procyclidine-2991 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the procyclidine-2991 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABHD2 abhydrolase domain containing 2
AFF3 AF4/FMR2 family, member 3
ALS2CL ALS2 C-terminal like
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
APC2 adenomatosis polyposis coli 2
ARL2BP ADP-ribosylation factor-like 2 binding protein
ATP9A ATPase, class II, type 9A
BCAS3 breast carcinoma amplified sequence 3
BEND5 BEN domain containing 5
C9ORF9 chromosome 9 open reading frame 9
CALD1 caldesmon 1
CD300C CD300c molecule
CD58 CD58 molecule
CDK2 cyclin-dependent kinase 2
CLEC4M C-type lectin domain family 4, member M
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CSNK1G1 casein kinase 1, gamma 1
DGCR8 DGCR8 microprocessor complex subunit
DHODH dihydroorotate dehydrogenase (quinone)
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DNAI2 dynein, axonemal, intermediate chain 2
DNPEP aspartyl aminopeptidase
DRD2 dopamine receptor D2
DSTYK dual serine/threonine and tyrosine protein kinase
EDNRB endothelin receptor type B
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FCAR Fc fragment of IgA receptor
FCMR Fc fragment of IgM receptor
FDPS farnesyl diphosphate synthase
FGFBP1 fibroblast growth factor binding protein 1
FHL1 four and a half LIM domains 1
FJX1 four jointed box 1 (Drosophila)
FMO5 flavin containing monooxygenase 5
FXYD2 FXYD domain containing ion transport regulator 2
FYB FYN binding protein
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GRIA3 glutamate receptor, ionotropic, AMPA 3
GZMK granzyme K (granzyme 3; tryptase II)
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HSPB8 heat shock 22kDa protein 8
IFIH1 interferon induced with helicase C domain 1
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IRF5 interferon regulatory factor 5
ITGA8 integrin, alpha 8
KDSR 3-ketodihydrosphingosine reductase
KIF24 kinesin family member 24
KLHL18 kelch-like family member 18
LDLR low density lipoprotein receptor
LIG4 ligase IV, DNA, ATP-dependent
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
MAB21L2 mab-21-like 2 (C. elegans)
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MFAP3L microfibrillar-associated protein 3-like
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MPZL1 myelin protein zero-like 1
MRPS12 mitochondrial ribosomal protein S12
NDRG2 NDRG family member 2
NLRP1 NLR family, pyrin domain containing 1
NOX1 NADPH oxidase 1
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PAX5 paired box 5
PCDHGA8 protocadherin gamma subfamily A, 8
PDE4A phosphodiesterase 4A, cAMP-specific
PDGFB platelet-derived growth factor beta polypeptide
PEX26 peroxisomal biogenesis factor 26
PIGR polymeric immunoglobulin receptor
PLCG1 phospholipase C, gamma 1
PRM1 protamine 1
PTGDR2 prostaglandin D2 receptor 2
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RNF25 ring finger protein 25
ROR1 receptor tyrosine kinase-like orphan receptor 1
SAA3P serum amyloid A3 pseudogene
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SMAD5 SMAD family member 5
SNED1 sushi, nidogen and EGF-like domains 1
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SPN sialophorin
SRCAP Snf2-related CREBBP activator protein
SSBP2 single-stranded DNA binding protein 2
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STK3 serine/threonine kinase 3
TBC1D22B TBC1 domain family, member 22B
TMEM63A transmembrane protein 63A
TNNT3 troponin T type 3 (skeletal, fast)
TRPS1 trichorhinophalangeal syndrome I
USB1 U6 snRNA biogenesis 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZBTB20 zinc finger and BTB domain containing 20
ZNF442 zinc finger protein 442

decreased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADGB androglobin
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANXA2P3 annexin A2 pseudogene 3
BTF3P11 basic transcription factor 3 pseudogene 11
BTF3P12 basic transcription factor 3 pseudogene 12
C14ORF105 chromosome 14 open reading frame 105
C22ORF29 chromosome 22 open reading frame 29
C5AR1 complement component 5a receptor 1
C8ORF44 chromosome 8 open reading frame 44
CABP2 calcium binding protein 2
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CCRL2 chemokine (C-C motif) receptor-like 2
CD79A CD79a molecule, immunoglobulin-associated alpha
CD79B CD79b molecule, immunoglobulin-associated beta
CD9 CD9 molecule
CDK20 cyclin-dependent kinase 20
CDR2L cerebellar degeneration-related protein 2-like
CELP carboxyl ester lipase pseudogene
CEP295 centrosomal protein 295kDa
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CNN1 calponin 1, basic, smooth muscle
CNPY4 canopy FGF signaling regulator 4
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CPNE7 copine VII
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EYA3 EYA transcriptional coactivator and phosphatase 3
FBXL7 F-box and leucine-rich repeat protein 7
FBXO40 F-box protein 40
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPC3 glypican 3
GPR35 G protein-coupled receptor 35
GPRC5C G protein-coupled receptor, class C, group 5, member C
HDAC7 histone deacetylase 7
HIST1H2BN histone cluster 1, H2bn
HOXA2 homeobox A2
IBSP integrin-binding sialoprotein
IRF1 interferon regulatory factor 1
JPH3 junctophilin 3
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6
KDM8 lysine (K)-specific demethylase 8
KIAA1024 KIAA1024
LINC00260 long intergenic non-protein coding RNA 260
LOC57399 uncharacterized gastric protein ZA52P
LTBP2 latent transforming growth factor beta binding protein 2
LY6D lymphocyte antigen 6 complex, locus D
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC6 mucin 6, oligomeric mucus/gel-forming
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYH4 myosin, heavy chain 4, skeletal muscle
MYL5 myosin, light chain 5, regulatory
NAT6 N-acetyltransferase 6 (GCN5-related)
NMUR1 neuromedin U receptor 1
ODF2 outer dense fiber of sperm tails 2
PCBP4 poly(rC) binding protein 4
PDE7B phosphodiesterase 7B
PFN2 profilin 2
PIP prolactin-induced protein
PIPOX pipecolic acid oxidase
PLA2G3 phospholipase A2, group III
PRR7 proline rich 7 (synaptic)
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
RAB3D RAB3D, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RBM12B-AS1 RBM12B antisense RNA 1
SALL2 spalt-like transcription factor 2
SCRT1 scratch family zinc finger 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SLC16A6 solute carrier family 16, member 6
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLITRK5 SLIT and NTRK-like family, member 5
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TIGD6 tigger transposable element derived 6
TMEM212 transmembrane protein 212
TNS2 tensin 2
TOM1 target of myb1 (chicken)
TRAF2 TNF receptor-associated factor 2
TTLL1 tubulin tyrosine ligase-like family member 1
UNC13A unc-13 homolog A (C. elegans)
VEGFB vascular endothelial growth factor B
WASF3 WAS protein family, member 3
ZNF280A zinc finger protein 280A
ZNF408 zinc finger protein 408
ZNF81 zinc finger protein 81
ZXDB zinc finger, X-linked, duplicated B