| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the procarbazine-3533 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVR1B | activin A receptor, type IB |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ATF6B | activating transcription factor 6 beta |
| BMP6 | bone morphogenetic protein 6 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C3 | complement component 3 |
| CADM3 | cell adhesion molecule 3 |
| CCDC132 | coiled-coil domain containing 132 |
| CCDC28B | coiled-coil domain containing 28B |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CELF3 | CUGBP, Elav-like family member 3 |
| COLEC12 | collectin sub-family member 12 |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 |
| CYP4A22 | cytochrome P450, family 4, subfamily A, polypeptide 22 |
| DCN | decorin |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DIAPH2-AS1 | DIAPH2 antisense RNA 1 |
| DICER1 | dicer 1, ribonuclease type III |
| DYSF | dysferlin |
| ECE1 | endothelin converting enzyme 1 |
| ENO3 | enolase 3 (beta, muscle) |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| EPS8L1 | EPS8-like 1 |
| ESR1 | estrogen receptor 1 |
| FABP7 | fatty acid binding protein 7, brain |
| FGF18 | fibroblast growth factor 18 |
| FN1 | fibronectin 1 |
| FOXN3 | forkhead box N3 |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| GLB1L | galactosidase, beta 1-like |
| GPR176 | G protein-coupled receptor 176 |
| GRM1 | glutamate receptor, metabotropic 1 |
| GSK3A | glycogen synthase kinase 3 alpha |
| GZMM | granzyme M (lymphocyte met-ase 1) |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IL24 | interleukin 24 |
| INVS | inversin |
| IPCEF1 | interaction protein for cytohesin exchange factors 1 |
| JAM3 | junctional adhesion molecule 3 |
| KLK7 | kallikrein-related peptidase 7 |
| KRT12 | keratin 12, type I |
| KRT17 | keratin 17, type I |
| LAT2 | linker for activation of T cells family, member 2 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LUZP4 | leucine zipper protein 4 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MTMR8 | myotubularin related protein 8 |
| NABP1 | nucleic acid binding protein 1 |
| NKX2-2 | NK2 homeobox 2 |
| NMT2 | N-myristoyltransferase 2 |
| ONECUT1 | one cut homeobox 1 |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| OSBPL10 | oxysterol binding protein-like 10 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PKD2L2 | polycystic kidney disease 2-like 2 |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| PSG3 | pregnancy specific beta-1-glycoprotein 3 |
| PTCRA | pre T-cell antigen receptor alpha |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| PXDC1 | PX domain containing 1 |
| RAB35 | RAB35, member RAS oncogene family |
| RGS4 | regulator of G-protein signaling 4 |
| RPH3A | rabphilin 3A |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SCNN1G | sodium channel, non voltage gated 1 gamma subunit |
| SDC2 | syndecan 2 |
| SLCO1C1 | solute carrier organic anion transporter family, member 1C1 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SNX13 | sorting nexin 13 |
| SULT1E1 | sulfotransferase family 1E, estrogen-preferring, member 1 |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TAOK2 | TAO kinase 2 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TCF20 | transcription factor 20 (AR1) |
| THBS3 | thrombospondin 3 |
| TNC | tenascin C |
| TRIM14 | tripartite motif containing 14 |
| TSPAN2 | tetraspanin 2 |
| TUBA4B | tubulin, alpha 4b |
| TYRP1 | tyrosinase-related protein 1 |
| UPK1B | uroplakin 1B |
| WDR55 | WD repeat domain 55 |
| ZNF44 | zinc finger protein 44 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ACYP2 | acylphosphatase 2, muscle type |
| ANKRD36 | ankyrin repeat domain 36 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARRB1 | arrestin, beta 1 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| BAG4 | BCL2-associated athanogene 4 |
| BAK1 | BCL2-antagonist/killer 1 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCDC25 | coiled-coil domain containing 25 |
| CCNO | cyclin O |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CGA | glycoprotein hormones, alpha polypeptide |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CORT | cortistatin |
| CTC1 | CTS telomere maintenance complex component 1 |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| ECSIT | ECSIT signalling integrator |
| ELMO3 | engulfment and cell motility 3 |
| ERCC5 | excision repair cross-complementation group 5 |
| FAM46C | family with sequence similarity 46, member C |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GPATCH3 | G patch domain containing 3 |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| IRF1 | interferon regulatory factor 1 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KIAA0125 | KIAA0125 |
| KIAA0895 | KIAA0895 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLHL25 | kelch-like family member 25 |
| LAMB2 | laminin, beta 2 (laminin S) |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LIN7A | lin-7 homolog A (C. elegans) |
| LIN7B | lin-7 homolog B (C. elegans) |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LOC730101 | uncharacterized LOC730101 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MFAP2 | microfibrillar-associated protein 2 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NMRK1 | nicotinamide riboside kinase 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLD3 | phospholipase D family, member 3 |
| PMVK | phosphomevalonate kinase |
| PROS1 | protein S (alpha) |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB33B | RAB33B, member RAS oncogene family |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RECQL4 | RecQ protein-like 4 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF170 | ring finger protein 170 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SH2B3 | SH2B adaptor protein 3 |
| SH2D4A | SH2 domain containing 4A |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SPIDR | scaffolding protein involved in DNA repair |
| SSPN | sarcospan |
| STX1A | syntaxin 1A (brain) |
| THOP1 | thimet oligopeptidase 1 |
| TMEM115 | transmembrane protein 115 |
| TMPRSS2 | transmembrane protease, serine 2 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TSPAN5 | tetraspanin 5 |
| TUBA3C | tubulin, alpha 3c |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UBQLN4 | ubiquilin 4 |
| UROS | uroporphyrinogen III synthase |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| VWA1 | von Willebrand factor A domain containing 1 |
| WLS | wntless Wnt ligand secretion mediator |
| ZNF250 | zinc finger protein 250 |
| ZNF324 | zinc finger protein 324 |
| ZNF652 | zinc finger protein 652 |
| ZNF675 | zinc finger protein 675 |
