Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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192 genes differentially expressed following the primidone-3065 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
ABHD8 | abhydrolase domain containing 8 |
ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
AKR1C4 | aldo-keto reductase family 1, member C4 |
ANG | angiogenin, ribonuclease, RNase A family, 5 |
AP4S1 | adaptor-related protein complex 4, sigma 1 subunit |
ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
ATF7IP | activating transcription factor 7 interacting protein |
BCAS3 | breast carcinoma amplified sequence 3 |
C7ORF26 | chromosome 7 open reading frame 26 |
CCDC181 | coiled-coil domain containing 181 |
CCDC85B | coiled-coil domain containing 85B |
CEP170B | centrosomal protein 170B |
CLIC2 | chloride intracellular channel 2 |
CLU | clusterin |
COL10A1 | collagen, type X, alpha 1 |
COL6A1 | collagen, type VI, alpha 1 |
COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
CRABP2 | cellular retinoic acid binding protein 2 |
CSPG4 | chondroitin sulfate proteoglycan 4 |
CTNS | cystinosin, lysosomal cystine transporter |
DAPK2 | death-associated protein kinase 2 |
DIRAS3 | DIRAS family, GTP-binding RAS-like 3 |
DNMT3L | DNA (cytosine-5-)-methyltransferase 3-like |
DNPEP | aspartyl aminopeptidase |
DOCK9 | dedicator of cytokinesis 9 |
DUOX1 | dual oxidase 1 |
ECE1 | endothelin converting enzyme 1 |
EML2 | echinoderm microtubule associated protein like 2 |
ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
EXT1 | exostosin glycosyltransferase 1 |
FAM65B | family with sequence similarity 65, member B |
FBXL18 | F-box and leucine-rich repeat protein 18 |
GK3P | glycerol kinase 3 pseudogene |
GNPTAB | N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits |
GPC1 | glypican 1 |
GPM6B | glycoprotein M6B |
GPR20 | G protein-coupled receptor 20 |
GPR22 | G protein-coupled receptor 22 |
H2AFJ | H2A histone family, member J |
HTR1D | 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled |
IL1R1 | interleukin 1 receptor, type I |
IL1R2 | interleukin 1 receptor, type II |
IL6ST | interleukin 6 signal transducer |
KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
KLC2 | kinesin light chain 2 |
KYNU | kynureninase |
LDB3 | LIM domain binding 3 |
MECOM | MDS1 and EVI1 complex locus |
MIER2 | mesoderm induction early response 1, family member 2 |
MPP5 | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) |
MSTN | myostatin |
MTCP1 | mature T-cell proliferation 1 |
MTMR7 | myotubularin related protein 7 |
MXD4 | MAX dimerization protein 4 |
MXRA5 | matrix-remodelling associated 5 |
MYL10 | myosin, light chain 10, regulatory |
NPAS1 | neuronal PAS domain protein 1 |
NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
OPRM1 | opioid receptor, mu 1 |
PAPPA2 | pappalysin 2 |
PART1 | prostate androgen-regulated transcript 1 (non-protein coding) |
PAX8 | paired box 8 |
PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
PDLIM3 | PDZ and LIM domain 3 |
PDLIM4 | PDZ and LIM domain 4 |
PIGR | polymeric immunoglobulin receptor |
PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
PKP1 | plakophilin 1 |
PLN | phospholamban |
PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
POFUT2 | protein O-fucosyltransferase 2 |
PORCN | porcupine homolog (Drosophila) |
POU6F1 | POU class 6 homeobox 1 |
PPP1R37 | protein phosphatase 1, regulatory subunit 37 |
PQLC2 | PQ loop repeat containing 2 |
PTGIS | prostaglandin I2 (prostacyclin) synthase |
PTHLH | parathyroid hormone-like hormone |
RARA | retinoic acid receptor, alpha |
RTEL1 | regulator of telomere elongation helicase 1 |
RWDD3 | RWD domain containing 3 |
SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
SLC26A1 | solute carrier family 26 (anion exchanger), member 1 |
SLC35D2 | solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 |
SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
SLC7A10 | solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 |
SNX13 | sorting nexin 13 |
SPTBN5 | spectrin, beta, non-erythrocytic 5 |
SUPT20H | suppressor of Ty 20 homolog (S. cerevisiae) |
TMCC1 | transmembrane and coiled-coil domain family 1 |
TMPRSS6 | transmembrane protease, serine 6 |
TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 |
ZER1 | zyg-11 related, cell cycle regulator |
ZNF528 | zinc finger protein 528 |
Symbol | Name |
---|---|
ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
ACBD4 | acyl-CoA binding domain containing 4 |
AMDHD2 | amidohydrolase domain containing 2 |
AUTS2 | autism susceptibility candidate 2 |
C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
C8ORF4 | chromosome 8 open reading frame 4 |
CACNB4 | calcium channel, voltage-dependent, beta 4 subunit |
CCNK | cyclin K |
CD34 | CD34 molecule |
CENPO | centromere protein O |
CFAP45 | cilia and flagella associated protein 45 |
CFP | complement factor properdin |
CISH | cytokine inducible SH2-containing protein |
CKM | creatine kinase, muscle |
COPG2IT1 | COPG2 imprinted transcript 1 (non-protein coding) |
CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
DGKG | diacylglycerol kinase, gamma 90kDa |
EMILIN1 | elastin microfibril interfacer 1 |
EMILIN2 | elastin microfibril interfacer 2 |
F2RL2 | coagulation factor II (thrombin) receptor-like 2 |
FAAH | fatty acid amide hydrolase |
FAM131A | family with sequence similarity 131, member A |
FER | fer (fps/fes related) tyrosine kinase |
FGF22 | fibroblast growth factor 22 |
FOXO4 | forkhead box O4 |
FRMD1 | FERM domain containing 1 |
FRS3 | fibroblast growth factor receptor substrate 3 |
GATA4 | GATA binding protein 4 |
GMPR | guanosine monophosphate reductase |
GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
GUCA2A | guanylate cyclase activator 2A (guanylin) |
HIST1H1B | histone cluster 1, H1b |
HIST1H2BC | histone cluster 1, H2bc |
HTR6 | 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled |
IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
INCENP | inner centromere protein antigens 135/155kDa |
INO80D | INO80 complex subunit D |
KRT8P12 | keratin 8 pseudogene 12 |
KRT9 | keratin 9, type I |
LIG4 | ligase IV, DNA, ATP-dependent |
LIMS2 | LIM and senescent cell antigen-like domains 2 |
LRRC6 | leucine rich repeat containing 6 |
LY6G6C | lymphocyte antigen 6 complex, locus G6C |
MNX1 | motor neuron and pancreas homeobox 1 |
MYBPH | myosin binding protein H |
MYLK | myosin light chain kinase |
MYO3A | myosin IIIA |
NDE1 | nudE neurodevelopment protein 1 |
NEFM | neurofilament, medium polypeptide |
NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
NNAT | neuronatin |
NOL10 | nucleolar protein 10 |
NXF2 | nuclear RNA export factor 2 |
NXPH4 | neurexophilin 4 |
OMG | oligodendrocyte myelin glycoprotein |
PGLYRP4 | peptidoglycan recognition protein 4 |
POM121L2 | POM121 transmembrane nucleoporin-like 2 |
PSG4 | pregnancy specific beta-1-glycoprotein 4 |
PTPRK | protein tyrosine phosphatase, receptor type, K |
RAB11B | RAB11B, member RAS oncogene family |
RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
RAP1GAP2 | RAP1 GTPase activating protein 2 |
RIN2 | Ras and Rab interactor 2 |
RNF122 | ring finger protein 122 |
RNF126P1 | ring finger protein 126 pseudogene 1 |
RPL34 | ribosomal protein L34 |
SAA3P | serum amyloid A3 pseudogene |
SCG5 | secretogranin V |
SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A |
SFTPA2 | surfactant protein A2 |
SIT1 | signaling threshold regulating transmembrane adaptor 1 |
SIX3 | SIX homeobox 3 |
SLC12A8 | solute carrier family 12, member 8 |
SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
SPHK1 | sphingosine kinase 1 |
SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
STRN | striatin, calmodulin binding protein |
TAAR3 | trace amine associated receptor 3 (gene/pseudogene) |
TAGLN3 | transgelin 3 |
TFF2 | trefoil factor 2 |
TMEM212 | transmembrane protein 212 |
TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 |
TPTE | transmembrane phosphatase with tensin homology |
TRAF3IP1 | TNF receptor-associated factor 3 interacting protein 1 |
UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
VASH1 | vasohibin 1 |
VPS9D1 | VPS9 domain containing 1 |
WDR62 | WD repeat domain 62 |
ZNF10 | zinc finger protein 10 |
ZNF219 | zinc finger protein 219 |
ZNF385D | zinc finger protein 385D |
ZNF484 | zinc finger protein 484 |