prolactin receptor|This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011] (NCBI Entrez Gene Database, 5618)
Similar Terms
Downloads & Tools
Genes
16 genes co-occuring with the biological term prlr in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.