| Dataset | GeneRIF Biological Term Annotations |
| Category | structural or functional annotations |
| Type | biological term |
| Description | prickle homolog 1 (Drosophila)|This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 144165) |
| Similar Terms | |
| Downloads & Tools |
5 genes co-occuring with the biological term prickle1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
