prilocaine-4749 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the prilocaine-4749 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTC1 actin, alpha, cardiac muscle 1
ADRBK1 adrenergic, beta, receptor kinase 1
AKAP5 A kinase (PRKA) anchor protein 5
ALK anaplastic lymphoma receptor tyrosine kinase
AMPH amphiphysin
ANXA2P1 annexin A2 pseudogene 1
ATG10 autophagy related 10
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCDC64 coiled-coil domain containing 64
CCKAR cholecystokinin A receptor
CCT8L2 chaperonin containing TCP1, subunit 8 (theta)-like 2
CD22 CD22 molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CIDEB cell death-inducing DFFA-like effector b
CLSTN3 calsyntenin 3
COL6A1 collagen, type VI, alpha 1
CTBP2 C-terminal binding protein 2
CTNS cystinosin, lysosomal cystine transporter
DMRT1 doublesex and mab-3 related transcription factor 1
DTNB dystrobrevin, beta
DUSP13 dual specificity phosphatase 13
EFR3B EFR3 homolog B (S. cerevisiae)
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ENO3 enolase 3 (beta, muscle)
EXOSC2 exosome component 2
EXPH5 exophilin 5
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FETUB fetuin B
FGFR1 fibroblast growth factor receptor 1
FHL1 four and a half LIM domains 1
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GGT1 gamma-glutamyltransferase 1
GLB1L galactosidase, beta 1-like
GPR3 G protein-coupled receptor 3
GRIP2 glutamate receptor interacting protein 2
GSK3A glycogen synthase kinase 3 alpha
HFE hemochromatosis
HLA-DOA major histocompatibility complex, class II, DO alpha
IKZF1 IKAROS family zinc finger 1 (Ikaros)
ING4 inhibitor of growth family, member 4
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IRF8 interferon regulatory factor 8
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPK1 inositol-tetrakisphosphate 1-kinase
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAT2 linker for activation of T cells family, member 2
LTBP4 latent transforming growth factor beta binding protein 4
MALL mal, T-cell differentiation protein-like
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MATK megakaryocyte-associated tyrosine kinase
MEP1B meprin A, beta
MFSD6 major facilitator superfamily domain containing 6
MMP26 matrix metallopeptidase 26
MTMR7 myotubularin related protein 7
NTM neurotrimin
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUP188 nucleoporin 188kDa
NXF2 nuclear RNA export factor 2
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PCDH12 protocadherin 12
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLEK pleckstrin
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PPP1R37 protein phosphatase 1, regulatory subunit 37
PTCRA pre T-cell antigen receptor alpha
PTRF polymerase I and transcript release factor
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBMS2 RNA binding motif, single stranded interacting protein 2
RHEB Ras homolog enriched in brain
RIN3 Ras and Rab interactor 3
RNF126P1 ring finger protein 126 pseudogene 1
SIPA1L3 signal-induced proliferation-associated 1 like 3
SIX3 SIX homeobox 3
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPTBN5 spectrin, beta, non-erythrocytic 5
SYNC syncoilin, intermediate filament protein
TBX5 T-box 5
TCP10L t-complex 10-like
THAP9 THAP domain containing 9
TJAP1 tight junction associated protein 1 (peripheral)
TMLHE trimethyllysine hydroxylase, epsilon
USP9Y ubiquitin specific peptidase 9, Y-linked
XYLB xylulokinase homolog (H. influenzae)
ZNF197 zinc finger protein 197
ZNF44 zinc finger protein 44

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABHD3 abhydrolase domain containing 3
AFAP1 actin filament associated protein 1
AGMAT agmatine ureohydrolase (agmatinase)
ARC activity-regulated cytoskeleton-associated protein
ATG9A autophagy related 9A
ATXN2L ataxin 2-like
BTF3P12 basic transcription factor 3 pseudogene 12
C10ORF88 chromosome 10 open reading frame 88
C14ORF79 chromosome 14 open reading frame 79
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CALCOCO1 calcium binding and coiled-coil domain 1
CAPN15 calpain 15
CBX4 chromobox homolog 4
CCRL2 chemokine (C-C motif) receptor-like 2
CENPO centromere protein O
CIDEC cell death-inducing DFFA-like effector c
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
DNAAF2 dynein, axonemal, assembly factor 2
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EFNA3 ephrin-A3
EHBP1L1 EH domain binding protein 1-like 1
EXO5 exonuclease 5
FAM110B family with sequence similarity 110, member B
FAM120C family with sequence similarity 120C
FAM131A family with sequence similarity 131, member A
FAM189A2 family with sequence similarity 189, member A2
GALK1 galactokinase 1
GID4 GID complex subunit 4
HIST1H2AI histone cluster 1, H2ai
HOXA4 homeobox A4
HOXC8 homeobox C8
HSPA1L heat shock 70kDa protein 1-like
IDI2-AS1 IDI2 antisense RNA 1
INPP5J inositol polyphosphate-5-phosphatase J
KLHL25 kelch-like family member 25
LARP6 La ribonucleoprotein domain family, member 6
LGALS4 lectin, galactoside-binding, soluble, 4
LOC390998 ribosomal protein L10 pseudogene
LY6G6C lymphocyte antigen 6 complex, locus G6C
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MDM4 MDM4, p53 regulator
NEUROD4 neuronal differentiation 4
NME5 NME/NM23 family member 5
NT5E 5'-nucleotidase, ecto (CD73)
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PAIP2B poly(A) binding protein interacting protein 2B
PCDHB8 protocadherin beta 8
PCDHGB5 protocadherin gamma subfamily B, 5
PGR progesterone receptor
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PTDSS2 phosphatidylserine synthase 2
QPCT glutaminyl-peptide cyclotransferase
RNF2 ring finger protein 2
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPA4 replication protein A4, 30kDa
SAMD9 sterile alpha motif domain containing 9
SCAMP4 secretory carrier membrane protein 4
SCGB2A2 secretoglobin, family 2A, member 2
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC41A3 solute carrier family 41, member 3
SLC44A1 solute carrier family 44 (choline transporter), member 1
SOX12 SRY (sex determining region Y)-box 12
SPIDR scaffolding protein involved in DNA repair
SPINK5 serine peptidase inhibitor, Kazal type 5
STEAP1 six transmembrane epithelial antigen of the prostate 1
STEAP4 STEAP family member 4
STX1A syntaxin 1A (brain)
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYCP2 synaptonemal complex protein 2
TAGLN transgelin
TBX19 T-box 19
TCTN2 tectonic family member 2
TFF2 trefoil factor 2
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMOD1 tropomodulin 1
TNS2 tensin 2
TRIM21 tripartite motif containing 21
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TTBK2 tau tubulin kinase 2
UBTD1 ubiquitin domain containing 1
UBXN6 UBX domain protein 6
USB1 U6 snRNA biogenesis 1
WDR62 WD repeat domain 62
ZBTB10 zinc finger and BTB domain containing 10
ZBTB44 zinc finger and BTB domain containing 44
ZNF10 zinc finger protein 10
ZNF16 zinc finger protein 16
ZNF37BP zinc finger protein 37B, pseudogene
ZNF423 zinc finger protein 423
ZNF701 zinc finger protein 701
ZNF74 zinc finger protein 74
ZNF747 zinc finger protein 747
ZNF816 zinc finger protein 816