probucol-592 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the probucol-592 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABHD2 abhydrolase domain containing 2
ACAN aggrecan
ADAM19 ADAM metallopeptidase domain 19
AEN apoptosis enhancing nuclease
AGGF1 angiogenic factor with G patch and FHA domains 1
AGMAT agmatine ureohydrolase (agmatinase)
AKIP1 A kinase (PRKA) interacting protein 1
AQP6 aquaporin 6, kidney specific
ARHGAP32 Rho GTPase activating protein 32
ASCL1 achaete-scute family bHLH transcription factor 1
ATAD2B ATPase family, AAA domain containing 2B
ATN1 atrophin 1
ATP2A3 ATPase, Ca++ transporting, ubiquitous
AVL9 AVL9 homolog (S. cerevisiase)
BBC3 BCL2 binding component 3
BCR breakpoint cluster region
C6 complement component 6
C7ORF43 chromosome 7 open reading frame 43
CC2D1A coiled-coil and C2 domain containing 1A
CD44 CD44 molecule (Indian blood group)
CENPT centromere protein T
CNTD2 cyclin N-terminal domain containing 2
COL18A1 collagen, type XVIII, alpha 1
DAPK3 death-associated protein kinase 3
DCP1A decapping mRNA 1A
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DUS2 dihydrouridine synthase 2
EGR3 early growth response 3
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOSC9 exosome component 9
FAM107A family with sequence similarity 107, member A
FGFR1 fibroblast growth factor receptor 1
FOXC1 forkhead box C1
FXR2 fragile X mental retardation, autosomal homolog 2
GSK3A glycogen synthase kinase 3 alpha
HAP1 huntingtin-associated protein 1
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HLA-B major histocompatibility complex, class I, B
HLA-G major histocompatibility complex, class I, G
HNF1A HNF1 homeobox A
IL13RA1 interleukin 13 receptor, alpha 1
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LHX2 LIM homeobox 2
LMF2 lipase maturation factor 2
LRP6 low density lipoprotein receptor-related protein 6
LRRC41 leucine rich repeat containing 41
MALL mal, T-cell differentiation protein-like
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAPT microtubule-associated protein tau
MBP myelin basic protein
MBTPS1 membrane-bound transcription factor peptidase, site 1
MCAM melanoma cell adhesion molecule
MMP17 matrix metallopeptidase 17 (membrane-inserted)
NCKIPSD NCK interacting protein with SH3 domain
NPPA natriuretic peptide A
NRP1 neuropilin 1
OCRL oculocerebrorenal syndrome of Lowe
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PHKA2 phosphorylase kinase, alpha 2 (liver)
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PRB1 proline-rich protein BstNI subfamily 1
PRPH peripherin
PRRC2A proline-rich coiled-coil 2A
RAD54L RAD54-like (S. cerevisiae)
RPS2 ribosomal protein S2
RPS4Y1 ribosomal protein S4, Y-linked 1
RUNX1 runt-related transcription factor 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SCAMP1 secretory carrier membrane protein 1
SH3PXD2A SH3 and PX domains 2A
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC38A7 solute carrier family 38, member 7
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SZRD1 SUZ RNA binding domain containing 1
TIMP3 TIMP metallopeptidase inhibitor 3
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRIM3 tripartite motif containing 3
UCHL5 ubiquitin carboxyl-terminal hydrolase L5
UMPS uridine monophosphate synthetase
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF43 zinc finger protein 43
ZNF783 zinc finger family member 783
ZNHIT2 zinc finger, HIT-type containing 2
ZSCAN5A zinc finger and SCAN domain containing 5A

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACD adrenocortical dysplasia homolog (mouse)
ACSF2 acyl-CoA synthetase family member 2
ACTC1 actin, alpha, cardiac muscle 1
ADAMTSL4 ADAMTS-like 4
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
APCS amyloid P component, serum
APH1A APH1A gamma secretase subunit
ARSE arylsulfatase E (chondrodysplasia punctata 1)
ATG10 autophagy related 10
AXIN1 axin 1
BCORL1 BCL6 corepressor-like 1
BFAR bifunctional apoptosis regulator
C16ORF59 chromosome 16 open reading frame 59
CA7 carbonic anhydrase VII
CARTPT CART prepropeptide
CHRM4 cholinergic receptor, muscarinic 4
CIDEB cell death-inducing DFFA-like effector b
CLEC4E C-type lectin domain family 4, member E
COBL cordon-bleu WH2 repeat protein
CRYAB crystallin, alpha B
CSN2 casein beta
CXCL9 chemokine (C-X-C motif) ligand 9
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DCLRE1A DNA cross-link repair 1A
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DMBT1 deleted in malignant brain tumors 1
DOK5 docking protein 5
DPEP1 dipeptidase 1 (renal)
DRP2 dystrophin related protein 2
DUSP22 dual specificity phosphatase 22
DUSP8 dual specificity phosphatase 8
ECM1 extracellular matrix protein 1
EFNA1 ephrin-A1
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
FAM171A1 family with sequence similarity 171, member A1
FAM178A family with sequence similarity 178, member A
FOXD1 forkhead box D1
FUZ fuzzy planar cell polarity protein
GOLGA8B golgin A8 family, member B
GP6 glycoprotein VI (platelet)
GPATCH2L G patch domain containing 2-like
GPX2 glutathione peroxidase 2
GSTCD glutathione S-transferase, C-terminal domain containing
H2AFY2 H2A histone family, member Y2
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXC5 homeobox C5
IL19 interleukin 19
IRF9 interferon regulatory factor 9
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3
KIF13B kinesin family member 13B
KRT1 keratin 1, type II
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LIN7B lin-7 homolog B (C. elegans)
LOC642236 FSHD region gene 1 pseudogene
LRRC15 leucine rich repeat containing 15
LUZP4 leucine zipper protein 4
MEFV Mediterranean fever
MX2 MX dynamin-like GTPase 2
MYO1E myosin IE
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
NXF2 nuclear RNA export factor 2
NXPH3 neurexophilin 3
OR10J1 olfactory receptor, family 10, subfamily J, member 1
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OVGP1 oviductal glycoprotein 1, 120kDa
PALM paralemmin
PDE7B phosphodiesterase 7B
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PMEL premelanosome protein
PRPH2 peripherin 2 (retinal degeneration, slow)
PTPRT protein tyrosine phosphatase, receptor type, T
RAB4B RAB4B, member RAS oncogene family
RABL6 RAB, member RAS oncogene family-like 6
RIC3 RIC3 acetylcholine receptor chaperone
RORC RAR-related orphan receptor C
S100A9 S100 calcium binding protein A9
S100PBP S100P binding protein
SEC14L5 SEC14-like 5 (S. cerevisiae)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SMYD5 SMYD family member 5
STAT4 signal transducer and activator of transcription 4
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TMEM206 transmembrane protein 206
TMPRSS5 transmembrane protease, serine 5
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18
TNS2 tensin 2
TNS4 tensin 4
TUBA4B tubulin, alpha 4b
UBTD1 ubiquitin domain containing 1
VAV1 vav 1 guanine nucleotide exchange factor
VIPR1 vasoactive intestinal peptide receptor 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
XYLT2 xylosyltransferase II
ZBTB22 zinc finger and BTB domain containing 22
ZFP36 ZFP36 ring finger protein