procaine-1838 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the procaine-1838 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADTRP androgen-dependent TFPI-regulating protein
ANO2 anoctamin 2, calcium activated chloride channel
ARNT aryl hydrocarbon receptor nuclear translocator
ATF6B activating transcription factor 6 beta
BIK BCL2-interacting killer (apoptosis-inducing)
CACTIN cactin, spliceosome C complex subunit
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CD34 CD34 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDR2L cerebellar degeneration-related protein 2-like
CLCN4 chloride channel, voltage-sensitive 4
CLIP2 CAP-GLY domain containing linker protein 2
CNGB3 cyclic nucleotide gated channel beta 3
CNOT4 CCR4-NOT transcription complex, subunit 4
COL4A1 collagen, type IV, alpha 1
CPTP ceramide-1-phosphate transfer protein
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EPS8L3 EPS8-like 3
ERN2 endoplasmic reticulum to nucleus signaling 2
ETV4 ets variant 4
EXTL3 exostosin-like glycosyltransferase 3
F12 coagulation factor XII (Hageman factor)
FAM188A family with sequence similarity 188, member A
FBXL7 F-box and leucine-rich repeat protein 7
FLNC filamin C, gamma
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
FUZ fuzzy planar cell polarity protein
GPALPP1 GPALPP motifs containing 1
GPR137 G protein-coupled receptor 137
GTF3C2 general transcription factor IIIC, polypeptide 2, beta 110kDa
HDLBP high density lipoprotein binding protein
HIST1H3G histone cluster 1, H3g
HLA-DMB major histocompatibility complex, class II, DM beta
HOXD1 homeobox D1
IFT122 intraflagellar transport 122
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
IQCK IQ motif containing K
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KRT81 keratin 81, type II
LAMC2 laminin, gamma 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LPAR1 lysophosphatidic acid receptor 1
MAGED2 melanoma antigen family D2
MAGEF1 melanoma antigen family F1
MAL mal, T-cell differentiation protein
MAP4 microtubule-associated protein 4
MC3R melanocortin 3 receptor
MED25 mediator complex subunit 25
MED28 mediator complex subunit 28
MINK1 misshapen-like kinase 1
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
MMP25 matrix metallopeptidase 25
MNMIP1 manchette microtubule inner protein 1
NAAA N-acylethanolamine acid amidase
NCKIPSD NCK interacting protein with SH3 domain
NDRG2 NDRG family member 2
NEFH neurofilament, heavy polypeptide
NF2 neurofibromin 2 (merlin)
PAX4 paired box 4
PCCA propionyl CoA carboxylase, alpha polypeptide
PEX5 peroxisomal biogenesis factor 5
PHF7 PHD finger protein 7
PHKA2 phosphorylase kinase, alpha 2 (liver)
PIDD1 p53-induced death domain protein 1
PLXNC1 plexin C1
PODNL1 podocan-like 1
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RREB1 ras responsive element binding protein 1
SCAND2P SCAN domain containing 2 pseudogene
SERGEF secretion regulating guanine nucleotide exchange factor
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SMYD5 SMYD family member 5
SNAI1 snail family zinc finger 1
SOX12 SRY (sex determining region Y)-box 12
SOX4 SRY (sex determining region Y)-box 4
SPATA20 spermatogenesis associated 20
SPHK2 sphingosine kinase 2
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
STK11 serine/threonine kinase 11
SUGP1 SURP and G patch domain containing 1
SYNJ1 synaptojanin 1
TBX19 T-box 19
TCP11L1 t-complex 11, testis-specific-like 1
THBS3 thrombospondin 3
TMEM63A transmembrane protein 63A
TPP1 tripeptidyl peptidase I
TRAF3IP3 TRAF3 interacting protein 3
TRIP11 thyroid hormone receptor interactor 11
TTLL1 tubulin tyrosine ligase-like family member 1
TULP3 tubby like protein 3
WNT2B wingless-type MMTV integration site family, member 2B
YTHDC1 YTH domain containing 1
ZBTB20 zinc finger and BTB domain containing 20
ZMYM4 zinc finger, MYM-type 4
ZNF324 zinc finger protein 324
ZNF467 zinc finger protein 467

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACPP acid phosphatase, prostate
ACYP2 acylphosphatase 2, muscle type
ADGRE2 adhesion G protein-coupled receptor E2
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ALPK1 alpha-kinase 1
ANP32A-IT1 ANP32A intronic transcript 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATAD5 ATPase family, AAA domain containing 5
BBS10 Bardet-Biedl syndrome 10
C21ORF91 chromosome 21 open reading frame 91
C3 complement component 3
C4ORF29 chromosome 4 open reading frame 29
CCDC6 coiled-coil domain containing 6
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CGREF1 cell growth regulator with EF-hand domain 1
CHMP6 charged multivesicular body protein 6
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNN2 calponin 2
CNOT6 CCR4-NOT transcription complex, subunit 6
DDA1 DET1 and DDB1 associated 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DEF8 differentially expressed in FDCP 8 homolog (mouse)
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DIXDC1 DIX domain containing 1
DOCK4 dedicator of cytokinesis 4
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
ERCC8 excision repair cross-complementation group 8
GPR63 G protein-coupled receptor 63
GPR65 G protein-coupled receptor 65
GPR85 G protein-coupled receptor 85
GRAMD1B GRAM domain containing 1B
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGSF6 immunoglobulin superfamily, member 6
IL4R interleukin 4 receptor
LACTB2 lactamase, beta 2
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LIMD2 LIM domain containing 2
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRP3 low density lipoprotein receptor-related protein 3
MBTD1 mbt domain containing 1
MDM4 MDM4, p53 regulator
METTL8 methyltransferase like 8
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MYO1E myosin IE
NBEAL2 neurobeachin-like 2
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NIPSNAP3B nipsnap homolog 3B (C. elegans)
NMRK1 nicotinamide riboside kinase 1
NSD1 nuclear receptor binding SET domain protein 1
ODF2 outer dense fiber of sperm tails 2
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PIR pirin (iron-binding nuclear protein)
PITRM1 pitrilysin metallopeptidase 1
PLA2G15 phospholipase A2, group XV
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POLR3F polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
QTRT1 queuine tRNA-ribosyltransferase 1
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RBBP5 retinoblastoma binding protein 5
RBKS ribokinase
RBM42 RNA binding motif protein 42
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RFWD3 ring finger and WD repeat domain 3
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPGR retinitis pigmentosa GTPase regulator
SCYL2 SCY1-like 2 (S. cerevisiae)
SDAD1 SDA1 domain containing 1
SFT2D2 SFT2 domain containing 2
SHPK sedoheptulokinase
SKA1 spindle and kinetochore associated complex subunit 1
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SNHG20 small nucleolar RNA host gene 20
TEC tec protein tyrosine kinase
TESK1 testis-specific kinase 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THAP1 THAP domain containing, apoptosis associated protein 1
TPRA1 transmembrane protein, adipocyte asscociated 1
TRABD TraB domain containing
TRIM25 tripartite motif containing 25
TSC22D1 TSC22 domain family, member 1
TTF2 transcription termination factor, RNA polymerase II
TWISTNB TWIST neighbor
TXLNG taxilin gamma
XAF1 XIAP associated factor 1
ZBED8 zinc finger, BED-type containing 8
ZBTB39 zinc finger and BTB domain containing 39
ZNF10 zinc finger protein 10
ZNF197 zinc finger protein 197
ZNF280D zinc finger protein 280D
ZNF652 zinc finger protein 652
ZNF747 zinc finger protein 747
ZNF804A zinc finger protein 804A