prilocaine-4284 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the prilocaine-4284 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACVR1B activin A receptor, type IB
ADAM19 ADAM metallopeptidase domain 19
ADIPOQ adiponectin, C1Q and collagen domain containing
AGTR1 angiotensin II receptor, type 1
AMELY amelogenin, Y-linked
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BMP7 bone morphogenetic protein 7
BTK Bruton agammaglobulinemia tyrosine kinase
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C5AR1 complement component 5a receptor 1
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CCL22 chemokine (C-C motif) ligand 22
CD209 CD209 molecule
CD38 CD38 molecule
CD53 CD53 molecule
CD6 CD6 molecule
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLEC4M C-type lectin domain family 4, member M
CLPS colipase, pancreatic
CRYGD crystallin, gamma D
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DBT dihydrolipoamide branched chain transacylase E2
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
E2F5 E2F transcription factor 5, p130-binding
EDRF1 erythroid differentiation regulatory factor 1
F9 coagulation factor IX
FGL2 fibrinogen-like 2
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLJ11292
FYB FYN binding protein
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GAS7 growth arrest-specific 7
GRIK5 glutamate receptor, ionotropic, kainate 5
HEXA hexosaminidase A (alpha polypeptide)
HIST1H1D histone cluster 1, H1d
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HNF1B HNF1 homeobox B
HNF4A hepatocyte nuclear factor 4, alpha
HTN1 histatin 1
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL21R interleukin 21 receptor
IL2RA interleukin 2 receptor, alpha
IL33R interleukin 33 receptor
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IRF4 interferon regulatory factor 4
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KIAA0040 KIAA0040
KIAA0226L KIAA0226-like
KITLG KIT ligand
MCF2L MCF.2 cell line derived transforming sequence-like
MMP28 matrix metallopeptidase 28
MYH14 myosin, heavy chain 14, non-muscle
MYH2 myosin, heavy chain 2, skeletal muscle, adult
NPTX2 neuronal pentraxin II
NR4A1 nuclear receptor subfamily 4, group A, member 1
NTF3 neurotrophin 3
NTS neurotensin
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PCDHB12 protocadherin beta 12
PCSK1 proprotein convertase subtilisin/kexin type 1
PCSK6 proprotein convertase subtilisin/kexin type 6
PEX3 peroxisomal biogenesis factor 3
PLD1 phospholipase D1, phosphatidylcholine-specific
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
POU4F2 POU class 4 homeobox 2
PRDM14 PR domain containing 14
PRKG1 protein kinase, cGMP-dependent, type I
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAB2A RAB2A, member RAS oncogene family
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RBM34 RNA binding motif protein 34
RIBC2 RIB43A domain with coiled-coils 2
RNF17 ring finger protein 17
RORA RAR-related orphan receptor A
RPS4Y1 ribosomal protein S4, Y-linked 1
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
SAA4 serum amyloid A4, constitutive
SARDH sarcosine dehydrogenase
SCN10A sodium channel, voltage gated, type X alpha subunit
SH3GL3 SH3-domain GRB2-like 3
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SNX29P2 sorting nexin 29 pseudogene 2
SSX1 synovial sarcoma, X breakpoint 1
TAAR2 trace amine associated receptor 2
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAT tyrosine aminotransferase
TBR1 T-box, brain, 1
TMEM143 transmembrane protein 143
TP53I11 tumor protein p53 inducible protein 11
TRIM10 tripartite motif containing 10
TSC22D2 TSC22 domain family, member 2
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)
XIST X inactive specific transcript (non-protein coding)
ZNF407 zinc finger protein 407
ZNF614 zinc finger protein 614
ZNF780B zinc finger protein 780B

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ALPK1 alpha-kinase 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARRB2 arrestin, beta 2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCAS3 breast carcinoma amplified sequence 3
BCORL1 BCL6 corepressor-like 1
C1QTNF1 C1q and tumor necrosis factor related protein 1
C4ORF29 chromosome 4 open reading frame 29
C5 complement component 5
CA5BP1 carbonic anhydrase VB pseudogene 1
CCDC106 coiled-coil domain containing 106
CCDC25 coiled-coil domain containing 25
CEMIP cell migration inducing protein, hyaluronan binding
CHMP7 charged multivesicular body protein 7
CHPF chondroitin polymerizing factor
CTNNBL1 catenin, beta like 1
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DGKZ diacylglycerol kinase, zeta
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM204A family with sequence similarity 204, member A
FANCC Fanconi anemia, complementation group C
FMO4 flavin containing monooxygenase 4
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HDAC5 histone deacetylase 5
HELZ helicase with zinc finger
HOXC13 homeobox C13
IL17RA interleukin 17 receptor A
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA1549L KIAA1549-like
KLHL36 kelch-like family member 36
KRT75 keratin 75, type II
LMNB1 lamin B1
LRRC37A3 leucine rich repeat containing 37, member A3
LY6E lymphocyte antigen 6 complex, locus E
LZTR1 leucine-zipper-like transcription regulator 1
MAPK12 mitogen-activated protein kinase 12
MDFI MyoD family inhibitor
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MOGS mannosyl-oligosaccharide glucosidase
MON1B MON1 secretory trafficking family member B
MRPL44 mitochondrial ribosomal protein L44
NBEAL2 neurobeachin-like 2
NDRG4 NDRG family member 4
NRSN2 neurensin 2
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OSMR oncostatin M receptor
OVGP1 oviductal glycoprotein 1, 120kDa
PALB2 partner and localizer of BRCA2
PDE12 phosphodiesterase 12
PER3 period circadian clock 3
PHACTR4 phosphatase and actin regulator 4
PHC1 polyhomeotic homolog 1 (Drosophila)
PHF14 PHD finger protein 14
PIEZO1 piezo-type mechanosensitive ion channel component 1
PLD2 phospholipase D2
PRKX protein kinase, X-linked
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RBM15B RNA binding motif protein 15B
RBM42 RNA binding motif protein 42
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RPAP1 RNA polymerase II associated protein 1
SDC3 syndecan 3
SETBP1 SET binding protein 1
SH3TC2 SH3 domain and tetratricopeptide repeats 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STX17 syntaxin 17
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAGLN3 transgelin 3
TESK2 testis-specific kinase 2
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TLN1 talin 1
TMEM121 transmembrane protein 121
TOR4A torsin family 4, member A
TROAP trophinin associated protein
TTC31 tetratricopeptide repeat domain 31
UNC119 unc-119 homolog (C. elegans)
USP18 ubiquitin specific peptidase 18
WASF2 WAS protein family, member 2
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
YY2 YY2 transcription factor
ZHX2 zinc fingers and homeoboxes 2
ZMAT5 zinc finger, matrin-type 5
ZNF264 zinc finger protein 264
ZNF652 zinc finger protein 652
ZNF778 zinc finger protein 778
ZSCAN5A zinc finger and SCAN domain containing 5A