pridinol-3456 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the pridinol-3456 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADARB1 adenosine deaminase, RNA-specific, B1
AHI1 Abelson helper integration site 1
AK2 adenylate kinase 2
ALMS1 Alstrom syndrome protein 1
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ARC activity-regulated cytoskeleton-associated protein
AREG amphiregulin
ARTN artemin
ATXN7L3B ataxin 7-like 3B
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BHLHE41 basic helix-loop-helix family, member e41
BTBD7 BTB (POZ) domain containing 7
C8ORF44 chromosome 8 open reading frame 44
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD82 CD82 molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CEMIP cell migration inducing protein, hyaluronan binding
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
COL13A1 collagen, type XIII, alpha 1
COL1A1 collagen, type I, alpha 1
CUZD1 CUB and zona pellucida-like domains 1
CXCL12 chemokine (C-X-C motif) ligand 12
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DNAI2 dynein, axonemal, intermediate chain 2
DOK4 docking protein 4
E2F5 E2F transcription factor 5, p130-binding
EGR3 early growth response 3
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ERCC4 excision repair cross-complementation group 4
EXOC7 exocyst complex component 7
F2R coagulation factor II (thrombin) receptor
FKBP8 FK506 binding protein 8, 38kDa
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GAL galanin/GMAP prepropeptide
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLRX3 glutaredoxin 3
GPATCH4 G patch domain containing 4
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HOXC8 homeobox C8
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IGFBP5 insulin-like growth factor binding protein 5
IL1A interleukin 1, alpha
IL6ST interleukin 6 signal transducer
INHBE inhibin, beta E
KAZN kazrin, periplakin interacting protein
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KIAA0100 KIAA0100
KREMEN2 kringle containing transmembrane protein 2
KRT17 keratin 17, type I
LMO4 LIM domain only 4
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LTBP4 latent transforming growth factor beta binding protein 4
LY6D lymphocyte antigen 6 complex, locus D
MED18 mediator complex subunit 18
MSI1 musashi RNA-binding protein 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NGLY1 N-glycanase 1
NUP188 nucleoporin 188kDa
PDZK1 PDZ domain containing 1
PGR progesterone receptor
PHC3 polyhomeotic homolog 3 (Drosophila)
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PPIA peptidylprolyl isomerase A (cyclophilin A)
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKCE protein kinase C, epsilon
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
PVR poliovirus receptor
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RNF6 ring finger protein (C3H2C3 type) 6
RNFT1 ring finger protein, transmembrane 1
SH2D3A SH2 domain containing 3A
SHARPIN SHANK-associated RH domain interactor
SIK3 SIK family kinase 3
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAZ tafazzin
TBL1X transducin (beta)-like 1X-linked
TMEM209 transmembrane protein 209
TMPRSS3 transmembrane protease, serine 3
TREX1 three prime repair exonuclease 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF329 zinc finger protein 329
ZNF428 zinc finger protein 428
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ABHD4 abhydrolase domain containing 4
ACTL8 actin-like 8
AP1B1 adaptor-related protein complex 1, beta 1 subunit
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BGLAP bone gamma-carboxyglutamate (gla) protein
C11ORF80 chromosome 11 open reading frame 80
C1ORF159 chromosome 1 open reading frame 159
C1ORF35 chromosome 1 open reading frame 35
C2ORF54 chromosome 2 open reading frame 54
CAPG capping protein (actin filament), gelsolin-like
CCDC121 coiled-coil domain containing 121
CCDC85C coiled-coil domain containing 85C
CDK3 cyclin-dependent kinase 3
CIR1 corepressor interacting with RBPJ, 1
CLDN15 claudin 15
CLDN9 claudin 9
CTC1 CTS telomere maintenance complex component 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTNNBIP1 catenin, beta interacting protein 1
CTSK cathepsin K
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DOCK1 dedicator of cytokinesis 1
ECHDC2 enoyl CoA hydratase domain containing 2
EFNA1 ephrin-A1
EGLN3 egl-9 family hypoxia-inducible factor 3
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ELMO3 engulfment and cell motility 3
ETAA1 Ewing tumor-associated antigen 1
FAM169A family with sequence similarity 169, member A
FBXL6 F-box and leucine-rich repeat protein 6
FPGS folylpolyglutamate synthase
FSD1 fibronectin type III and SPRY domain containing 1
GALT galactose-1-phosphate uridylyltransferase
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPATCH3 G patch domain containing 3
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2
HLA-J major histocompatibility complex, class I, J (pseudogene)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IL17RA interleukin 17 receptor A
IPO8 importin 8
IRF9 interferon regulatory factor 9
KIAA0430 KIAA0430
KIF13B kinesin family member 13B
LAMB2 laminin, beta 2 (laminin S)
LINS lines homolog (Drosophila)
LOC390998 ribosomal protein L10 pseudogene
LRRC8E leucine rich repeat containing 8 family, member E
LYPD1 LY6/PLAUR domain containing 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAST3 microtubule associated serine/threonine kinase 3
NAT9 N-acetyltransferase 9 (GCN5-related, putative)
NEK11 NIMA-related kinase 11
NPIPB15 nuclear pore complex interacting protein family, member B15
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OXTR oxytocin receptor
PARP16 poly (ADP-ribose) polymerase family, member 16
PHC1 polyhomeotic homolog 1 (Drosophila)
PLA2G3 phospholipase A2, group III
PLD3 phospholipase D family, member 3
PMCH pro-melanin-concentrating hormone
PROS1 protein S (alpha)
RECQL4 RecQ protein-like 4
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPAP1 RNA polymerase II associated protein 1
RPGR retinitis pigmentosa GTPase regulator
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC12A8 solute carrier family 12, member 8
SLC22A14 solute carrier family 22, member 14
SP1 Sp1 transcription factor
STK25 serine/threonine kinase 25
STX5 syntaxin 5
SYNGR3 synaptogyrin 3
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TARP TCR gamma alternate reading frame protein
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCTN1 tectonic family member 1
THBS3 thrombospondin 3
THRAP3 thyroid hormone receptor associated protein 3
TMEM62 transmembrane protein 62
TRIM45 tripartite motif containing 45
TSPYL2 TSPY-like 2
TUBA3C tubulin, alpha 3c
TXNL4B thioredoxin-like 4B
USP27X ubiquitin specific peptidase 27, X-linked
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
WDR33 WD repeat domain 33
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF747 zinc finger protein 747