| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the primaquine-4263 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABAT | 4-aminobutyrate aminotransferase |
| ABCC9 | ATP-binding cassette, sub-family C (CFTR/MRP), member 9 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACRV1 | acrosomal vesicle protein 1 |
| AGXT | alanine-glyoxylate aminotransferase |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| APOE | apolipoprotein E |
| ART4 | ADP-ribosyltransferase 4 (Dombrock blood group) |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BTG2 | BTG family, member 2 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CAMTA1 | calmodulin binding transcription activator 1 |
| CASS4 | Cas scaffolding protein family member 4 |
| CCL23 | chemokine (C-C motif) ligand 23 |
| CDHR5 | cadherin-related family member 5 |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) |
| CHGA | chromogranin A |
| CKM | creatine kinase, muscle |
| CLCA2 | chloride channel accessory 2 |
| CSDC2 | cold shock domain containing C2, RNA binding |
| CYP2U1 | cytochrome P450, family 2, subfamily U, polypeptide 1 |
| DEFB4A | defensin, beta 4A |
| DRP2 | dystrophin related protein 2 |
| DUSP1 | dual specificity phosphatase 1 |
| EDA | ectodysplasin A |
| EDN3 | endothelin 3 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EMILIN1 | elastin microfibril interfacer 1 |
| EPHA7 | EPH receptor A7 |
| ESR1 | estrogen receptor 1 |
| FGA | fibrinogen alpha chain |
| FGF6 | fibroblast growth factor 6 |
| FOXP3 | forkhead box P3 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| HOXD13 | homeobox D13 |
| HRG | histidine-rich glycoprotein |
| HTR5A | 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled |
| IFNA6 | interferon, alpha 6 |
| IGFALS | insulin-like growth factor binding protein, acid labile subunit |
| IGSF1 | immunoglobulin superfamily, member 1 |
| IL1RN | interleukin 1 receptor antagonist |
| IL21 | interleukin 21 |
| INS | insulin |
| ITGB7 | integrin, beta 7 |
| KCNC1 | potassium channel, voltage gated Shaw related subfamily C, member 1 |
| KCNQ1 | potassium channel, voltage gated KQT-like subfamily Q, member 1 |
| KLF6 | Kruppel-like factor 6 |
| KRT16 | keratin 16, type I |
| KRT17 | keratin 17, type I |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 |
| LSAMP | limbic system-associated membrane protein |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 |
| MTMR8 | myotubularin related protein 8 |
| MYCNOS | MYCN opposite strand |
| MYO1B | myosin IB |
| MYT1 | myelin transcription factor 1 |
| NECAB2 | N-terminal EF-hand calcium binding protein 2 |
| NIPAL3 | NIPA-like domain containing 3 |
| NME8 | NME/NM23 family member 8 |
| NRXN2 | neurexin 2 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| OTOF | otoferlin |
| P2RX7 | purinergic receptor P2X, ligand gated ion channel, 7 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PRB4 | proline-rich protein BstNI subfamily 4 |
| PRDM14 | PR domain containing 14 |
| PRDM9 | PR domain containing 9 |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 |
| RCE1 | Ras converting CAAX endopeptidase 1 |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RFPL1 | ret finger protein-like 1 |
| SERPINA10 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC13A4 | solute carrier family 13 (sodium/sulfate symporter), member 4 |
| SLC17A4 | solute carrier family 17, member 4 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC6A11 | solute carrier family 6 (neurotransmitter transporter), member 11 |
| SNED1 | sushi, nidogen and EGF-like domains 1 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) |
| ST8SIA5 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 |
| STK3 | serine/threonine kinase 3 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TK2 | thymidine kinase 2, mitochondrial |
| TMPRSS4 | transmembrane protease, serine 4 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TPM2 | tropomyosin 2 (beta) |
| TRIM31 | tripartite motif containing 31 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZNF814 | zinc finger protein 814 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ADCY6 | adenylate cyclase 6 |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein |
| ARHGAP11A | Rho GTPase activating protein 11A |
| ARL14 | ADP-ribosylation factor-like 14 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C22ORF29 | chromosome 22 open reading frame 29 |
| CAND2 | cullin-associated and neddylation-dissociated 2 (putative) |
| CARD8 | caspase recruitment domain family, member 8 |
| CCS | copper chaperone for superoxide dismutase |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDK3 | cyclin-dependent kinase 3 |
| CISH | cytokine inducible SH2-containing protein |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CXADR | coxsackie virus and adenovirus receptor |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DNA2 | DNA replication helicase/nuclease 2 |
| EFNA3 | ephrin-A3 |
| EPHB3 | EPH receptor B3 |
| EPM2AIP1 | EPM2A (laforin) interacting protein 1 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| FAM69A | family with sequence similarity 69, member A |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPALPP1 | GPALPP motifs containing 1 |
| GPR4 | G protein-coupled receptor 4 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GSAP | gamma-secretase activating protein |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H4E | histone cluster 1, H4e |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOXA5 | homeobox A5 |
| HSPA2 | heat shock 70kDa protein 2 |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IFI35 | interferon-induced protein 35 |
| INCENP | inner centromere protein antigens 135/155kDa |
| ISL1 | ISL LIM homeobox 1 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KIAA1462 | KIAA1462 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LPPR4 | lipid phosphate phosphatase-related protein type 4 |
| LRRC37A4P | leucine rich repeat containing 37, member A4, pseudogene |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| NDP | Norrie disease (pseudoglioma) |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PTCD2 | pentatricopeptide repeat domain 2 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RIN1 | Ras and Rab interactor 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SALL2 | spalt-like transcription factor 2 |
| SGMS1 | sphingomyelin synthase 1 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC35F6 | solute carrier family 35, member F6 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SPEG | SPEG complex locus |
| TEX40 | testis expressed 40 |
| THBS3 | thrombospondin 3 |
| TMEM168 | transmembrane protein 168 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TWISTNB | TWIST neighbor |
| TXLNG | taxilin gamma |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| ZCCHC2 | zinc finger, CCHC domain containing 2 |
| ZNF189 | zinc finger protein 189 |
| ZNF200 | zinc finger protein 200 |
| ZNF254 | zinc finger protein 254 |
| ZNF286A | zinc finger protein 286A |
| ZNF33B | zinc finger protein 33B |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF552 | zinc finger protein 552 |
| ZNF606 | zinc finger protein 606 |
| ZNF696 | zinc finger protein 696 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |