| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the proadifen-5807 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| ARTN | artemin |
| ATF3 | activating transcription factor 3 |
| BAIAP2 | BAI1-associated protein 2 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BICC1 | BicC family RNA binding protein 1 |
| BRWD1 | bromodomain and WD repeat domain containing 1 |
| C4BPA | complement component 4 binding protein, alpha |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CCNT2 | cyclin T2 |
| CD58 | CD58 molecule |
| CDC42 | cell division cycle 42 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CHST3 | carbohydrate (chondroitin 6) sulfotransferase 3 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CTSF | cathepsin F |
| CTSG | cathepsin G |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCR6 | chemokine (C-X-C motif) receptor 6 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DUSP1 | dual specificity phosphatase 1 |
| EGR1 | early growth response 1 |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) |
| ELN | elastin |
| EML2 | echinoderm microtubule associated protein like 2 |
| FAM50B | family with sequence similarity 50, member B |
| FBXO41 | F-box protein 41 |
| FOXO4 | forkhead box O4 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GATA4 | GATA binding protein 4 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GSTM5 | glutathione S-transferase mu 5 |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IL6 | interleukin 6 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| JUND | jun D proto-oncogene |
| KCNJ1 | potassium channel, inwardly rectifying subfamily J, member 1 |
| KIAA0895 | KIAA0895 |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| KRT6B | keratin 6B, type II |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAN2A2 | mannosidase, alpha, class 2A, member 2 |
| MAPT | microtubule-associated protein tau |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NPTXR | neuronal pentraxin receptor |
| NPY4R | neuropeptide Y receptor Y4 |
| NRP1 | neuropilin 1 |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| OR52A1 | olfactory receptor, family 52, subfamily A, member 1 |
| OSBPL10 | oxysterol binding protein-like 10 |
| PC | pyruvate carboxylase |
| PCDH12 | protocadherin 12 |
| PCNX | pecanex homolog (Drosophila) |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLK3 | polo-like kinase 3 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRMT2IP | PRMT2 interacting protein |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RARG | retinoic acid receptor, gamma |
| RASA2 | RAS p21 protein activator 2 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RRAGB | Ras-related GTP binding B |
| RWDD2A | RWD domain containing 2A |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC18A2 | solute carrier family 18 (vesicular monoamine transporter), member 2 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SMAD7 | SMAD family member 7 |
| SOS1 | son of sevenless homolog 1 (Drosophila) |
| STK4 | serine/threonine kinase 4 |
| TBCD | tubulin folding cofactor D |
| TEX40 | testis expressed 40 |
| TFEB | transcription factor EB |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TPM1 | tropomyosin 1 (alpha) |
| TRPA1 | transient receptor potential cation channel, subfamily A, member 1 |
| TSC22D4 | TSC22 domain family, member 4 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| UNC119 | unc-119 homolog (C. elegans) |
| YIPF4 | Yip1 domain family, member 4 |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| Symbol | Name |
|---|---|
| ACSF2 | acyl-CoA synthetase family member 2 |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ADAM15 | ADAM metallopeptidase domain 15 |
| AES | amino-terminal enhancer of split |
| ANAPC2 | anaphase promoting complex subunit 2 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| ATP13A2 | ATPase type 13A2 |
| C12ORF43 | chromosome 12 open reading frame 43 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CEP70 | centrosomal protein 70kDa |
| CFAP69 | cilia and flagella associated protein 69 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CNTNAP1 | contactin associated protein 1 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DCLRE1A | DNA cross-link repair 1A |
| DCPS | decapping enzyme, scavenger |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DHTKD1 | dehydrogenase E1 and transketolase domain containing 1 |
| ECH1 | enoyl CoA hydratase 1, peroxisomal |
| EN2 | engrailed homeobox 2 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERCC2 | excision repair cross-complementation group 2 |
| FADS3 | fatty acid desaturase 3 |
| FAM193A | family with sequence similarity 193, member A |
| FIG4 | FIG4 phosphoinositide 5-phosphatase |
| FKBPL | FK506 binding protein like |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| FZD3 | frizzled class receptor 3 |
| GALNS | galactosamine (N-acetyl)-6-sulfatase |
| GAMT | guanidinoacetate N-methyltransferase |
| GRPR | gastrin-releasing peptide receptor |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOXA2 | homeobox A2 |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| IL17RB | interleukin 17 receptor B |
| IMPACT | impact RWD domain protein |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KDM5C | lysine (K)-specific demethylase 5C |
| LAMA5 | laminin, alpha 5 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LOC730101 | uncharacterized LOC730101 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) |
| MAP1S | microtubule-associated protein 1S |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 |
| MED9 | mediator complex subunit 9 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MICALL2 | MICAL-like 2 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MTHFS | 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) |
| NBAS | neuroblastoma amplified sequence |
| NCS1 | neuronal calcium sensor 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NINL | ninein-like |
| NLRX1 | NLR family member X1 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NUBPL | nucleotide binding protein-like |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| ORC1 | origin recognition complex, subunit 1 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDZD2 | PDZ domain containing 2 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
| PTCD2 | pentatricopeptide repeat domain 2 |
| RARS | arginyl-tRNA synthetase |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| S100A9 | S100 calcium binding protein A9 |
| SCRN3 | secernin 3 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SELENBP1 | selenium binding protein 1 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SLC35G2 | solute carrier family 35, member G2 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 |
| SMYD5 | SMYD family member 5 |
| SNIP1 | Smad nuclear interacting protein 1 |
| SPEG | SPEG complex locus |
| STEAP4 | STEAP family member 4 |
| STX17 | syntaxin 17 |
| TDRD7 | tudor domain containing 7 |
| TMEM242 | transmembrane protein 242 |
| UBAC1 | UBA domain containing 1 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF629 | zinc finger protein 629 |
| ZNF654 | zinc finger protein 654 |
