procainamide-4602 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the procainamide-4602 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACO2 aconitase 2, mitochondrial
AMPH amphiphysin
ANK1 ankyrin 1, erythrocytic
APC2 adenomatosis polyposis coli 2
ARHGAP26 Rho GTPase activating protein 26
ARHGEF10 Rho guanine nucleotide exchange factor (GEF) 10
ASCL1 achaete-scute family bHLH transcription factor 1
C17ORF53 chromosome 17 open reading frame 53
C1QTNF3 C1q and tumor necrosis factor related protein 3
CARD10 caspase recruitment domain family, member 10
CCDC87 coiled-coil domain containing 87
CCR3 chemokine (C-C motif) receptor 3
CD101 CD101 molecule
CLEC1A C-type lectin domain family 1, member A
CRLF1 cytokine receptor-like factor 1
CSHL1 chorionic somatomammotropin hormone-like 1
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DSC1 desmocollin 1
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B
EBF2 early B-cell factor 2
EDA ectodysplasin A
EGR1 early growth response 1
EPX eosinophil peroxidase
ESR1 estrogen receptor 1
ETV7 ets variant 7
FAM186A family with sequence similarity 186, member A
FLJ11292
FOXD2 forkhead box D2
FXYD2 FXYD domain containing ion transport regulator 2
GLRA2 glycine receptor, alpha 2
GPX3 glutathione peroxidase 3
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRM1 glutamate receptor, metabotropic 1
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene)
HEXIM1 hexamethylene bis-acetamide inducible 1
HOXD13 homeobox D13
HOXD3 homeobox D3
HOXD9 homeobox D9
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IFNA1 interferon, alpha 1
IGH immunoglobulin heavy locus
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
KIF25-AS1 KIF25 antisense RNA 1
LGALS9 lectin, galactoside-binding, soluble, 9
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LOC390998 ribosomal protein L10 pseudogene
MAB21L1 mab-21-like 1 (C. elegans)
MAN1C1 mannosidase, alpha, class 1C, member 1
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
METTL7A methyltransferase like 7A
MMP10 matrix metallopeptidase 10
MUC4 mucin 4, cell surface associated
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYO15A myosin XVA
MYOZ2 myozenin 2
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NCR2 natural cytotoxicity triggering receptor 2
NIPAL2 NIPA-like domain containing 2
NKX3-2 NK3 homeobox 2
NMUR1 neuromedin U receptor 1
NPFFR1 neuropeptide FF receptor 1
PDCD1LG2 programmed cell death 1 ligand 2
PDE10A phosphodiesterase 10A
PDGFB platelet-derived growth factor beta polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3
PLCH1 phospholipase C, eta 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POU1F1 POU class 1 homeobox 1
POU3F3 POU class 3 homeobox 3
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRB1 proline-rich protein BstNI subfamily 1
PSG9 pregnancy specific beta-1-glycoprotein 9
RAB6B RAB6B, member RAS oncogene family
RALYL RALY RNA binding protein-like
RBMS2 RNA binding motif, single stranded interacting protein 2
RNF122 ring finger protein 122
RPH3AL rabphilin 3A-like (without C2 domains)
RTN1 reticulon 1
RUNDC3B RUN domain containing 3B
SCN10A sodium channel, voltage gated, type X alpha subunit
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
SLC44A1 solute carrier family 44 (choline transporter), member 1
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
STRN striatin, calmodulin binding protein
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TAPBPL TAP binding protein-like
TBL1Y transducin (beta)-like 1, Y-linked
TMEM176B transmembrane protein 176B
TRD T cell receptor delta locus
TSPY1 testis specific protein, Y-linked 1
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
ZC3H7B zinc finger CCCH-type containing 7B
ZNF467 zinc finger protein 467

decreased expression

Symbol Name
AARS alanyl-tRNA synthetase
AARSD1 alanyl-tRNA synthetase domain containing 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABHD17B abhydrolase domain containing 17B
ABLIM3 actin binding LIM protein family, member 3
AKIP1 A kinase (PRKA) interacting protein 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
AP3B1 adaptor-related protein complex 3, beta 1 subunit
APOLD1 apolipoprotein L domain containing 1
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
C1ORF159 chromosome 1 open reading frame 159
CA9 carbonic anhydrase IX
CDADC1 cytidine and dCMP deaminase domain containing 1
CDC37L1 cell division cycle 37-like 1
CGA glycoprotein hormones, alpha polypeptide
CGREF1 cell growth regulator with EF-hand domain 1
CHD8 chromodomain helicase DNA binding protein 8
CISH cytokine inducible SH2-containing protein
CLDN4 claudin 4
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
DHRS11 dehydrogenase/reductase (SDR family) member 11
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DIXDC1 DIX domain containing 1
DNAL4 dynein, axonemal, light chain 4
DTX2 deltex 2, E3 ubiquitin ligase
FAM222B family with sequence similarity 222, member B
FAM69A family with sequence similarity 69, member A
FGD1 FYVE, RhoGEF and PH domain containing 1
GPALPP1 GPALPP motifs containing 1
GPR176 G protein-coupled receptor 176
GPR3 G protein-coupled receptor 3
GTF2I general transcription factor IIi
HIRA histone cell cycle regulator
HOXA1 homeobox A1
HYAL2 hyaluronoglucosaminidase 2
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
INTS9 integrator complex subunit 9
KCTD20 potassium channel tetramerization domain containing 20
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KIAA0753 KIAA0753
KIAA1456 KIAA1456
KIFC1 kinesin family member C1
KLF7 Kruppel-like factor 7 (ubiquitous)
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LMCD1 LIM and cysteine-rich domains 1
LRRC61 leucine rich repeat containing 61
MAST3 microtubule associated serine/threonine kinase 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
NAG18 NAG18 mRNA
NCAPG2 non-SMC condensin II complex, subunit G2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PARP16 poly (ADP-ribose) polymerase family, member 16
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PEG3 paternally expressed 3
PEX26 peroxisomal biogenesis factor 26
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
POR P450 (cytochrome) oxidoreductase
PSAT1 phosphoserine aminotransferase 1
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF170 ring finger protein 170
RNF31 ring finger protein 31
RRAGB Ras-related GTP binding B
RRP1 ribosomal RNA processing 1
SAYSD1 SAYSVFN motif domain containing 1
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SH3BGR SH3 domain binding glutamate-rich protein
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLITRK5 SLIT and NTRK-like family, member 5
SOD3 superoxide dismutase 3, extracellular
SREBF2 sterol regulatory element binding transcription factor 2
STARD3 StAR-related lipid transfer (START) domain containing 3
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TH tyrosine hydroxylase
THBS3 thrombospondin 3
TMEM8A transmembrane protein 8A
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSPAN1 tetraspanin 1
TTLL7 tubulin tyrosine ligase-like family member 7
ULBP2 UL16 binding protein 2
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR19 WD repeat domain 19
WDR25 WD repeat domain 25
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
YY2 YY2 transcription factor
ZNF197 zinc finger protein 197
ZNF227 zinc finger protein 227
ZNF276 zinc finger protein 276
ZNF33B zinc finger protein 33B
ZNF747 zinc finger protein 747