procaine-1674 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the procaine-1674 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADGRG1 adhesion G protein-coupled receptor G1
ADGRG2 adhesion G protein-coupled receptor G2
AMPD3 adenosine monophosphate deaminase 3
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ARR3 arrestin 3, retinal (X-arrestin)
ARTN artemin
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATXN2L ataxin 2-like
BTBD7 BTB (POZ) domain containing 7
C21ORF2 chromosome 21 open reading frame 2
C3 complement component 3
CD58 CD58 molecule
CDON cell adhesion associated, oncogene regulated
CGREF1 cell growth regulator with EF-hand domain 1
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CNGB3 cyclic nucleotide gated channel beta 3
CRIP1 cysteine-rich protein 1 (intestinal)
CROCC ciliary rootlet coiled-coil, rootletin
CST6 cystatin E/M
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DOK4 docking protein 4
EGFL7 EGF-like-domain, multiple 7
ELOVL2 ELOVL fatty acid elongase 2
EPHA5 EPH receptor A5
ERAP1 endoplasmic reticulum aminopeptidase 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
HIST1H3I histone cluster 1, H3i
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
HR hair growth associated
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
IDS iduronate 2-sulfatase
IFT54 intraflagellar transport 54
IRF1 interferon regulatory factor 1
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KDM4C lysine (K)-specific demethylase 4C
KDM8 lysine (K)-specific demethylase 8
LAT2 linker for activation of T cells family, member 2
MAP4 microtubule-associated protein 4
MAPK7 mitogen-activated protein kinase 7
MARK4 MAP/microtubule affinity-regulating kinase 4
MASP2 mannan-binding lectin serine peptidase 2
MBOAT7 membrane bound O-acyltransferase domain containing 7
MED25 mediator complex subunit 25
METTL16 methyltransferase like 16
MPZ myelin protein zero
MST1 macrophage stimulating 1
MZT2B mitotic spindle organizing protein 2B
NCAPH2 non-SMC condensin II complex, subunit H2
NDRG4 NDRG family member 4
NMT2 N-myristoyltransferase 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHTF2 putative homeodomain transcription factor 2
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PRPH peripherin
PTGES prostaglandin E synthase
PTN pleiotrophin
PTRF polymerase I and transcript release factor
RAB28 RAB28, member RAS oncogene family
RANBP3 RAN binding protein 3
RASAL2 RAS protein activator like 2
RGS10 regulator of G-protein signaling 10
RNF126P1 ring finger protein 126 pseudogene 1
SAFB scaffold attachment factor B
SH2B1 SH2B adaptor protein 1
SLC12A9 solute carrier family 12, member 9
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLIT2 slit homolog 2 (Drosophila)
SMG6 SMG6 nonsense mediated mRNA decay factor
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNW1 SNW domain containing 1
SOCS1 suppressor of cytokine signaling 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
STRA6 stimulated by retinoic acid 6
SYN2 synapsin II
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TMEM63A transmembrane protein 63A
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TP53I11 tumor protein p53 inducible protein 11
TPMT thiopurine S-methyltransferase
TSKS testis-specific serine kinase substrate
TSNAXIP1 translin-associated factor X interacting protein 1
TSPAN2 tetraspanin 2
TSPAN9 tetraspanin 9
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
ZER1 zyg-11 related, cell cycle regulator
ZFPL1 zinc finger protein-like 1
ZMYM4 zinc finger, MYM-type 4
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
AHDC1 AT hook, DNA binding motif, containing 1
AKR1C3 aldo-keto reductase family 1, member C3
ALS2CL ALS2 C-terminal like
ANKRD11 ankyrin repeat domain 11
AP1B1 adaptor-related protein complex 1, beta 1 subunit
ARHGAP11A Rho GTPase activating protein 11A
ATG9A autophagy related 9A
BBC3 BCL2 binding component 3
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C1ORF216 chromosome 1 open reading frame 216
CAPRIN2 caprin family member 2
CCDC88C coiled-coil domain containing 88C
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CISH cytokine inducible SH2-containing protein
CLEC16A C-type lectin domain family 16, member A
COL4A5 collagen, type IV, alpha 5
CTSC cathepsin C
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DDIT3 DNA-damage-inducible transcript 3
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DSCAM Down syndrome cell adhesion molecule
DUSP8 dual specificity phosphatase 8
EFHD1 EF-hand domain family, member D1
EGLN3 egl-9 family hypoxia-inducible factor 3
EVPL envoplakin
FAAH fatty acid amide hydrolase
FAM13B family with sequence similarity 13, member B
FASTKD5 FAST kinase domains 5
FLJ22184
GMEB1 glucocorticoid modulatory element binding protein 1
GUSBP3 glucuronidase, beta pseudogene 3
HCFC2 host cell factor C2
HEATR3 HEAT repeat containing 3
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIRA histone cell cycle regulator
HMOX1 heme oxygenase 1
ICK intestinal cell (MAK-like) kinase
IPO8 importin 8
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITPKC inositol-trisphosphate 3-kinase C
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1
KRT86 keratin 86, type II
LAMB3 laminin, beta 3
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MPI mannose phosphate isomerase
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MSRA methionine sulfoxide reductase A
MT1H metallothionein 1H
MTCL1 microtubule crosslinking factor 1
MTMR6 myotubularin related protein 6
MYO9A myosin IXA
NEO1 neogenin 1
NPIPB15 nuclear pore complex interacting protein family, member B15
PARG poly (ADP-ribose) glycohydrolase
PDZRN3 PDZ domain containing ring finger 3
PHC2 polyhomeotic homolog 2 (Drosophila)
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
PTK6 protein tyrosine kinase 6
PYCRL pyrroline-5-carboxylate reductase-like
RAB3A RAB3A, member RAS oncogene family
RBM42 RNA binding motif protein 42
RCOR3 REST corepressor 3
REPS2 RALBP1 associated Eps domain containing 2
RLF rearranged L-myc fusion
RPAP1 RNA polymerase II associated protein 1
RPH3AL rabphilin 3A-like (without C2 domains)
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SCML2 sex comb on midleg-like 2 (Drosophila)
SH2D4A SH2 domain containing 4A
SKA1 spindle and kinetochore associated complex subunit 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC46A3 solute carrier family 46, member 3
SNHG20 small nucleolar RNA host gene 20
STAG3 stromal antigen 3
STBD1 starch binding domain 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM62 transmembrane protein 62
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TOM1 target of myb1 (chicken)
TPST2 tyrosylprotein sulfotransferase 2
ULBP2 UL16 binding protein 2
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
YEATS2 YEATS domain containing 2
YIPF5 Yip1 domain family, member 5
ZNF211 zinc finger protein 211
ZNF268 zinc finger protein 268
ZNF276 zinc finger protein 276
ZNF281 zinc finger protein 281
ZNF573 zinc finger protein 573
ZNF668 zinc finger protein 668
ZNF675 zinc finger protein 675
ZNF696 zinc finger protein 696
ZW10 zw10 kinetochore protein