primaquine-1343 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the primaquine-1343 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABHD5 abhydrolase domain containing 5
APP amyloid beta (A4) precursor protein
ARMC7 armadillo repeat containing 7
ATF3 activating transcription factor 3
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BCL6 B-cell CLL/lymphoma 6
BIRC3 baculoviral IAP repeat containing 3
BNC2 basonuclin 2
C17ORF53 chromosome 17 open reading frame 53
CALR calreticulin
CCL20 chemokine (C-C motif) ligand 20
CD69 CD69 molecule
CD83 CD83 molecule
CIDEC cell death-inducing DFFA-like effector c
CRELD2 cysteine-rich with EGF-like domains 2
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL8 chemokine (C-X-C motif) ligand 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DDIT3 DNA-damage-inducible transcript 3
DUSP1 dual specificity phosphatase 1
DUSP2 dual specificity phosphatase 2
DUSP5 dual specificity phosphatase 5
DUSP8 dual specificity phosphatase 8
EGR1 early growth response 1
EGR2 early growth response 2
EIF5 eukaryotic translation initiation factor 5
EPHA4 EPH receptor A4
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
F12 coagulation factor XII (Hageman factor)
FAM53C family with sequence similarity 53, member C
FCAR Fc fragment of IgA receptor
FKBP4 FK506 binding protein 4, 59kDa
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
HBEGF heparin-binding EGF-like growth factor
HCAR3 hydroxycarboxylic acid receptor 3
HIPK2 homeodomain interacting protein kinase 2
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HRH1 histamine receptor H1
IL1B interleukin 1, beta
IL24 interleukin 24
IRGQ immunity-related GTPase family, Q
JUN jun proto-oncogene
JUNB jun B proto-oncogene
KDM5A lysine (K)-specific demethylase 5A
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP4 microtubule-associated protein 4
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MEGF8 multiple EGF-like-domains 8
NFIC nuclear factor I/C (CCAAT-binding transcription factor)
NFIL3 nuclear factor, interleukin 3 regulated
NMT1 N-myristoyltransferase 1
NQO1 NAD(P)H dehydrogenase, quinone 1
NSUN6 NOP2/Sun domain family, member 6
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PBX2 pre-B-cell leukemia homeobox 2
PDLIM7 PDZ and LIM domain 7 (enigma)
PEX6 peroxisomal biogenesis factor 6
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLIN2 perilipin 2
PNOC prepronociceptin
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PVR poliovirus receptor
PYGB phosphorylase, glycogen; brain
QTRT1 queuine tRNA-ribosyltransferase 1
RCAN1 regulator of calcineurin 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHOB ras homolog family member B
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RND1 Rho family GTPase 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SDF2L1 stromal cell-derived factor 2-like 1
SEC24A SEC24 family member A
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SQSTM1 sequestosome 1
SRR serine racemase
TBL1X transducin (beta)-like 1X-linked
TESK1 testis-specific kinase 1
TFR2 transferrin receptor 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TOB2 transducer of ERBB2, 2
TRAF3 TNF receptor-associated factor 3
TRAF4 TNF receptor-associated factor 4
UGCG UDP-glucose ceramide glucosyltransferase
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WNT6 wingless-type MMTV integration site family, member 6
ZBTB10 zinc finger and BTB domain containing 10
ZBTB43 zinc finger and BTB domain containing 43
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACO1 aconitase 1, soluble
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADORA3 adenosine A3 receptor
ALPK1 alpha-kinase 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANP32A-IT1 ANP32A intronic transcript 1
ANXA2P2 annexin A2 pseudogene 2
B3GNT1
BST1 bone marrow stromal cell antigen 1
C1QTNF3 C1q and tumor necrosis factor related protein 3
CA5BP1 carbonic anhydrase VB pseudogene 1
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3
CARD9 caspase recruitment domain family, member 9
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBX7 chromobox homolog 7
CCDC69 coiled-coil domain containing 69
CCNB1 cyclin B1
CD300C CD300c molecule
CDADC1 cytidine and dCMP deaminase domain containing 1
CDK3 cyclin-dependent kinase 3
CDKN3 cyclin-dependent kinase inhibitor 3
CLSPN claspin
CORO2A coronin, actin binding protein, 2A
DBF4B DBF4 zinc finger B
DCPS decapping enzyme, scavenger
DEPDC1 DEP domain containing 1
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ELP6 elongator acetyltransferase complex subunit 6
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EXOC5 exocyst complex component 5
FBXO46 F-box protein 46
FHIT fragile histidine triad
FLCN folliculin
GINS4 GINS complex subunit 4 (Sld5 homolog)
GMCL1 germ cell-less, spermatogenesis associated 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GRAMD1B GRAM domain containing 1B
GRWD1 glutamate-rich WD repeat containing 1
GUSBP3 glucuronidase, beta pseudogene 3
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIST1H2BK histone cluster 1, H2bk
HP1BP3 heterochromatin protein 1, binding protein 3
IREB2 iron-responsive element binding protein 2
KDM5C lysine (K)-specific demethylase 5C
LIMD2 LIM domain containing 2
LRRC37A3 leucine rich repeat containing 37, member A3
MXD3 MAX dimerization protein 3
MYL5 myosin, light chain 5, regulatory
NMRK1 nicotinamide riboside kinase 1
NOL12 nucleolar protein 12
NPFFR1 neuropeptide FF receptor 1
NPIPB3 nuclear pore complex interacting protein family, member B3
NR1H3 nuclear receptor subfamily 1, group H, member 3
PARPBP PARP1 binding protein
PLS1 plastin 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PSRC1 proline/serine-rich coiled-coil 1
RAB23 RAB23, member RAS oncogene family
RNF122 ring finger protein 122
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF144A ring finger protein 144A
RNFT1 ring finger protein, transmembrane 1
RPL39L ribosomal protein L39-like
SALL2 spalt-like transcription factor 2
SAMD9 sterile alpha motif domain containing 9
SCD5 stearoyl-CoA desaturase 5
SERPINB10 serpin peptidase inhibitor, clade B (ovalbumin), member 10
SIDT1 SID1 transmembrane family, member 1
SLA Src-like-adaptor
SLC12A9 solute carrier family 12, member 9
SLC25A40 solute carrier family 25, member 40
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SMA4 glucuronidase, beta pseudogene
SNX10 sorting nexin 10
SPA17 sperm autoantigenic protein 17
STAG3 stromal antigen 3
STAR steroidogenic acute regulatory protein
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAOK1 TAO kinase 1
TDRD7 tudor domain containing 7
THRAP3 thyroid hormone receptor associated protein 3
TMEM187 transmembrane protein 187
TMEM53 transmembrane protein 53
TRIM25 tripartite motif containing 25
TUBA3C tubulin, alpha 3c
TUBGCP5 tubulin, gamma complex associated protein 5
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UPB1 ureidopropionase, beta
VANGL1 VANGL planar cell polarity protein 1
YEATS4 YEATS domain containing 4
ZBED8 zinc finger, BED-type containing 8
ZC4H2 zinc finger, C4H2 domain containing
ZNF552 zinc finger protein 552
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652
ZNF665 zinc finger protein 665
ZNF747 zinc finger protein 747