prilocaine-3727 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the prilocaine-3727 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADD2 adducin 2 (beta)
ADGRA2 adhesion G protein-coupled receptor A2
ANKRD12 ankyrin repeat domain 12
AP2B1 adaptor-related protein complex 2, beta 1 subunit
APLP2 amyloid beta (A4) precursor-like protein 2
APP amyloid beta (A4) precursor protein
ATP11A ATPase, class VI, type 11A
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
AURKA aurora kinase A
BMP1 bone morphogenetic protein 1
BMP8B bone morphogenetic protein 8b
C22ORF24 chromosome 22 open reading frame 24
CADM4 cell adhesion molecule 4
CCIN calicin
CD58 CD58 molecule
CFAP70 cilia and flagella associated protein 70
CLCN4 chloride channel, voltage-sensitive 4
COPZ2 coatomer protein complex, subunit zeta 2
CRAT carnitine O-acetyltransferase
DHRS7 dehydrogenase/reductase (SDR family) member 7
ECM2 extracellular matrix protein 2, female organ and adipocyte specific
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1
EGR1 early growth response 1
EIF5B eukaryotic translation initiation factor 5B
EZR ezrin
FBXO21 F-box protein 21
FGFR2 fibroblast growth factor receptor 2
GPATCH4 G patch domain containing 4
GPD2 glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
GPM6B glycoprotein M6B
GRSF1 G-rich RNA sequence binding factor 1
GTPBP1 GTP binding protein 1
GUK1 guanylate kinase 1
HAB1 B1 for mucin
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
ING2 inhibitor of growth family, member 2
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KIAA0040 KIAA0040
KRT7 keratin 7, type II
LIMK2 LIM domain kinase 2
MIER2 mesoderm induction early response 1, family member 2
MST1 macrophage stimulating 1
MST1L macrophage stimulating 1-like
NCKAP1 NCK-associated protein 1
NOP14-AS1 NOP14 antisense RNA 1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOTCH4 notch 4
NPM3 nucleophosmin/nucleoplasmin 3
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
OAZ3 ornithine decarboxylase antizyme 3
OSGIN2 oxidative stress induced growth inhibitor family member 2
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PDCD2 programmed cell death 2
PDE2A phosphodiesterase 2A, cGMP-stimulated
PEX26 peroxisomal biogenesis factor 26
PGK1 phosphoglycerate kinase 1
PLXNC1 plexin C1
PLXND1 plexin D1
PMCH pro-melanin-concentrating hormone
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PRRC2C proline-rich coiled-coil 2C
PTCRA pre T-cell antigen receptor alpha
RAB2A RAB2A, member RAS oncogene family
RABGAP1L RAB GTPase activating protein 1-like
RAD23B RAD23 homolog B (S. cerevisiae)
RGS4 regulator of G-protein signaling 4
RHEB Ras homolog enriched in brain
RNF146 ring finger protein 146
RPAIN RPA interacting protein
RPL14 ribosomal protein L14
RPL35A ribosomal protein L35a
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPLP2 ribosomal protein, large, P2
RUNX1 runt-related transcription factor 1
SERHL2 serine hydrolase-like 2
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SRR serine racemase
STAT4 signal transducer and activator of transcription 4
STK16 serine/threonine kinase 16
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TET3 tet methylcytosine dioxygenase 3
TM6SF1 transmembrane 6 superfamily member 1
TMCO6 transmembrane and coiled-coil domains 6
TMED9 transmembrane emp24 protein transport domain containing 9
TRAM1 translocation associated membrane protein 1
TWF1 twinfilin actin binding protein 1
TXN thioredoxin
UBE2I ubiquitin-conjugating enzyme E2I
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VDAC3 voltage-dependent anion channel 3
YY1 YY1 transcription factor
ZMYND8 zinc finger, MYND-type containing 8
ZNF280B zinc finger protein 280B

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADGRB2 adhesion G protein-coupled receptor B2
ADTRP androgen-dependent TFPI-regulating protein
AHSG alpha-2-HS-glycoprotein
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AK5 adenylate kinase 5
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARMCX4 armadillo repeat containing, X-linked 4
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
CCDC71 coiled-coil domain containing 71
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD82 CD82 molecule
CDH19 cadherin 19, type 2
CEP41 centrosomal protein 41kDa
CES3 carboxylesterase 3
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLCA1 chloride channel accessory 1
CLSTN3 calsyntenin 3
CNPY4 canopy FGF signaling regulator 4
CORT cortistatin
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CYB5R2 cytochrome b5 reductase 2
CYBRD1 cytochrome b reductase 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DMTN dematin actin binding protein
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DOK5 docking protein 5
DSPP dentin sialophosphoprotein
DYM dymeclin
EGF epidermal growth factor
ERF Ets2 repressor factor
FAM120C family with sequence similarity 120C
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
GLB1L galactosidase, beta 1-like
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GTF2A1 general transcription factor IIA, 1, 19/37kDa
H2AFJ H2A histone family, member J
HIST1H2BM histone cluster 1, H2bm
HIST1H3B histone cluster 1, H3b
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-DMA major histocompatibility complex, class II, DM alpha
HOXA7 homeobox A7
HPN hepsin
IFT22 intraflagellar transport 22
IQSEC2 IQ motif and Sec7 domain 2
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KIAA0754 KIAA0754
KLHL29 kelch-like family member 29
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LIPG lipase, endothelial
LMTK1 lemur tail kinase 1
LPPR1 lipid phosphate phosphatase-related protein type 1
LRP3 low density lipoprotein receptor-related protein 3
LRRC15 leucine rich repeat containing 15
LY6G5C lymphocyte antigen 6 complex, locus G5C
MAPK12 mitogen-activated protein kinase 12
MBNL3 muscleblind-like splicing regulator 3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MXD3 MAX dimerization protein 3
NARFL nuclear prelamin A recognition factor-like
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NPHP1 nephronophthisis 1 (juvenile)
OLFML2A olfactomedin-like 2A
PRR4 proline rich 4 (lacrimal)
PRSS16 protease, serine, 16 (thymus)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RUSC2 RUN and SH3 domain containing 2
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLN sarcolipin
SREBF1 sterol regulatory element binding transcription factor 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TAOK1 TAO kinase 1
TBC1D2 TBC1 domain family, member 2
TEP1 telomerase-associated protein 1
TESPA1 thymocyte expressed, positive selection associated 1
TEX15 testis expressed 15
TIGD6 tigger transposable element derived 6
TRMT44 tRNA methyltransferase 44 homolog (S. cerevisiae)
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSNAXIP1 translin-associated factor X interacting protein 1
TUBB2B tubulin, beta 2B class IIb
VEZT vezatin, adherens junctions transmembrane protein
VGLL3 vestigial-like family member 3
VLDLR very low density lipoprotein receptor
WNT7A wingless-type MMTV integration site family, member 7A
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF134 zinc finger protein 134
ZNF516 zinc finger protein 516
ZNF702P zinc finger protein 702, pseudogene
ZNF76 zinc finger protein 76