procainamide-1263 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the procainamide-1263 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
ADAM17 ADAM metallopeptidase domain 17
AGGF1 angiogenic factor with G patch and FHA domains 1
AKTIP AKT interacting protein
ANKRD6 ankyrin repeat domain 6
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARL4C ADP-ribosylation factor-like 4C
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATP11A ATPase, class VI, type 11A
ATP13A3 ATPase type 13A3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
ATP7A ATPase, Cu++ transporting, alpha polypeptide
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
C17ORF80 chromosome 17 open reading frame 80
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CAMKMT calmodulin-lysine N-methyltransferase
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CDC14A cell division cycle 14A
CEP290 centrosomal protein 290kDa
CNTLN centlein, centrosomal protein
COL15A1 collagen, type XV, alpha 1
DBT dihydrolipoamide branched chain transacylase E2
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
EML3 echinoderm microtubule associated protein like 3
EML4 echinoderm microtubule associated protein like 4
ERCC4 excision repair cross-complementation group 4
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM188A family with sequence similarity 188, member A
FAM63B family with sequence similarity 63, member B
FOXD1 forkhead box D1
FZD6 frizzled class receptor 6
GIMAP6 GTPase, IMAP family member 6
GLCE glucuronic acid epimerase
GPR19 G protein-coupled receptor 19
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HIST1H2BD histone cluster 1, H2bd
HSPA4 heat shock 70kDa protein 4
ICAM1 intercellular adhesion molecule 1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
INPP5K inositol polyphosphate-5-phosphatase K
KAZN kazrin, periplakin interacting protein
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
LEFTY2 left-right determination factor 2
MAP4 microtubule-associated protein 4
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MTMR1 myotubularin related protein 1
MYOF myoferlin
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NFRKB nuclear factor related to kappaB binding protein
NKRF NFKB repressing factor
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRP1 neuropilin 1
NUP160 nucleoporin 160kDa
PAOX polyamine oxidase (exo-N4-amino)
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDE4DIP phosphodiesterase 4D interacting protein
PHC1 polyhomeotic homolog 1 (Drosophila)
PLS1 plastin 1
PNRC1 proline-rich nuclear receptor coactivator 1
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1
PRUNE prune exopolyphosphatase
PSEN1 presenilin 1
PTAFR platelet-activating factor receptor
QKI QKI, KH domain containing, RNA binding
RAB23 RAB23, member RAS oncogene family
RALGAPA1 Ral GTPase activating protein, alpha subunit 1 (catalytic)
RC3H2 ring finger and CCCH-type domains 2
RECQL RecQ helicase-like
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
SALL2 spalt-like transcription factor 2
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SGSM3 small G protein signaling modulator 3
SOS2 son of sevenless homolog 2 (Drosophila)
SPAG4 sperm associated antigen 4
SPN sialophorin
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SRSF11 serine/arginine-rich splicing factor 11
TCTN1 tectonic family member 1
TFIP11 tuftelin interacting protein 11
TLK1 tousled-like kinase 1
TM2D1 TM2 domain containing 1
TMOD3 tropomodulin 3 (ubiquitous)
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
YY1 YY1 transcription factor
ZDHHC18 zinc finger, DHHC-type containing 18
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF133 zinc finger protein 133
ZNF254 zinc finger protein 254

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ADTRP androgen-dependent TFPI-regulating protein
AES amino-terminal enhancer of split
ALPK1 alpha-kinase 1
ARHGAP10 Rho GTPase activating protein 10
ARID5A AT rich interactive domain 5A (MRF1-like)
ASAP1-IT1 ASAP1 intronic transcript 1
ASGR2 asialoglycoprotein receptor 2
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
C5 complement component 5
C5AR1 complement component 5a receptor 1
CCDC94 coiled-coil domain containing 94
CDC37L1 cell division cycle 37-like 1
CDK3 cyclin-dependent kinase 3
CENPT centromere protein T
CEP170B centrosomal protein 170B
CEP97 centrosomal protein 97kDa
CIDEB cell death-inducing DFFA-like effector b
CNN2 calponin 2
COG4 component of oligomeric golgi complex 4
CPTP ceramide-1-phosphate transfer protein
CTDNEP1 CTD nuclear envelope phosphatase 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CXORF21 chromosome X open reading frame 21
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DEPTOR DEP domain containing MTOR-interacting protein
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DTX4 deltex 4, E3 ubiquitin ligase
DUSP8 dual specificity phosphatase 8
E4F1 E4F transcription factor 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM184A family with sequence similarity 184, member A
FBRS fibrosin
FGGY FGGY carbohydrate kinase domain containing
FKBP14 FK506 binding protein 14, 22 kDa
FURIN furin (paired basic amino acid cleaving enzyme)
FUZ fuzzy planar cell polarity protein
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GMPPB GDP-mannose pyrophosphorylase B
GPSM3 G-protein signaling modulator 3
GTF2IRD1 GTF2I repeat domain containing 1
HIRA histone cell cycle regulator
HP haptoglobin
IL24 interleukin 24
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
IP6K1 inositol hexakisphosphate kinase 1
ITGB7 integrin, beta 7
JUNB jun B proto-oncogene
KLF13 Kruppel-like factor 13
LRRC37A3 leucine rich repeat containing 37, member A3
MAPK12 mitogen-activated protein kinase 12
MAPKBP1 mitogen-activated protein kinase binding protein 1
MED9 mediator complex subunit 9
METTL8 methyltransferase like 8
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MXD3 MAX dimerization protein 3
NPDC1 neural proliferation, differentiation and control, 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PIGH phosphatidylinositol glycan anchor biosynthesis, class H
PNOC prepronociceptin
POLH polymerase (DNA directed), eta
POMZP3 POM121 and ZP3 fusion
PPCS phosphopantothenoylcysteine synthetase
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RHOBTB2 Rho-related BTB domain containing 2
RNF2 ring finger protein 2
RPL23AP7 ribosomal protein L23a pseudogene 7
SASH3 SAM and SH3 domain containing 3
SHPK sedoheptulokinase
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SLPI secretory leukocyte peptidase inhibitor
SMYD5 SMYD family member 5
TBC1D17 TBC1 domain family, member 17
TCTA T-cell leukemia translocation altered
TFE3 transcription factor binding to IGHM enhancer 3
THEM6 thioesterase superfamily member 6
THOP1 thimet oligopeptidase 1
TKFC triokinase/FMN cyclase
TM7SF3 transmembrane 7 superfamily member 3
TOM1 target of myb1 (chicken)
TRIM5 tripartite motif containing 5
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TRPS1 trichorhinophalangeal syndrome I
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UNC13B unc-13 homolog B (C. elegans)
UNC93B1 unc-93 homolog B1 (C. elegans)
VILL villin-like
ZBTB48 zinc finger and BTB domain containing 48
ZNF223 zinc finger protein 223
ZNF669 zinc finger protein 669
ZNF721 zinc finger protein 721
ZNF816 zinc finger protein 816