| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the primaquine-3279 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AEN | apoptosis enhancing nuclease |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AMPD3 | adenosine monophosphate deaminase 3 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ASPH | aspartate beta-hydroxylase |
| ATF3 | activating transcription factor 3 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BIN1 | bridging integrator 1 |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CCDC64 | coiled-coil domain containing 64 |
| CCDC85C | coiled-coil domain containing 85C |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CTGF | connective tissue growth factor |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DMWD | dystrophia myotonica, WD repeat containing |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DNMBP | dynamin binding protein |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP10 | dual specificity phosphatase 10 |
| EDN1 | endothelin 1 |
| EGR1 | early growth response 1 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| FAS | Fas cell surface death receptor |
| FH | fumarate hydratase |
| FHL1 | four and a half LIM domains 1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLT4 | fms-related tyrosine kinase 4 |
| FOSL1 | FOS-like antigen 1 |
| FOSL2 | FOS-like antigen 2 |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| H1FX | H1 histone family, member X |
| HBEGF | heparin-binding EGF-like growth factor |
| HIST1H4C | histone cluster 1, H4c |
| HMOX1 | heme oxygenase 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IL5RA | interleukin 5 receptor, alpha |
| INO80D | INO80 complex subunit D |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| IRS2 | insulin receptor substrate 2 |
| JUN | jun proto-oncogene |
| KAT6A | K(lysine) acetyltransferase 6A |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLF6 | Kruppel-like factor 6 |
| LIF | leukemia inhibitory factor |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LRRC15 | leucine rich repeat containing 15 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MTA1 | metastasis associated 1 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle |
| NACA | nascent polypeptide-associated complex alpha subunit |
| NCF4 | neutrophil cytosolic factor 4, 40kDa |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLAU | plasminogen activator, urokinase |
| PLK3 | polo-like kinase 3 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 |
| RGS20 | regulator of G-protein signaling 20 |
| RND1 | Rho family GTPase 1 |
| RPL5 | ribosomal protein L5 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SIRT6 | sirtuin 6 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMAD3 | SMAD family member 3 |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TCP10 | t-complex 10 |
| TGFB2 | transforming growth factor, beta 2 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TXNRD1 | thioredoxin reductase 1 |
| UPP1 | uridine phosphorylase 1 |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| VLDLR | very low density lipoprotein receptor |
| ZYX | zyxin |
| Symbol | Name |
|---|---|
| ADAM15 | ADAM metallopeptidase domain 15 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANKRD36B | ankyrin repeat domain 36B |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ASB8 | ankyrin repeat and SOCS box containing 8 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| ATP11B | ATPase, class VI, type 11B |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCORL1 | BCL6 corepressor-like 1 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| BMP4 | bone morphogenetic protein 4 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C2ORF68 | chromosome 2 open reading frame 68 |
| CASD1 | CAS1 domain containing 1 |
| CCDC15 | coiled-coil domain containing 15 |
| CCDC6 | coiled-coil domain containing 6 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CENPJ | centromere protein J |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| DCAF16 | DDB1 and CUL4 associated factor 16 |
| DENND4C | DENN/MADD domain containing 4C |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EGR3 | early growth response 3 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| EML4 | echinoderm microtubule associated protein like 4 |
| EXOC5 | exocyst complex component 5 |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FZD3 | frizzled class receptor 3 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GHR | growth hormone receptor |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GPR19 | G protein-coupled receptor 19 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GTF2I | general transcription factor IIi |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HELLS | helicase, lymphoid-specific |
| HIRA | histone cell cycle regulator |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H2BG | histone cluster 1, H2bg |
| HIST1H4F | histone cluster 1, H4f |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IL4R | interleukin 4 receptor |
| INCENP | inner centromere protein antigens 135/155kDa |
| IPP | intracisternal A particle-promoted polypeptide |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KDM5C | lysine (K)-specific demethylase 5C |
| LIN37 | lin-37 DREAM MuvB core complex component |
| LOC100287590 | uncharacterized LOC100287590 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LOC730101 | uncharacterized LOC730101 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MED18 | mediator complex subunit 18 |
| METTL16 | methyltransferase like 16 |
| MGC12488 | |
| MPHOSPH8 | M-phase phosphoprotein 8 |
| MTMR11 | myotubularin related protein 11 |
| MTRF1 | mitochondrial translational release factor 1 |
| NAIP | NLR family, apoptosis inhibitory protein |
| NPY1R | neuropeptide Y receptor Y1 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| RGS17 | regulator of G-protein signaling 17 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNFT1 | ring finger protein, transmembrane 1 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RWDD2A | RWD domain containing 2A |
| SCAI | suppressor of cancer cell invasion |
| SERTAD3 | SERTA domain containing 3 |
| SIX1 | SIX homeobox 1 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TDRD1 | tudor domain containing 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TIPRL | TOR signaling pathway regulator |
| TPCN1 | two pore segment channel 1 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| VASH2 | vasohibin 2 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZDHHC13 | zinc finger, DHHC-type containing 13 |
| ZNF160 | zinc finger protein 160 |
| ZNF430 | zinc finger protein 430 |
| ZNF587 | zinc finger protein 587 |
| ZNF652 | zinc finger protein 652 |
| ZNF721 | zinc finger protein 721 |