| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the proadifen-2707 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB4 | ATP-binding cassette, sub-family B (MDR/TAP), member 4 |
| ADGRL1 | adhesion G protein-coupled receptor L1 |
| ADRA1A | adrenoceptor alpha 1A |
| ADRB3 | adrenoceptor beta 3 |
| AGXT | alanine-glyoxylate aminotransferase |
| AIM1L | absent in melanoma 1-like |
| AREG | amphiregulin |
| ARMC4 | armadillo repeat containing 4 |
| BIN1 | bridging integrator 1 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C1QL1 | complement component 1, q subcomponent-like 1 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CD80 | CD80 molecule |
| CDC14A | cell division cycle 14A |
| CEP41 | centrosomal protein 41kDa |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLEC3B | C-type lectin domain family 3, member B |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COL1A1 | collagen, type I, alpha 1 |
| CRAT | carnitine O-acetyltransferase |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 |
| CREM | cAMP responsive element modulator |
| CTGF | connective tissue growth factor |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DLX2 | distal-less homeobox 2 |
| DNAH7 | dynein, axonemal, heavy chain 7 |
| DNASE2 | deoxyribonuclease II, lysosomal |
| DNMBP | dynamin binding protein |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| ESR1 | estrogen receptor 1 |
| FBRS | fibrosin |
| FGFR1 | fibroblast growth factor receptor 1 |
| FOXA1 | forkhead box A1 |
| G0S2 | G0/G1 switch 2 |
| GATA2 | GATA binding protein 2 |
| GGA3 | golgi-associated, gamma adaptin ear containing, ARF binding protein 3 |
| GPR25 | G protein-coupled receptor 25 |
| HES1 | hes family bHLH transcription factor 1 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HOXC10 | homeobox C10 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| HTR2A | 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled |
| IGLV1-44 | immunoglobulin lambda variable 1-44 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KDR | kinase insert domain receptor |
| KIAA1654 | KIAA1654 protein |
| KIDINS220 | kinase D-interacting substrate, 220kDa |
| KLK14 | kallikrein-related peptidase 14 |
| KRT17 | keratin 17, type I |
| LRRC31 | leucine rich repeat containing 31 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MEFV | Mediterranean fever |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MUC1 | mucin 1, cell surface associated |
| MYH14 | myosin, heavy chain 14, non-muscle |
| NF1 | neurofibromin 1 |
| NPTX2 | neuronal pentraxin II |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 |
| P2RY11 | purinergic receptor P2Y, G-protein coupled, 11 |
| PCDH17 | protocadherin 17 |
| PER3 | period circadian clock 3 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PRKCE | protein kinase C, epsilon |
| PRLH | prolactin releasing hormone |
| PRR5 | proline rich 5 (renal) |
| PTCH2 | patched 2 |
| PTPRF | protein tyrosine phosphatase, receptor type, F |
| PVR | poliovirus receptor |
| QSER1 | glutamine and serine rich 1 |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RNF208 | ring finger protein 208 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
| SH2D3A | SH2 domain containing 3A |
| SIRT4 | sirtuin 4 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC6A2 | solute carrier family 6 (neurotransmitter transporter), member 2 |
| SMIM14 | small integral membrane protein 14 |
| SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SSTR4 | somatostatin receptor 4 |
| SSTR5 | somatostatin receptor 5 |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| STK17A | serine/threonine kinase 17a |
| TEX40 | testis expressed 40 |
| TGFBR3 | transforming growth factor, beta receptor III |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TSC22D2 | TSC22 domain family, member 2 |
| ULBP2 | UL16 binding protein 2 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| Symbol | Name |
|---|---|
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACOX2 | acyl-CoA oxidase 2, branched chain |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ARL15 | ADP-ribosylation factor-like 15 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| B3GNT1 | |
| BNC2 | basonuclin 2 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| CCDC85C | coiled-coil domain containing 85C |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CKB | creatine kinase, brain |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CRYGC | crystallin, gamma C |
| CTSV | cathepsin V |
| DPYS | dihydropyrimidinase |
| DSPP | dentin sialophosphoprotein |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| FAM127B | family with sequence similarity 127, member B |
| FGGY | FGGY carbohydrate kinase domain containing |
| FLT4 | fms-related tyrosine kinase 4 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| GSTT1 | glutathione S-transferase theta 1 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H3B | histone cluster 1, H3b |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HOXC8 | homeobox C8 |
| IFT140 | intraflagellar transport 140 |
| IFT81 | intraflagellar transport 81 |
| INCENP | inner centromere protein antigens 135/155kDa |
| ITGB7 | integrin, beta 7 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLHL36 | kelch-like family member 36 |
| LHFP | lipoma HMGIC fusion partner |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MAB21L1 | mab-21-like 1 (C. elegans) |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MEP1B | meprin A, beta |
| MTA2 | metastasis associated 1 family, member 2 |
| MTSS1L | metastasis suppressor 1-like |
| MXD3 | MAX dimerization protein 3 |
| NAG18 | NAG18 mRNA |
| NCALD | neurocalcin delta |
| NCS1 | neuronal calcium sensor 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NEUROD4 | neuronal differentiation 4 |
| PADI2 | peptidyl arginine deiminase, type II |
| PDE12 | phosphodiesterase 12 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIPOX | pipecolic acid oxidase |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PLA2G1B | phospholipase A2, group IB (pancreas) |
| PODXL2 | podocalyxin-like 2 |
| POLL | polymerase (DNA directed), lambda |
| POM121 | POM121 transmembrane nucleoporin |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| PRSS53 | protease, serine, 53 |
| PTCD1 | pentatricopeptide repeat domain 1 |
| RAB13 | RAB13, member RAS oncogene family |
| RCAN3 | RCAN family member 3 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SPAG4 | sperm associated antigen 4 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| STBD1 | starch binding domain 1 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TMC5 | transmembrane channel-like 5 |
| TUBB2A | tubulin, beta 2A class IIa |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 |
| UNC119 | unc-119 homolog (C. elegans) |
| VNN2 | vanin 2 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZNF493 | zinc finger protein 493 |
| ZNF528 | zinc finger protein 528 |
