pridinol-7214 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the pridinol-7214 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACAA2 acetyl-CoA acyltransferase 2
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ATXN3 ataxin 3
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BMP8A bone morphogenetic protein 8a
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BTF3P11 basic transcription factor 3 pseudogene 11
C19ORF57 chromosome 19 open reading frame 57
CA5BP1 carbonic anhydrase VB pseudogene 1
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CD52 CD52 molecule
COL14A1 collagen, type XIV, alpha 1
CTAG2 cancer/testis antigen 2
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2
DAAM2 dishevelled associated activator of morphogenesis 2
DCX doublecortin
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DIAPH2 diaphanous-related formin 2
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DPF1 D4, zinc and double PHD fingers family 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF3F eukaryotic translation initiation factor 3, subunit F
EML1 echinoderm microtubule associated protein like 1
EYA3 EYA transcriptional coactivator and phosphatase 3
FAM214B family with sequence similarity 214, member B
FBLN1 fibulin 1
FCAR Fc fragment of IgA receptor
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAMT guanidinoacetate N-methyltransferase
GRK5 G protein-coupled receptor kinase 5
GRM8 glutamate receptor, metabotropic 8
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
ICOSLG inducible T-cell co-stimulator ligand
IFIH1 interferon induced with helicase C domain 1
IFT122 intraflagellar transport 122
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
ITM2C integral membrane protein 2C
KANSL3 KAT8 regulatory NSL complex subunit 3
KLF9 Kruppel-like factor 9
KSR1 kinase suppressor of ras 1
LEF1 lymphoid enhancer-binding factor 1
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LRRN3 leucine rich repeat neuronal 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAPK8 mitogen-activated protein kinase 8
MEFV Mediterranean fever
METTL7A methyltransferase like 7A
MIIP migration and invasion inhibitory protein
MNDA myeloid cell nuclear differentiation antigen
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MYOZ2 myozenin 2
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPR2 natriuretic peptide receptor 2
NPR3 natriuretic peptide receptor 3
PAX5 paired box 5
PCGF3 polycomb group ring finger 3
PEX5 peroxisomal biogenesis factor 5
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PLK4 polo-like kinase 4
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PRB1 proline-rich protein BstNI subfamily 1
PRDX2 peroxiredoxin 2
PROL1 proline rich, lacrimal 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RIMBP2 RIMS binding protein 2
RPGR retinitis pigmentosa GTPase regulator
RPS14 ribosomal protein S14
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
SAP30 Sin3A-associated protein, 30kDa
SDC3 syndecan 3
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC39A9 solute carrier family 39, member 9
SLC45A2 solute carrier family 45, member 2
SOAT2 sterol O-acyltransferase 2
SORBS3 sorbin and SH3 domain containing 3
SPAG8 sperm associated antigen 8
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SSPN sarcospan
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STXBP6 syntaxin binding protein 6 (amisyn)
TAPBPL TAP binding protein-like
THSD7A thrombospondin, type I, domain containing 7A
TMPRSS3 transmembrane protease, serine 3
TPMT thiopurine S-methyltransferase
TRIM2 tripartite motif containing 2
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPV4 transient receptor potential cation channel, subfamily V, member 4
WDR55 WD repeat domain 55
XDH xanthine dehydrogenase
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF329 zinc finger protein 329
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
AES amino-terminal enhancer of split
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ARHGAP19 Rho GTPase activating protein 19
BCL9 B-cell CLL/lymphoma 9
C14ORF132 chromosome 14 open reading frame 132
CADPS2 Ca++-dependent secretion activator 2
CAMKMT calmodulin-lysine N-methyltransferase
CCNO cyclin O
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDK3 cyclin-dependent kinase 3
CEP131 centrosomal protein 131kDa
CHKB choline kinase beta
CIDEC cell death-inducing DFFA-like effector c
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COCH cochlin
CRYL1 crystallin, lambda 1
CSK c-src tyrosine kinase
CTDNEP1 CTD nuclear envelope phosphatase 1
DAAM1 dishevelled associated activator of morphogenesis 1
EIF5A2 eukaryotic translation initiation factor 5A2
ELMO3 engulfment and cell motility 3
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPPK1 epiplakin 1
FAM160B2 family with sequence similarity 160, member B2
FAN1 FANCD2/FANCI-associated nuclease 1
FBXO3 F-box protein 3
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FKBP14 FK506 binding protein 14, 22 kDa
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
FZD2 frizzled class receptor 2
H2AFJ H2A histone family, member J
HIRA histone cell cycle regulator
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IGFLR1 IGF-like family receptor 1
IL15RA interleukin 15 receptor, alpha
IREB2 iron-responsive element binding protein 2
IRX4 iroquois homeobox 4
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0556 KIAA0556
KLF11 Kruppel-like factor 11
LAMA3 laminin, alpha 3
LHX6 LIM homeobox 6
LIN7B lin-7 homolog B (C. elegans)
LNPEP leucyl/cystinyl aminopeptidase
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRRC20 leucine rich repeat containing 20
LYPD1 LY6/PLAUR domain containing 1
MANBA mannosidase, beta A, lysosomal
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAST3 microtubule associated serine/threonine kinase 3
MB myoglobin
MCOLN3 mucolipin 3
MEX3C mex-3 RNA binding family member C
MORC3 MORC family CW-type zinc finger 3
MXD3 MAX dimerization protein 3
NCAM2 neural cell adhesion molecule 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NUPL2 nucleoporin like 2
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
ORAI3 ORAI calcium release-activated calcium modulator 3
PAQR3 progestin and adipoQ receptor family member III
PDE12 phosphodiesterase 12
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLD2 phospholipase D2
PLEC plectin
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
PP14571 uncharacterized LOC100130449
RAB5B RAB5B, member RAS oncogene family
RASAL1 RAS protein activator like 1 (GAP1 like)
RBL1 retinoblastoma-like 1
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF31 ring finger protein 31
SCAI suppressor of cancer cell invasion
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SCUBE2 signal peptide, CUB domain, EGF-like 2
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SETD8 SET domain containing (lysine methyltransferase) 8
SGMS1 sphingomyelin synthase 1
SIK1 salt-inducible kinase 1
SIRT6 sirtuin 6
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC38A10 solute carrier family 38, member 10
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TM7SF3 transmembrane 7 superfamily member 3
TMC5 transmembrane channel-like 5
TRAF2 TNF receptor-associated factor 2
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TUBGCP5 tubulin, gamma complex associated protein 5
TXLNA taxilin alpha
XYLT2 xylosyltransferase II
ZFAND3 zinc finger, AN1-type domain 3
ZMYM1 zinc finger, MYM-type 1
ZNF205 zinc finger protein 205
ZNF586 zinc finger protein 586
ZNF652 zinc finger protein 652