prilocaine-2352 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the prilocaine-2352 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AGGF1 angiogenic factor with G patch and FHA domains 1
AMT aminomethyltransferase
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APOM apolipoprotein M
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
BCL2 B-cell CLL/lymphoma 2
BTBD7 BTB (POZ) domain containing 7
C9ORF156 chromosome 9 open reading frame 156
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CD300C CD300c molecule
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CLDN15 claudin 15
COL7A1 collagen, type VII, alpha 1
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DRG2 developmentally regulated GTP binding protein 2
DUSP4 dual specificity phosphatase 4
ECI2 enoyl-CoA delta isomerase 2
FAM63A family with sequence similarity 63, member A
FASTKD5 FAST kinase domains 5
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FOXG1 forkhead box G1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GATA2 GATA binding protein 2
GEMIN4 gem (nuclear organelle) associated protein 4
GK glycerol kinase
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GPX2 glutathione peroxidase 2
GSPT1 G1 to S phase transition 1
HIST1H2BG histone cluster 1, H2bg
HIST1H4D histone cluster 1, H4d
HOXA10 homeobox A10
HOXB7 homeobox B7
HSPG2 heparan sulfate proteoglycan 2
IL13RA1 interleukin 13 receptor, alpha 1
IQCK IQ motif containing K
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KIAA0753 KIAA0753
KIF13B kinesin family member 13B
LAMC3 laminin, gamma 3
LPPR3 lipid phosphate phosphatase-related protein type 3
LRP2 low density lipoprotein receptor-related protein 2
LTB lymphotoxin beta (TNF superfamily, member 3)
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAPT microtubule-associated protein tau
MARK4 MAP/microtubule affinity-regulating kinase 4
MAX MYC associated factor X
MBTPS2 membrane-bound transcription factor peptidase, site 2
MDFI MyoD family inhibitor
MDM4 MDM4, p53 regulator
MECP2 methyl CpG binding protein 2
MED25 mediator complex subunit 25
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NPM3 nucleophosmin/nucleoplasmin 3
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PARG poly (ADP-ribose) glycohydrolase
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDLIM5 PDZ and LIM domain 5
PDLIM7 PDZ and LIM domain 7 (enigma)
PHC1 polyhomeotic homolog 1 (Drosophila)
PLSCR3 phospholipid scramblase 3
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
PRICKLE3 prickle homolog 3 (Drosophila)
PTCRA pre T-cell antigen receptor alpha
RET ret proto-oncogene
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RUNX1 runt-related transcription factor 1
SCAMP1 secretory carrier membrane protein 1
SCLY selenocysteine lyase
SCUBE3 signal peptide, CUB domain, EGF-like 3
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMAD5 SMAD family member 5
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOX4 SRY (sex determining region Y)-box 4
SQSTM1 sequestosome 1
SRR serine racemase
ST3GAL6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6
TAOK2 TAO kinase 2
TBCD tubulin folding cofactor D
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TMEM63A transmembrane protein 63A
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TOP3B topoisomerase (DNA) III beta
TPM2 tropomyosin 2 (beta)
TRIM58 tripartite motif containing 58
UHRF1BP1L UHRF1 binding protein 1-like
USB1 U6 snRNA biogenesis 1
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)
VWA5A von Willebrand factor A domain containing 5A
ZNF354A zinc finger protein 354A

decreased expression

Symbol Name
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ABHD17B abhydrolase domain containing 17B
AGO4 argonaute RISC catalytic component 4
AHDC1 AT hook, DNA binding motif, containing 1
ALG12 ALG12, alpha-1,6-mannosyltransferase
ATAD5 ATPase family, AAA domain containing 5
ATF3 activating transcription factor 3
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BBS10 Bardet-Biedl syndrome 10
BIN3 bridging integrator 3
C11ORF21 chromosome 11 open reading frame 21
C19ORF40 chromosome 19 open reading frame 40
CCDC15 coiled-coil domain containing 15
CD1D CD1d molecule
CDK6 cyclin-dependent kinase 6
CEP131 centrosomal protein 131kDa
CIR1 corepressor interacting with RBPJ, 1
CLEC7A C-type lectin domain family 7, member A
DBF4B DBF4 zinc finger B
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNA2 DNA replication helicase/nuclease 2
DSPP dentin sialophosphoprotein
EFHC1 EF-hand domain (C-terminal) containing 1
ELP6 elongator acetyltransferase complex subunit 6
FAM188A family with sequence similarity 188, member A
FILIP1L filamin A interacting protein 1-like
GAB2 GRB2-associated binding protein 2
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPATCH3 G patch domain containing 3
GPR27 G protein-coupled receptor 27
GRAMD1B GRAM domain containing 1B
HIST1H2BF histone cluster 1, H2bf
HIST2H2BE histone cluster 2, H2be
HIST3H2A histone cluster 3, H2a
HOOK2 hook microtubule-tethering protein 2
HS1BP3 HCLS1 binding protein 3
IRF2 interferon regulatory factor 2
ITGAV integrin, alpha V
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KLK5 kallikrein-related peptidase 5
KRI1 KRI1 homolog (S. cerevisiae)
LRRC20 leucine rich repeat containing 20
MANBA mannosidase, beta A, lysosomal
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAPKBP1 mitogen-activated protein kinase binding protein 1
MAST3 microtubule associated serine/threonine kinase 3
MLPH melanophilin
MON1B MON1 secretory trafficking family member B
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NAG18 NAG18 mRNA
NBEAL2 neurobeachin-like 2
NPFFR1 neuropeptide FF receptor 1
OCEL1 occludin/ELL domain containing 1
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
PMCH pro-melanin-concentrating hormone
PNMA1 paraneoplastic Ma antigen 1
POLM polymerase (DNA directed), mu
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PRAF2 PRA1 domain family, member 2
PWAR5 Prader Willi/Angelman region RNA 5
QPCT glutaminyl-peptide cyclotransferase
RAB33B RAB33B, member RAS oncogene family
RCAN3 RCAN family member 3
RFXAP regulatory factor X-associated protein
RHOBTB1 Rho-related BTB domain containing 1
RNF126P1 ring finger protein 126 pseudogene 1
RNF144A ring finger protein 144A
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
S1PR4 sphingosine-1-phosphate receptor 4
SDF2 stromal cell-derived factor 2
SETD1A SET domain containing 1A
SHARPIN SHANK-associated RH domain interactor
SMA4 glucuronidase, beta pseudogene
SMR3A submaxillary gland androgen regulated protein 3A
SP140L SP140 nuclear body protein-like
SPATA2L spermatogenesis associated 2-like
SRD5A3 steroid 5 alpha-reductase 3
ST6GALNAC4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
STAG3 stromal antigen 3
STEAP1 six transmembrane epithelial antigen of the prostate 1
STX17 syntaxin 17
TBX19 T-box 19
TET3 tet methylcytosine dioxygenase 3
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM184B transmembrane protein 184B
TNRC6B trinucleotide repeat containing 6B
TPK1 thiamin pyrophosphokinase 1
TRIM5 tripartite motif containing 5
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBQLN4 ubiquilin 4
WWC2 WW and C2 domain containing 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF580 zinc finger protein 580
ZNF767P zinc finger family member 767, pseudogene