prilocaine-3624 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the prilocaine-3624 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACO2 aconitase 2, mitochondrial
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ADAM28 ADAM metallopeptidase domain 28
ARC activity-regulated cytoskeleton-associated protein
BAIAP3 BAI1-associated protein 3
C14ORF79 chromosome 14 open reading frame 79
CA1 carbonic anhydrase I
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD22 CD22 molecule
CD4 CD4 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CEP41 centrosomal protein 41kDa
CLEC1A C-type lectin domain family 1, member A
COL6A1 collagen, type VI, alpha 1
CTBP2 C-terminal binding protein 2
CTGF connective tissue growth factor
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A7 cytochrome P450, family 3, subfamily A, polypeptide 7
DBF4B DBF4 zinc finger B
DEFA4 defensin, alpha 4, corticostatin
DLK2 delta-like 2 homolog (Drosophila)
DPY19L1 dpy-19-like 1 (C. elegans)
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EFR3B EFR3 homolog B (S. cerevisiae)
ELF5 E74-like factor 5 (ets domain transcription factor)
ELP6 elongator acetyltransferase complex subunit 6
EPHB6 EPH receptor B6
EXOSC1 exosome component 1
FLRT2 fibronectin leucine rich transmembrane protein 2
FN1 fibronectin 1
FYB FYN binding protein
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GJA4 gap junction protein, alpha 4, 37kDa
GPER1 G protein-coupled estrogen receptor 1
HEXA-AS1 HEXA antisense RNA 1
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HYAL3 hyaluronoglucosaminidase 3
IGF1R insulin-like growth factor 1 receptor
IGLJ3 immunoglobulin lambda joining 3
ITGA7 integrin, alpha 7
KIAA1109 KIAA1109
KLF13 Kruppel-like factor 13
KLHL25 kelch-like family member 25
KRT2 keratin 2, type II
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LECT1 leukocyte cell derived chemotaxin 1
LOC399491
LPAR1 lysophosphatidic acid receptor 1
LRRC37A3 leucine rich repeat containing 37, member A3
LTC4S leukotriene C4 synthase
MAP4 microtubule-associated protein 4
MKL1 megakaryoblastic leukemia (translocation) 1
MPP1 membrane protein, palmitoylated 1, 55kDa
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MUC5B mucin 5B, oligomeric mucus/gel-forming
NOP14-AS1 NOP14 antisense RNA 1
NPFF neuropeptide FF-amide peptide precursor
NR4A1 nuclear receptor subfamily 4, group A, member 1
OGDHL oxoglutarate dehydrogenase-like
OPCML opioid binding protein/cell adhesion molecule-like
PARVB parvin, beta
PDGFC platelet derived growth factor C
PLIN2 perilipin 2
PLVAP plasmalemma vesicle associated protein
POU5F1B POU class 5 homeobox 1B
PTK2B protein tyrosine kinase 2 beta
RND2 Rho family GTPase 2
RPS4Y1 ribosomal protein S4, Y-linked 1
RTCA RNA 3'-terminal phosphate cyclase
RUFY2 RUN and FYVE domain containing 2
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
SCAND2P SCAN domain containing 2 pseudogene
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIPA1 signal-induced proliferation-associated 1
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC14A2 solute carrier family 14 (urea transporter), member 2
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SPDEF SAM pointed domain containing ETS transcription factor
SPHK2 sphingosine kinase 2
SRGAP3 SLIT-ROBO Rho GTPase activating protein 3
SSBP1 single-stranded DNA binding protein 1, mitochondrial
SULT4A1 sulfotransferase family 4A, member 1
SZT2 seizure threshold 2 homolog (mouse)
TCEAL2 transcription elongation factor A (SII)-like 2
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TGFA transforming growth factor, alpha
TMOD1 tropomodulin 1
TRIM10 tripartite motif containing 10
TRIP6 thyroid hormone receptor interactor 6
TSC2 tuberous sclerosis 2
TTC39A tetratricopeptide repeat domain 39A
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
ZNF362 zinc finger protein 362
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ADAM15 ADAM metallopeptidase domain 15
ADGRE5 adhesion G protein-coupled receptor E5
ALOX15 arachidonate 15-lipoxygenase
ANKFY1 ankyrin repeat and FYVE domain containing 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATAD5 ATPase family, AAA domain containing 5
BAHCC1 BAH domain and coiled-coil containing 1
BSG basigin (Ok blood group)
BTBD2 BTB (POZ) domain containing 2
C11ORF80 chromosome 11 open reading frame 80
C1ORF105 chromosome 1 open reading frame 105
C8ORF44 chromosome 8 open reading frame 44
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CD3D CD3d molecule, delta (CD3-TCR complex)
CDC37 cell division cycle 37
CDK3 cyclin-dependent kinase 3
CDK6 cyclin-dependent kinase 6
CEP72 centrosomal protein 72kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLSTN2 calsyntenin 2
CNTN1 contactin 1
CORT cortistatin
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
EFNA3 ephrin-A3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPN1 epsin 1
ERF Ets2 repressor factor
F2R coagulation factor II (thrombin) receptor
FAM155A family with sequence similarity 155, member A
FAM212B family with sequence similarity 212, member B
FKBP5 FK506 binding protein 5
FRK fyn-related Src family tyrosine kinase
FUZ fuzzy planar cell polarity protein
GTF2I general transcription factor IIi
HIST2H2AA3 histone cluster 2, H2aa3
HMOX1 heme oxygenase 1
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JMJD4 jumonji domain containing 4
KCTD20 potassium channel tetramerization domain containing 20
KCTD7 potassium channel tetramerization domain containing 7
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KITLG KIT ligand
LMCD1 LIM and cysteine-rich domains 1
LNPEP leucyl/cystinyl aminopeptidase
LOXL3 lysyl oxidase-like 3
LPXN leupaxin
MCC mutated in colorectal cancers
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MITF microphthalmia-associated transcription factor
MOB3B MOB kinase activator 3B
MPDU1 mannose-P-dolichol utilization defect 1
MTA2 metastasis associated 1 family, member 2
MUL1 mitochondrial E3 ubiquitin protein ligase 1
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLD2 phospholipase D2
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPAP2C phosphatidic acid phosphatase type 2C
PRR4 proline rich 4 (lacrimal)
PSENEN presenilin enhancer gamma secretase subunit
QPCTL glutaminyl-peptide cyclotransferase-like
QTRT1 queuine tRNA-ribosyltransferase 1
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RGS17 regulator of G-protein signaling 17
RGS2 regulator of G-protein signaling 2
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF208 ring finger protein 208
SCGB2A2 secretoglobin, family 2A, member 2
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SH3GLB2 SH3-domain GRB2-like endophilin B2
SIX1 SIX homeobox 1
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SYTL2 synaptotagmin-like 2
TBC1D19 TBC1 domain family, member 19
TESK2 testis-specific kinase 2
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TMEM209 transmembrane protein 209
TMEM53 transmembrane protein 53
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TSPAN1 tetraspanin 1
USB1 U6 snRNA biogenesis 1
USP20 ubiquitin specific peptidase 20
USP27X ubiquitin specific peptidase 27, X-linked
VAX2 ventral anterior homeobox 2
VIPR1 vasoactive intestinal peptide receptor 1
XDH xanthine dehydrogenase
YY2 YY2 transcription factor
ZBTB48 zinc finger and BTB domain containing 48
ZMAT5 zinc finger, matrin-type 5