| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the primidone-6723 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| A2M | alpha-2-macroglobulin |
| ADCY2 | adenylate cyclase 2 (brain) |
| ADGRF5 | adhesion G protein-coupled receptor F5 |
| ANKRD12 | ankyrin repeat domain 12 |
| ARG2 | arginase 2 |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| B9D1 | B9 protein domain 1 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C4BPA | complement component 4 binding protein, alpha |
| CD58 | CD58 molecule |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDC14B | cell division cycle 14B |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEND1 | cell cycle exit and neuronal differentiation 1 |
| CFP | complement factor properdin |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CISH | cytokine inducible SH2-containing protein |
| COBL | cordon-bleu WH2 repeat protein |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CTSS | cathepsin S |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
| EFS | embryonal Fyn-associated substrate |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 |
| EPS8L1 | EPS8-like 1 |
| EZR | ezrin |
| FAM131B | family with sequence similarity 131, member B |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GATA4 | GATA binding protein 4 |
| GPATCH4 | G patch domain containing 4 |
| GPR21 | G protein-coupled receptor 21 |
| GUK1 | guanylate kinase 1 |
| HIST1H4F | histone cluster 1, H4f |
| IER3IP1 | immediate early response 3 interacting protein 1 |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| ITGB5 | integrin, beta 5 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KIAA1467 | KIAA1467 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KRT7 | keratin 7, type II |
| LAG3 | lymphocyte-activation gene 3 |
| LDLR | low density lipoprotein receptor |
| LILRA5 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MED25 | mediator complex subunit 25 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MST1 | macrophage stimulating 1 |
| MYBPC3 | myosin binding protein C, cardiac |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NNAT | neuronatin |
| NOVA2 | neuro-oncological ventral antigen 2 |
| NPRL2 | nitrogen permease regulator-like 2 (S. cerevisiae) |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 |
| OGFR | opioid growth factor receptor |
| PADI1 | peptidyl arginine deiminase, type I |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PDCD2 | programmed cell death 2 |
| PDLIM3 | PDZ and LIM domain 3 |
| PGK1 | phosphoglycerate kinase 1 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PSORS1C1 | psoriasis susceptibility 1 candidate 1 |
| RAB2A | RAB2A, member RAS oncogene family |
| RHEB | Ras homolog enriched in brain |
| RPGRIP1L | RPGRIP1-like |
| RPL14 | ribosomal protein L14 |
| RPLP2 | ribosomal protein, large, P2 |
| RPS11 | ribosomal protein S11 |
| SAP30 | Sin3A-associated protein, 30kDa |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 |
| STK17A | serine/threonine kinase 17a |
| TAL1 | T-cell acute lymphocytic leukemia 1 |
| TBXA2R | thromboxane A2 receptor |
| TGFB2 | transforming growth factor, beta 2 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TYMS | thymidylate synthetase |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| VWA5A | von Willebrand factor A domain containing 5A |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF268 | zinc finger protein 268 |
| ZNF573 | zinc finger protein 573 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| AES | amino-terminal enhancer of split |
| AMDHD2 | amidohydrolase domain containing 2 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ASCC2 | activating signal cointegrator 1 complex subunit 2 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BRMS1 | breast cancer metastasis suppressor 1 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CBX8 | chromobox homolog 8 |
| CEP85 | centrosomal protein 85kDa |
| CHM | choroideremia (Rab escort protein 1) |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CLEC2B | C-type lectin domain family 2, member B |
| CNN2 | calponin 2 |
| CORO1A | coronin, actin binding protein, 1A |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CTSD | cathepsin D |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| DEAF1 | DEAF1 transcription factor |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DMTN | dematin actin binding protein |
| DNAJC17 | DnaJ (Hsp40) homolog, subfamily C, member 17 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| EFNB1 | ephrin-B1 |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| EXOC5 | exocyst complex component 5 |
| FKBP5 | FK506 binding protein 5 |
| FLT4 | fms-related tyrosine kinase 4 |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| H1F0 | H1 histone family, member 0 |
| HDAC7 | histone deacetylase 7 |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H3B | histone cluster 1, H3b |
| HOMER2 | homer scaffolding protein 2 |
| HSPA1L | heat shock 70kDa protein 1-like |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KLC2 | kinesin light chain 2 |
| KLF13 | Kruppel-like factor 13 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LRRC61 | leucine rich repeat containing 61 |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MVP | major vault protein |
| MXRA8 | matrix-remodelling associated 8 |
| MYH15 | myosin, heavy chain 15 |
| MYL5 | myosin, light chain 5, regulatory |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PDE8B | phosphodiesterase 8B |
| PES1 | pescadillo ribosomal biogenesis factor 1 |
| PKM | pyruvate kinase, muscle |
| PLD3 | phospholipase D family, member 3 |
| POLL | polymerase (DNA directed), lambda |
| POLM | polymerase (DNA directed), mu |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| RAPSN | receptor-associated protein of the synapse |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TCTN1 | tectonic family member 1 |
| TEAD3 | TEA domain family member 3 |
| TEX40 | testis expressed 40 |
| TMEM121 | transmembrane protein 121 |
| ULBP2 | UL16 binding protein 2 |
| VEGFB | vascular endothelial growth factor B |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF286A | zinc finger protein 286A |
| ZNF669 | zinc finger protein 669 |
