| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the proadifen-3446 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACVR1B | activin A receptor, type IB |
| ALPK1 | alpha-kinase 1 |
| ATF3 | activating transcription factor 3 |
| ATP10D | ATPase, class V, type 10D |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CCNG2 | cyclin G2 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| CNN1 | calponin 1, basic, smooth muscle |
| COL7A1 | collagen, type VII, alpha 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DCAF8 | DDB1 and CUL4 associated factor 8 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DLX2 | distal-less homeobox 2 |
| DUSP10 | dual specificity phosphatase 10 |
| EDNRB | endothelin receptor type B |
| EGR1 | early growth response 1 |
| EPS8L2 | EPS8-like 2 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FPGS | folylpolyglutamate synthase |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GFI1 | growth factor independent 1 transcription repressor |
| GSN | gelsolin |
| HMOX1 | heme oxygenase 1 |
| HRK | harakiri, BCL2 interacting protein |
| ICAM1 | intercellular adhesion molecule 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| IL11 | interleukin 11 |
| INHBE | inhibin, beta E |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KCNA6 | potassium channel, voltage gated shaker related subfamily A, member 6 |
| KDM4C | lysine (K)-specific demethylase 4C |
| KDM7A | lysine (K)-specific demethylase 7A |
| KLF9 | Kruppel-like factor 9 |
| KLHL24 | kelch-like family member 24 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 |
| MAP4 | microtubule-associated protein 4 |
| MARS | methionyl-tRNA synthetase |
| MED18 | mediator complex subunit 18 |
| METTL7A | methyltransferase like 7A |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MYL10 | myosin, light chain 10, regulatory |
| NAV2 | neuron navigator 2 |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NOL12 | nucleolar protein 12 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| ONECUT1 | one cut homeobox 1 |
| PENK | proenkephalin |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| RAB40B | RAB40B, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RGS10 | regulator of G-protein signaling 10 |
| RIN2 | Ras and Rab interactor 2 |
| RNF19B | ring finger protein 19B |
| RNF2 | ring finger protein 2 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SH2B1 | SH2B adaptor protein 1 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC25A17 | solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SOAT1 | sterol O-acyltransferase 1 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| STAB1 | stabilin 1 |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| TCHH | trichohyalin |
| TGFB2 | transforming growth factor, beta 2 |
| TMEM80 | transmembrane protein 80 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| USP24 | ubiquitin specific peptidase 24 |
| USP36 | ubiquitin specific peptidase 36 |
| VEGFA | vascular endothelial growth factor A |
| YIPF4 | Yip1 domain family, member 4 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZHX3 | zinc fingers and homeoboxes 3 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF492 | zinc finger protein 492 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
| Symbol | Name |
|---|---|
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ABLIM3 | actin binding LIM protein family, member 3 |
| ACTL8 | actin-like 8 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| AMDHD2 | amidohydrolase domain containing 2 |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| APOD | apolipoprotein D |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARRB1 | arrestin, beta 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BCORL1 | BCL6 corepressor-like 1 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| CASD1 | CAS1 domain containing 1 |
| CASZ1 | castor zinc finger 1 |
| CBR1 | carbonyl reductase 1 |
| CBR4 | carbonyl reductase 4 |
| CCDC85C | coiled-coil domain containing 85C |
| CDK20 | cyclin-dependent kinase 20 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CORT | cortistatin |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CRLF1 | cytokine receptor-like factor 1 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| DNM1 | dynamin 1 |
| EML4 | echinoderm microtubule associated protein like 4 |
| ENO2 | enolase 2 (gamma, neuronal) |
| EPHA2 | EPH receptor A2 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FKBP5 | FK506 binding protein 5 |
| GAS8 | growth arrest-specific 8 |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| HSPA2 | heat shock 70kDa protein 2 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| IGFLR1 | IGF-like family receptor 1 |
| INCENP | inner centromere protein antigens 135/155kDa |
| IPO8 | importin 8 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KIAA0894 | KIAA0894 protein |
| LMNB2 | lamin B2 |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MFAP2 | microfibrillar-associated protein 2 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MTHFS | 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NTHL1 | nth endonuclease III-like 1 (E. coli) |
| OLFML3 | olfactomedin-like 3 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PMM1 | phosphomannomutase 1 |
| POLR2F | polymerase (RNA) II (DNA directed) polypeptide F |
| PROS1 | protein S (alpha) |
| PTCD2 | pentatricopeptide repeat domain 2 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB30 | RAB30, member RAS oncogene family |
| RAD54L | RAD54-like (S. cerevisiae) |
| RFTN1 | raftlin, lipid raft linker 1 |
| RNF170 | ring finger protein 170 |
| S100A4 | S100 calcium binding protein A4 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SH2D4A | SH2 domain containing 4A |
| SIRT6 | sirtuin 6 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC46A3 | solute carrier family 46, member 3 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SPATA2L | spermatogenesis associated 2-like |
| SREK1IP1 | SREK1-interacting protein 1 |
| STAG3 | stromal antigen 3 |
| SYCP2 | synaptonemal complex protein 2 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TBC1D17 | TBC1 domain family, member 17 |
| TBC1D19 | TBC1 domain family, member 19 |
| TNRC6B | trinucleotide repeat containing 6B |
| TUBA3C | tubulin, alpha 3c |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 |
| UBQLN4 | ubiquilin 4 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| VWA1 | von Willebrand factor A domain containing 1 |
| WARS2 | tryptophanyl tRNA synthetase 2, mitochondrial |
| XAB2 | XPA binding protein 2 |
| ZMYM1 | zinc finger, MYM-type 1 |
| ZNF408 | zinc finger protein 408 |
| ZNF747 | zinc finger protein 747 |
