procyclidine-3330 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the procyclidine-3330 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AFF2 AF4/FMR2 family, member 2
AJAP1 adherens junctions associated protein 1
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BMP6 bone morphogenetic protein 6
C14ORF1 chromosome 14 open reading frame 1
C1ORF95 chromosome 1 open reading frame 95
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CD47 CD47 molecule
CD70 CD70 molecule
CEL carboxyl ester lipase
CES3 carboxylesterase 3
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal)
CLEC11A C-type lectin domain family 11, member A
CNTN5 contactin 5
CNTNAP2 contactin associated protein-like 2
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CPB1 carboxypeptidase B1 (tissue)
DFNB31 deafness, autosomal recessive 31
DMBT1 deleted in malignant brain tumors 1
DOCK9 dedicator of cytokinesis 9
ELSPBP1 epididymal sperm binding protein 1
FGF2 fibroblast growth factor 2 (basic)
FLJ42627 uncharacterized LOC645644
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
HAP1 huntingtin-associated protein 1
HIST1H2BJ histone cluster 1, H2bj
HOXA10 homeobox A10
HOXD11 homeobox D11
HR hair growth associated
ICAM5 intercellular adhesion molecule 5, telencephalin
IL12RB1 interleukin 12 receptor, beta 1
IL2RG interleukin 2 receptor, gamma
IPW imprinted in Prader-Willi syndrome (non-protein coding)
IRF8 interferon regulatory factor 8
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNIP1 Kv channel interacting protein 1
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
LDB3 LIM domain binding 3
LEPR leptin receptor
LINC00597 long intergenic non-protein coding RNA 597
LMF2 lipase maturation factor 2
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LTBP2 latent transforming growth factor beta binding protein 2
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MYF5 myogenic factor 5
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
PER1 period circadian clock 1
PKNOX2 PBX/knotted 1 homeobox 2
PLA2G1B phospholipase A2, group IB (pancreas)
PLP1 proteolipid protein 1
PLXNB3 plexin B3
PRKG2 protein kinase, cGMP-dependent, type II
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
REEP2 receptor accessory protein 2
RGS20 regulator of G-protein signaling 20
RIN3 Ras and Rab interactor 3
RND1 Rho family GTPase 1
RPS11 ribosomal protein S11
RUNDC3A RUN domain containing 3A
SDC2 syndecan 2
SH3BP2 SH3-domain binding protein 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC35E2 solute carrier family 35, member E2
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SOX3 SRY (sex determining region Y)-box 3
SPAG8 sperm associated antigen 8
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
TAC3 tachykinin 3
TAS2R1 taste receptor, type 2, member 1
TBXA2R thromboxane A2 receptor
TDRD3 tudor domain containing 3
TECPR2 tectonin beta-propeller repeat containing 2
TM4SF1 transmembrane 4 L six family member 1
TMEM176B transmembrane protein 176B
TMEM63A transmembrane protein 63A
TPMT thiopurine S-methyltransferase
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TRPM8 transient receptor potential cation channel, subfamily M, member 8
UCN urocortin
UMOD uromodulin
VN1R1 vomeronasal 1 receptor 1
WNT2B wingless-type MMTV integration site family, member 2B
ZC3H13 zinc finger CCCH-type containing 13
ZC3H7B zinc finger CCCH-type containing 7B
ZNF287 zinc finger protein 287
ZNF423 zinc finger protein 423
ZNF532 zinc finger protein 532
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ALPK1 alpha-kinase 1
ANP32A-IT1 ANP32A intronic transcript 1
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARMCX2 armadillo repeat containing, X-linked 2
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BAK1 BCL2-antagonist/killer 1
BMP4 bone morphogenetic protein 4
BPGM 2,3-bisphosphoglycerate mutase
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CCDC121 coiled-coil domain containing 121
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COPZ2 coatomer protein complex, subunit zeta 2
CTNNBIP1 catenin, beta interacting protein 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCAF16 DDB1 and CUL4 associated factor 16
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ELOVL4 ELOVL fatty acid elongase 4
ENO3 enolase 3 (beta, muscle)
EPHX2 epoxide hydrolase 2, cytoplasmic
ERCC4 excision repair cross-complementation group 4
F3 coagulation factor III (thromboplastin, tissue factor)
FAM46C family with sequence similarity 46, member C
FILIP1L filamin A interacting protein 1-like
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLRX glutaredoxin (thioltransferase)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HIST1H4F histone cluster 1, H4f
HOXA4 homeobox A4
IFT22 intraflagellar transport 22
IQSEC2 IQ motif and Sec7 domain 2
KCNK12 potassium channel, two pore domain subfamily K, member 12
KLF7 Kruppel-like factor 7 (ubiquitous)
KLHL25 kelch-like family member 25
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LRP2 low density lipoprotein receptor-related protein 2
LRRC37A3 leucine rich repeat containing 37, member A3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYRM9 LYR motif containing 9
LZTS3 leucine zipper, putative tumor suppressor family member 3
MBNL3 muscleblind-like splicing regulator 3
MBTD1 mbt domain containing 1
METTL8 methyltransferase like 8
MMP2 matrix metallopeptidase 2
MVD mevalonate (diphospho) decarboxylase
MYO1F myosin IF
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NPIPB3 nuclear pore complex interacting protein family, member B3
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OSMR oncostatin M receptor
PCDHGB5 protocadherin gamma subfamily B, 5
PHACTR4 phosphatase and actin regulator 4
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RAB3D RAB3D, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RPGRIP1L RPGRIP1-like
RUNDC3B RUN domain containing 3B
S100A2 S100 calcium binding protein A2
SETD1A SET domain containing 1A
SETD8 SET domain containing (lysine methyltransferase) 8
SFT2D2 SFT2 domain containing 2
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPRYD7 SPRY domain containing 7
STAG3 stromal antigen 3
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYBU syntabulin (syntaxin-interacting)
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMEM209 transmembrane protein 209
ULBP2 UL16 binding protein 2
VEGFB vascular endothelial growth factor B
VIPR1 vasoactive intestinal peptide receptor 1
WDR25 WD repeat domain 25
WDR33 WD repeat domain 33
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBTB44 zinc finger and BTB domain containing 44
ZBTB48 zinc finger and BTB domain containing 48
ZFHX2 zinc finger homeobox 2
ZNF329 zinc finger protein 329
ZNF586 zinc finger protein 586
ZNF652 zinc finger protein 652
ZNF669 zinc finger protein 669
ZNF721 zinc finger protein 721