prlr Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description prolactin receptor|This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011] (NCBI Entrez Gene Database, 5618)
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Genes

16 genes co-occuring with the biological term prlr in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
GHR growth hormone receptor
GSK3B glycogen synthase kinase 3 beta
HMGN2 high mobility group nucleosomal binding domain 2
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JAK2 Janus kinase 2
PGR progesterone receptor
PRL prolactin
PRLR prolactin receptor
SLC30A2 solute carrier family 30 (zinc transporter), member 2
STAT5A signal transducer and activator of transcription 5A
TNF tumor necrosis factor
TP53 tumor protein p53