pridinol-5860 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the pridinol-5860 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACACA acetyl-CoA carboxylase alpha
ACTN2 actinin, alpha 2
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AIM1L absent in melanoma 1-like
ANGPT4 angiopoietin 4
ANGPTL2 angiopoietin-like 2
ARMC9 armadillo repeat containing 9
ARNT aryl hydrocarbon receptor nuclear translocator
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATP10B ATPase, class V, type 10B
C1ORF54 chromosome 1 open reading frame 54
C22ORF46 chromosome 22 open reading frame 46
C8ORF4 chromosome 8 open reading frame 4
CCDC186 coiled-coil domain containing 186
CCDC85B coiled-coil domain containing 85B
CCKAR cholecystokinin A receptor
CD86 CD86 molecule
CDC25A cell division cycle 25A
CDHR2 cadherin-related family member 2
CHAT choline O-acetyltransferase
CLCN4 chloride channel, voltage-sensitive 4
CST4 cystatin S
CTAGE1 cutaneous T-cell lymphoma-associated antigen 1
CTNS cystinosin, lysosomal cystine transporter
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11
DMBT1 deleted in malignant brain tumors 1
DNAAF1 dynein, axonemal, assembly factor 1
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DOK5 docking protein 5
E2F4 E2F transcription factor 4, p107/p130-binding
FAM214B family with sequence similarity 214, member B
FGF18 fibroblast growth factor 18
FN1 fibronectin 1
GEMIN8 gem (nuclear organelle) associated protein 8
GOLGA8A golgin A8 family, member A
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HYAL3 hyaluronoglucosaminidase 3
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IGFBP5 insulin-like growth factor binding protein 5
IGHA1 immunoglobulin heavy constant alpha 1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
ISYNA1 inositol-3-phosphate synthase 1
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
JRK Jrk homolog (mouse)
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KIAA0319L KIAA0319-like
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KPNA5 karyopherin alpha 5 (importin alpha 6)
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MEFV Mediterranean fever
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MPO myeloperoxidase
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MSTN myostatin
MTCP1 mature T-cell proliferation 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTMR1 myotubularin related protein 1
NF1 neurofibromin 1
NFX1 nuclear transcription factor, X-box binding 1
NOVA2 neuro-oncological ventral antigen 2
NOX1 NADPH oxidase 1
ONECUT2 one cut homeobox 2
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PNMAL1 paraneoplastic Ma antigen family-like 1
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RAB31 RAB31, member RAS oncogene family
RAD50 RAD50 homolog (S. cerevisiae)
RANGAP1 Ran GTPase activating protein 1
RBM12B RNA binding motif protein 12B
SC5D sterol-C5-desaturase
SIRT5 sirtuin 5
SIX2 SIX homeobox 2
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SORBS1 sorbin and SH3 domain containing 1
SOSTDC1 sclerostin domain containing 1
SOX2 SRY (sex determining region Y)-box 2
SPATA6 spermatogenesis associated 6
SPTB spectrin, beta, erythrocytic
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAC SH3 and cysteine rich domain
TBL2 transducin (beta)-like 2
TDO2 tryptophan 2,3-dioxygenase
TLE4 transducin-like enhancer of split 4
TP53I11 tumor protein p53 inducible protein 11
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPC3 transient receptor potential cation channel, subfamily C, member 3
UBOX5 U-box domain containing 5
UBXN1 UBX domain protein 1
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
USP5 ubiquitin specific peptidase 5 (isopeptidase T)

decreased expression

Symbol Name
ACAD8 acyl-CoA dehydrogenase family, member 8
ALS2CL ALS2 C-terminal like
ANAPC2 anaphase promoting complex subunit 2
ATP7B ATPase, Cu++ transporting, beta polypeptide
C17ORF70 chromosome 17 open reading frame 70
CAMTA2 calmodulin binding transcription activator 2
CCDC106 coiled-coil domain containing 106
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CENPQ centromere protein Q
CGREF1 cell growth regulator with EF-hand domain 1
CHMP1A charged multivesicular body protein 1A
CNKSR1 connector enhancer of kinase suppressor of Ras 1
DCAF17 DDB1 and CUL4 associated factor 17
DCLRE1A DNA cross-link repair 1A
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNA3 ephrin-A3
EPPK1 epiplakin 1
ERN2 endoplasmic reticulum to nucleus signaling 2
EVPL envoplakin
FADS2 fatty acid desaturase 2
FAF1 Fas (TNFRSF6) associated factor 1
FAM188A family with sequence similarity 188, member A
FAM53B family with sequence similarity 53, member B
GLT8D2 glycosyltransferase 8 domain containing 2
GSTT1 glutathione S-transferase theta 1
HAMP hepcidin antimicrobial peptide
HHLA3 HERV-H LTR-associating 3
HIST1H3G histone cluster 1, H3g
HMHA1 histocompatibility (minor) HA-1
IFT46 intraflagellar transport 46
IMPACT impact RWD domain protein
INCENP inner centromere protein antigens 135/155kDa
INF2 inverted formin, FH2 and WH2 domain containing
IRF9 interferon regulatory factor 9
KCTD7 potassium channel tetramerization domain containing 7
KLHL12 kelch-like family member 12
KLK6 kallikrein-related peptidase 6
KRT15 keratin 15, type I
KRT75 keratin 75, type II
LMBR1L limb development membrane protein 1-like
LYPD3 LY6/PLAUR domain containing 3
MAST3 microtubule associated serine/threonine kinase 3
MCRS1 microspherule protein 1
MOGS mannosyl-oligosaccharide glucosidase
MOXD1 monooxygenase, DBH-like 1
MPP1 membrane protein, palmitoylated 1, 55kDa
MTG1 mitochondrial ribosome-associated GTPase 1
NAG18 NAG18 mRNA
NPM3 nucleophosmin/nucleoplasmin 3
NRSN2 neurensin 2
NUPR1 nuclear protein, transcriptional regulator, 1
PGM3 phosphoglucomutase 3
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
POLM polymerase (DNA directed), mu
PPAN peter pan homolog (Drosophila)
PRR14L proline rich 14-like
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
RGCC regulator of cell cycle
RNF122 ring finger protein 122
RPGR retinitis pigmentosa GTPase regulator
RPH3AL rabphilin 3A-like (without C2 domains)
SCD5 stearoyl-CoA desaturase 5
SCN1B sodium channel, voltage gated, type I beta subunit
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SREBF1 sterol regulatory element binding transcription factor 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STX5 syntaxin 5
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TESK2 testis-specific kinase 2
TGS1 trimethylguanosine synthase 1
TLN1 talin 1
TMEM132A transmembrane protein 132A
TMEM57 transmembrane protein 57
TMEM62 transmembrane protein 62
TMEM8A transmembrane protein 8A
TRAPPC6A trafficking protein particle complex 6A
TRIM21 tripartite motif containing 21
TSKU tsukushi, small leucine rich proteoglycan
TUBA3C tubulin, alpha 3c
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
ZBED1 zinc finger, BED-type containing 1
ZBTB39 zinc finger and BTB domain containing 39
ZBTB48 zinc finger and BTB domain containing 48
ZMYM1 zinc finger, MYM-type 1
ZNF16 zinc finger protein 16
ZNF34 zinc finger protein 34
ZNF552 zinc finger protein 552
ZNF770 zinc finger protein 770
ZNF839 zinc finger protein 839