primidone-3065 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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192 genes differentially expressed following the primidone-3065 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD8 abhydrolase domain containing 8
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
AKR1C4 aldo-keto reductase family 1, member C4
ANG angiogenin, ribonuclease, RNase A family, 5
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ATF7IP activating transcription factor 7 interacting protein
BCAS3 breast carcinoma amplified sequence 3
C7ORF26 chromosome 7 open reading frame 26
CCDC181 coiled-coil domain containing 181
CCDC85B coiled-coil domain containing 85B
CEP170B centrosomal protein 170B
CLIC2 chloride intracellular channel 2
CLU clusterin
COL10A1 collagen, type X, alpha 1
COL6A1 collagen, type VI, alpha 1
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
CRABP2 cellular retinoic acid binding protein 2
CSPG4 chondroitin sulfate proteoglycan 4
CTNS cystinosin, lysosomal cystine transporter
DAPK2 death-associated protein kinase 2
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like
DNPEP aspartyl aminopeptidase
DOCK9 dedicator of cytokinesis 9
DUOX1 dual oxidase 1
ECE1 endothelin converting enzyme 1
EML2 echinoderm microtubule associated protein like 2
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EXT1 exostosin glycosyltransferase 1
FAM65B family with sequence similarity 65, member B
FBXL18 F-box and leucine-rich repeat protein 18
GK3P glycerol kinase 3 pseudogene
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPC1 glypican 1
GPM6B glycoprotein M6B
GPR20 G protein-coupled receptor 20
GPR22 G protein-coupled receptor 22
H2AFJ H2A histone family, member J
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
IL1R1 interleukin 1 receptor, type I
IL1R2 interleukin 1 receptor, type II
IL6ST interleukin 6 signal transducer
KCNK12 potassium channel, two pore domain subfamily K, member 12
KLC2 kinesin light chain 2
KYNU kynureninase
LDB3 LIM domain binding 3
MECOM MDS1 and EVI1 complex locus
MIER2 mesoderm induction early response 1, family member 2
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MSTN myostatin
MTCP1 mature T-cell proliferation 1
MTMR7 myotubularin related protein 7
MXD4 MAX dimerization protein 4
MXRA5 matrix-remodelling associated 5
MYL10 myosin, light chain 10, regulatory
NPAS1 neuronal PAS domain protein 1
NR2E3 nuclear receptor subfamily 2, group E, member 3
OPRM1 opioid receptor, mu 1
PAPPA2 pappalysin 2
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PAX8 paired box 8
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDLIM3 PDZ and LIM domain 3
PDLIM4 PDZ and LIM domain 4
PIGR polymeric immunoglobulin receptor
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PKP1 plakophilin 1
PLN phospholamban
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POFUT2 protein O-fucosyltransferase 2
PORCN porcupine homolog (Drosophila)
POU6F1 POU class 6 homeobox 1
PPP1R37 protein phosphatase 1, regulatory subunit 37
PQLC2 PQ loop repeat containing 2
PTGIS prostaglandin I2 (prostacyclin) synthase
PTHLH parathyroid hormone-like hormone
RARA retinoic acid receptor, alpha
RTEL1 regulator of telomere elongation helicase 1
RWDD3 RWD domain containing 3
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC26A1 solute carrier family 26 (anion exchanger), member 1
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A10 solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10
SNX13 sorting nexin 13
SPTBN5 spectrin, beta, non-erythrocytic 5
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
TMCC1 transmembrane and coiled-coil domain family 1
TMPRSS6 transmembrane protease, serine 6
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
ZER1 zyg-11 related, cell cycle regulator
ZNF528 zinc finger protein 528

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACBD4 acyl-CoA binding domain containing 4
AMDHD2 amidohydrolase domain containing 2
AUTS2 autism susceptibility candidate 2
C1QTNF1 C1q and tumor necrosis factor related protein 1
C8ORF4 chromosome 8 open reading frame 4
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CCNK cyclin K
CD34 CD34 molecule
CENPO centromere protein O
CFAP45 cilia and flagella associated protein 45
CFP complement factor properdin
CISH cytokine inducible SH2-containing protein
CKM creatine kinase, muscle
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DGKG diacylglycerol kinase, gamma 90kDa
EMILIN1 elastin microfibril interfacer 1
EMILIN2 elastin microfibril interfacer 2
F2RL2 coagulation factor II (thrombin) receptor-like 2
FAAH fatty acid amide hydrolase
FAM131A family with sequence similarity 131, member A
FER fer (fps/fes related) tyrosine kinase
FGF22 fibroblast growth factor 22
FOXO4 forkhead box O4
FRMD1 FERM domain containing 1
FRS3 fibroblast growth factor receptor substrate 3
GATA4 GATA binding protein 4
GMPR guanosine monophosphate reductase
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUCA2A guanylate cyclase activator 2A (guanylin)
HIST1H1B histone cluster 1, H1b
HIST1H2BC histone cluster 1, H2bc
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
INCENP inner centromere protein antigens 135/155kDa
INO80D INO80 complex subunit D
KRT8P12 keratin 8 pseudogene 12
KRT9 keratin 9, type I
LIG4 ligase IV, DNA, ATP-dependent
LIMS2 LIM and senescent cell antigen-like domains 2
LRRC6 leucine rich repeat containing 6
LY6G6C lymphocyte antigen 6 complex, locus G6C
MNX1 motor neuron and pancreas homeobox 1
MYBPH myosin binding protein H
MYLK myosin light chain kinase
MYO3A myosin IIIA
NDE1 nudE neurodevelopment protein 1
NEFM neurofilament, medium polypeptide
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NNAT neuronatin
NOL10 nucleolar protein 10
NXF2 nuclear RNA export factor 2
NXPH4 neurexophilin 4
OMG oligodendrocyte myelin glycoprotein
PGLYRP4 peptidoglycan recognition protein 4
POM121L2 POM121 transmembrane nucleoporin-like 2
PSG4 pregnancy specific beta-1-glycoprotein 4
PTPRK protein tyrosine phosphatase, receptor type, K
RAB11B RAB11B, member RAS oncogene family
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RAP1GAP2 RAP1 GTPase activating protein 2
RIN2 Ras and Rab interactor 2
RNF122 ring finger protein 122
RNF126P1 ring finger protein 126 pseudogene 1
RPL34 ribosomal protein L34
SAA3P serum amyloid A3 pseudogene
SCG5 secretogranin V
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SFTPA2 surfactant protein A2
SIT1 signaling threshold regulating transmembrane adaptor 1
SIX3 SIX homeobox 3
SLC12A8 solute carrier family 12, member 8
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPHK1 sphingosine kinase 1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STRN striatin, calmodulin binding protein
TAAR3 trace amine associated receptor 3 (gene/pseudogene)
TAGLN3 transgelin 3
TFF2 trefoil factor 2
TMEM212 transmembrane protein 212
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TPTE transmembrane phosphatase with tensin homology
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
VASH1 vasohibin 1
VPS9D1 VPS9 domain containing 1
WDR62 WD repeat domain 62
ZNF10 zinc finger protein 10
ZNF219 zinc finger protein 219
ZNF385D zinc finger protein 385D
ZNF484 zinc finger protein 484