTL7 angiopoietin-like 7
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANKK1 ankyrin repeat and kinase domain containing 1
AOC3 amine oxidase, copper containing 3
APC adenomatous polyposis coli
APOA1 apolipoprotein A-I
APOA4 apolipoprotein A-IV
APOA5 apolipoprotein A-V
APOB apolipoprotein B
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AQP1 aquaporin 1 (Colton blood group)
AQP4 aquaporin 4
AR androgen receptor
ARMS2 age-related maculopathy susceptibility 2
ASXL1 additional sex combs like transcriptional regulator 1
ATM ATM serine/threonine kinase
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
ATXN3 ataxin 3
AXIN1 axin 1
AXL AXL receptor tyrosine kinase
BCHE butyrylcholinesterase
BDNF brain-derived neurotrophic factor
BGLAP bone gamma-carboxyglutamate (gla) protein
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CA8 carbonic anhydrase VIII
CASP6 caspase 6, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CCL2 chemokine (C-C motif) ligand 2
CCL26 chemokine (C-C motif) ligand 26
CCL3 chemokine (C-C motif) ligand 3
CCL5 chemokine (C-C motif) ligand 5
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD163 CD163 molecule
CD209 CD209 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD44 CD44 molecule (Indian blood group)
CD59 CD59 molecule, complement regulatory protein
CD70 CD70 molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFH complement factor H
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHKB choline kinase beta
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle)
CHST6 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
CIITA class II, major histocompatibility complex, transactivator
CLIC1 chloride intracellular channel 1
CLN3 ceroid-lipofuscinosis, neuronal 3
CLOCK clock circadian regulator
CNA1 cornea plana 1 (autosomal dominant)
CNR1 cannabinoid receptor 1 (brain)
CNTF ciliary neurotrophic factor
COL1A1 collagen, type I, alpha 1
COL3A1 collagen, type III, alpha 1
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
COMT catechol-O-methyltransferase
CPT1B carnitine palmitoyltransferase 1B (muscle)
CR2 complement component (3d/Epstein Barr virus) receptor 2
CREB1 cAMP responsive element binding protein 1
CRP C-reactive protein, pentraxin-related
CRTC1 CREB regulated transcription coactivator 1
CRYGD crystallin, gamma D
CTAG1B cancer/testis antigen 1B
CTGF connective tissue growth factor
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSB cathepsin B
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP46A1 cytochrome P450, family 46, subfamily A, polypeptide 1
DAO D-amino-acid oxidase
DAOA D-amino acid oxidase activator
DCD dermcidin
DEFB1 defensin, beta 1
DMD dystrophin
DRD2 dopamine receptor D2
DRD4 dopamine receptor D4
DTNBP1 dystrobrevin binding protein 1
DVL3 dishevelled segment polarity protein 3
DYSF dysferlin
E2F1 E2F transcription factor 1
ECD ecdysoneless homolog (Drosophila)
EDN1 endothelin 1
EDNRA endothelin receptor type A
EGFR epidermal growth factor receptor
EGR3 early growth response 3
ELN elastin
EPAS1 endothelial PAS domain protein 1
EPHA2 EPH receptor A2
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ESCO2 establishment of sister chromatid cohesion N-acetyltransferase 2
ESR1 estrogen receptor 1
ETV6 ets variant 6
EYS eyes shut homolog (Drosophila)
EZR ezrin
F2 coagulation factor II (thrombin)
F5 coagulation factor V (proaccelerin, labile factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FAF1 Fas (TNFRSF6) associated factor 1
FAS Fas cell surface death receptor
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FCRL3 Fc receptor-like 3
FFAR2 free fatty acid receptor 2
FGFR2 fibroblast growth factor receptor 2
FIP1L1 factor interacting with PAPOLA and CPSF1
FLG filaggrin
FLNC filamin C, gamma
FLT1 fms-related tyrosine kinase 1
FMR1 fragile X mental retardation 1
FOXF1 forkhead box F1
FOXG1 forkhead box G1
FOXL2 forkhead box L2
FOXP2 forkhead box P2
FTL ferritin, light polypeptide
FUS FUS RNA binding protein
FUT2 fucosyltransferase 2 (secretor status included)
FXN frataxin
FYN FYN proto-oncogene, Src family tyrosine kinase
FZD4 frizzled class receptor 4
FZD5 frizzled class receptor 5
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GATA3 GATA binding protein 3
GATA4 GATA binding protein 4
GBA glucosidase, beta, acid
GCH1 GTP cyclohydrolase 1
GDF5 growth differentiation factor 5
GFER growth factor, augmenter of liver regeneration
GHRH growth hormone releasing hormone
GJB2 gap junction protein, beta 2, 26kDa
GNAS GNAS complex locus
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GPR143 G protein-coupled receptor 143
GRIK2 glutamate receptor, ionotropic, kainate 2
GRM3 glutamate receptor, metabotropic 3
GRM7 glutamate receptor, metabotropic 7
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
HAMP hepcidin antimicrobial peptide
HBA2 hemoglobin, alpha 2
HCRT hypocretin (orexin) neuropeptide precursor
HFE hemochromatosis
HFE2 hemochromatosis type 2 (juvenile)
HHEX hematopoietically expressed homeobox
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGA2 high mobility group AT-hook 2
HMOX1 heme oxygenase 1
HNMT histamine N-methyltransferase
HOXA11 homeobox A11
HP haptoglobin
HPSE2 heparanase 2 (inactive)
HSPA4 heat shock 70kDa protein 4
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTRA1 HtrA serine peptidase 1
ICAM1 intercellular adhesion molecule 1
IDE insulin-degrading enzyme
IGF1 insulin-like growth factor 1 (somatomedin C)
IL10 interleukin 10
IL17A interleukin 17A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL23A interleukin 23, alpha subunit p19
IL23R interleukin 23 receptor
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
IL6 interleukin 6
INHA inhibin, alpha
INS insulin
INSL3 insulin-like 3 (Leydig cell)
IRF7 interferon regulatory factor 7
IRS1 insulin receptor substrate 1
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JAK2 Janus kinase 2
JAK3 Janus kinase 3
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KDR kinase insert domain receptor
KIAA0319 KIAA0319
KIF6 kinesin family member 6
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF1 Kruppel-like factor 1 (erythroid)
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRAS Kirsten rat sarcoma viral oncogene homolog
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LIG3 ligase III, DNA, ATP-dependent
LRRK2 leucine-rich repeat kinase 2
LSM1 LSM1, U6 small nuclear RNA associated
LTA lymphotoxin alpha
LTF lactotransferrin
LY86 lymphocyte antigen 86
LYN LYN proto-oncogene, Src family tyrosine kinase
MADD MAP-kinase activating death domain
MAML2 mastermind-like 2 (Drosophila)
MAOA monoamine oxidase A
MAP2 microtubule-associated protein 2
MAPT microtubule-associated protein tau
MATN3 matrilin 3
MBL2 mannose-binding lectin (protein C) 2, soluble
MC4R melanocortin 4 receptor
MECP2 methyl CpG binding protein 2
MEFV Mediterranean fever
MEN1 multiple endocrine neoplasia I
MFN2 mitofusin 2
MFRP membrane frizzled-related protein
MGMT O-6-methylguanine-DNA methyltransferase
MICA MHC class I polypeptide-related sequence A
MICB MHC class I polypeptide-related sequence B
MLH1 mutL homolog 1
MMP1 matrix metallopeptidase 1
MMP10 matrix metallopeptidase 10
MMP12 matrix metallopeptidase 12
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
MPG N-methylpurine-DNA glycosylase
MPO myeloperoxidase
MT-ND4 NADH dehydrogenase, subunit 4 (complex I)
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTNR1B melatonin receptor 1B
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MYB v-myb avian myeloblastosis viral oncogene homolog
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYO9B myosin IXB
NCF1 neutrophil cytosolic factor 1
NCSTN nicastrin
NLRP7 NLR family, pyrin domain containing 7
NOD2 nucleotide-binding oligomerization domain containing 2
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH3 notch 3
NOTCH4 notch 4
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPPB natriuretic peptide B
NQO1 NAD(P)H dehydrogenase, quinone 1
NQO2 NAD(P)H dehydrogenase, quinone 2
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR1I2 nuclear receptor subfamily 1, group I, member 2
NRG1 neuregulin 1
PALB2 partner and localizer of BRCA2
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PARP1 poly (ADP-ribose) polymerase 1
PAX6 paired box 6
PAX7 paired box 7
PCA3 prostate cancer associated 3 (non-protein coding)
PDGFD platelet derived growth factor D
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PER3 period circadian clock 3
PGLYRP3 peptidoglycan recognition protein 3
PGLYRP4 peptidoglycan recognition protein 4
PHEX phosphate regulating endopeptidase homolog, X-linked
PHF3 PHD finger protein 3
PICALM phosphatidylinositol binding clathrin assembly protein
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PITX2 paired-like homeodomain 2
PLAU plasminogen activator, urokinase
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
POMC proopiomelanocortin
PON1 paraoxonase 1
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRNP prion protein
PROX1 prospero homeobox 1
PRPH2 peripherin 2 (retinal degeneration, slow)
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTMA prothymosin, alpha
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
PTX3 pentraxin 3, long
PXN paxillin
RALBP1 ralA binding protein 1
RBP4 retinol binding protein 4, plasma
RCAN1 regulator of calcineurin 1
RELN reelin
REPS2 RALBP1 associated Eps domain containing 2
RGS2 regulator of G-protein signaling 2
RGS4 regulator of G-protein signaling 4
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPGR retinitis pigmentosa GTPase regulator
RRAS related RAS viral (r-ras) oncogene homolog
S100A8 S100 calcium binding protein A8
S100B S100 calcium binding protein B
SAG S-antigen; retina and pineal gland (arrestin)
SAT1 spermidine/spermine N1-acetyltransferase 1
SATB1 SATB homeobox 1
SATB2 SATB homeobox 2
SDC1 syndecan 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SETBP1 SET binding protein 1
SHOX short stature homeobox
SIL1 SIL1 nucleotide exchange factor
SIX6 SIX homeobox 6
SKI SKI proto-oncogene
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1
SLC34A1 solute carrier family 34 (type II sodium/phosphate cotransporter), member 1
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLPI secretory leukocyte peptidase inhibitor
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMAD5 SMAD family member 5
SMAD7 SMAD family member 7
SMAD9 SMAD family member 9
SNAP25 synaptosomal-associated protein, 25kDa
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD1 superoxide dismutase 1, soluble
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX9 SRY (sex determining region Y)-box 9
SPHK1 sphingosine kinase 1
SPP1 secreted phosphoprotein 1
SRSF2 serine/arginine-rich splicing factor 2
SRY sex determining region Y
STAT4 signal transducer and activator of transcription 4
STK11 serine/threonine kinase 11
STXBP1 syntaxin binding protein 1
SUMO4 small ubiquitin-like modifier 4
SYK spleen tyrosine kinase
TAAR1 trace amine associated receptor 1
TAAR2 trace amine associated receptor 2
TAAR3 trace amine associated receptor 3 (gene/pseudogene)
TAAR4P trace amine associated receptor 4, pseudogene
TAAR5 trace amine associated receptor 5
TAAR6 trace amine associated receptor 6
TAAR7P trace amine associated receptor 7, pseudogene
TAAR8 trace amine associated receptor 8
TAAR9 trace amine associated receptor 9 (gene/pseudogene)
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2
TAC3 tachykinin 3
TBX3 T-box 3
TERC telomerase RNA component
TERT telomerase reverse transcriptase
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFR2 transferrin receptor 2
TG thyroglobulin
TGFB1 transforming growth factor, beta 1
TGIF1 TGFB-induced factor homeobox 1
TGM2 transglutaminase 2
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNNC1 troponin C type 1 (slow)
TNNI3 troponin I type 3 (cardiac)
TNNT2 troponin T type 2 (cardiac)
TP53 tumor protein p53
TP53INP1 tumor protein p53 inducible nuclear protein 1
TPMT thiopurine S-methyltransferase
TPO thyroid peroxidase
TRB T cell receptor beta locus
TREX1 three prime repair exonuclease 1
TRIB3 tribbles pseudokinase 3
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TYMP thymidine phosphorylase
UBE3A ubiquitin protein ligase E3A
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UMOD uromodulin
VAX1 ventral anterior homeobox 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VKORC1 vitamin K epoxide reductase complex, subunit 1
VSX1 visual system homeobox 1
VWF von Willebrand factor
WFS1 Wolfram syndrome 1 (wolframin)
WNT4 wingless-type MMTV integration site family, member 4
YEATS4 YEATS domain containing 4
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZEB1 zinc finger E-box binding homeobox 1
ZNF804A zinc finger protein 804A