| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the prilocaine-2352 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AGGF1 | angiogenic factor with G patch and FHA domains 1 |
| AMT | aminomethyltransferase |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APOM | apolipoprotein M |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| BCL2 | B-cell CLL/lymphoma 2 |
| BTBD7 | BTB (POZ) domain containing 7 |
| C9ORF156 | chromosome 9 open reading frame 156 |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CD300C | CD300c molecule |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 |
| CHST4 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
| CLDN15 | claudin 15 |
| COL7A1 | collagen, type VII, alpha 1 |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DRG2 | developmentally regulated GTP binding protein 2 |
| DUSP4 | dual specificity phosphatase 4 |
| ECI2 | enoyl-CoA delta isomerase 2 |
| FAM63A | family with sequence similarity 63, member A |
| FASTKD5 | FAST kinase domains 5 |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
| FOXG1 | forkhead box G1 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GATA2 | GATA binding protein 2 |
| GEMIN4 | gem (nuclear organelle) associated protein 4 |
| GK | glycerol kinase |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GPX2 | glutathione peroxidase 2 |
| GSPT1 | G1 to S phase transition 1 |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H4D | histone cluster 1, H4d |
| HOXA10 | homeobox A10 |
| HOXB7 | homeobox B7 |
| HSPG2 | heparan sulfate proteoglycan 2 |
| IL13RA1 | interleukin 13 receptor, alpha 1 |
| IQCK | IQ motif containing K |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
| KIAA0753 | KIAA0753 |
| KIF13B | kinesin family member 13B |
| LAMC3 | laminin, gamma 3 |
| LPPR3 | lipid phosphate phosphatase-related protein type 3 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MAPT | microtubule-associated protein tau |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MAX | MYC associated factor X |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MDFI | MyoD family inhibitor |
| MDM4 | MDM4, p53 regulator |
| MECP2 | methyl CpG binding protein 2 |
| MED25 | mediator complex subunit 25 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PARG | poly (ADP-ribose) glycohydrolase |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PDLIM5 | PDZ and LIM domain 5 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLSCR3 | phospholipid scramblase 3 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PTCRA | pre T-cell antigen receptor alpha |
| RET | ret proto-oncogene |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RUNX1 | runt-related transcription factor 1 |
| SCAMP1 | secretory carrier membrane protein 1 |
| SCLY | selenocysteine lyase |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMAD5 | SMAD family member 5 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SQSTM1 | sequestosome 1 |
| SRR | serine racemase |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
| TAOK2 | TAO kinase 2 |
| TBCD | tubulin folding cofactor D |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TMEM63A | transmembrane protein 63A |
| TNFRSF4 | tumor necrosis factor receptor superfamily, member 4 |
| TOP3B | topoisomerase (DNA) III beta |
| TPM2 | tropomyosin 2 (beta) |
| TRIM58 | tripartite motif containing 58 |
| UHRF1BP1L | UHRF1 binding protein 1-like |
| USB1 | U6 snRNA biogenesis 1 |
| VPS45 | vacuolar protein sorting 45 homolog (S. cerevisiae) |
| VWA5A | von Willebrand factor A domain containing 5A |
| ZNF354A | zinc finger protein 354A |
| Symbol | Name |
|---|---|
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 |
| ABHD17B | abhydrolase domain containing 17B |
| AGO4 | argonaute RISC catalytic component 4 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATF3 | activating transcription factor 3 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BBS10 | Bardet-Biedl syndrome 10 |
| BIN3 | bridging integrator 3 |
| C11ORF21 | chromosome 11 open reading frame 21 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| CCDC15 | coiled-coil domain containing 15 |
| CD1D | CD1d molecule |
| CDK6 | cyclin-dependent kinase 6 |
| CEP131 | centrosomal protein 131kDa |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CLEC7A | C-type lectin domain family 7, member A |
| DBF4B | DBF4 zinc finger B |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| DNA2 | DNA replication helicase/nuclease 2 |
| DSPP | dentin sialophosphoprotein |
| EFHC1 | EF-hand domain (C-terminal) containing 1 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| FAM188A | family with sequence similarity 188, member A |
| FILIP1L | filamin A interacting protein 1-like |
| GAB2 | GRB2-associated binding protein 2 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 |
| GPATCH3 | G patch domain containing 3 |
| GPR27 | G protein-coupled receptor 27 |
| GRAMD1B | GRAM domain containing 1B |
| HIST1H2BF | histone cluster 1, H2bf |
| HIST2H2BE | histone cluster 2, H2be |
| HIST3H2A | histone cluster 3, H2a |
| HOOK2 | hook microtubule-tethering protein 2 |
| HS1BP3 | HCLS1 binding protein 3 |
| IRF2 | interferon regulatory factor 2 |
| ITGAV | integrin, alpha V |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KLK5 | kallikrein-related peptidase 5 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LRRC20 | leucine rich repeat containing 20 |
| MANBA | mannosidase, beta A, lysosomal |
| MAP3K3 | mitogen-activated protein kinase kinase kinase 3 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MLPH | melanophilin |
| MON1B | MON1 secretory trafficking family member B |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NAG18 | NAG18 mRNA |
| NBEAL2 | neurobeachin-like 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| OCEL1 | occludin/ELL domain containing 1 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PJA1 | praja ring finger 1, E3 ubiquitin protein ligase |
| PMCH | pro-melanin-concentrating hormone |
| PNMA1 | paraneoplastic Ma antigen 1 |
| POLM | polymerase (DNA directed), mu |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PRAF2 | PRA1 domain family, member 2 |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| QPCT | glutaminyl-peptide cyclotransferase |
| RAB33B | RAB33B, member RAS oncogene family |
| RCAN3 | RCAN family member 3 |
| RFXAP | regulatory factor X-associated protein |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF144A | ring finger protein 144A |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| S1PR4 | sphingosine-1-phosphate receptor 4 |
| SDF2 | stromal cell-derived factor 2 |
| SETD1A | SET domain containing 1A |
| SHARPIN | SHANK-associated RH domain interactor |
| SMA4 | glucuronidase, beta pseudogene |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SP140L | SP140 nuclear body protein-like |
| SPATA2L | spermatogenesis associated 2-like |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
| STAG3 | stromal antigen 3 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| STX17 | syntaxin 17 |
| TBX19 | T-box 19 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMEM184B | transmembrane protein 184B |
| TNRC6B | trinucleotide repeat containing 6B |
| TPK1 | thiamin pyrophosphokinase 1 |
| TRIM5 | tripartite motif containing 5 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UBQLN4 | ubiquilin 4 |
| WWC2 | WW and C2 domain containing 2 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF580 | zinc finger protein 580 |
| ZNF767P | zinc finger family member 767, pseudogene |