| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the profenamine-3038 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| AMELX | amelogenin, X-linked |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) |
| ART4 | ADP-ribosyltransferase 4 (Dombrock blood group) |
| ATN1 | atrophin 1 |
| BMP7 | bone morphogenetic protein 7 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CAPN2 | calpain 2, (m/II) large subunit |
| CARD10 | caspase recruitment domain family, member 10 |
| CAV2 | caveolin 2 |
| CD248 | CD248 molecule, endosialin |
| CFAP70 | cilia and flagella associated protein 70 |
| CHRNA4 | cholinergic receptor, nicotinic, alpha 4 (neuronal) |
| CNPPD1 | cyclin Pas1/PHO80 domain containing 1 |
| COL17A1 | collagen, type XVII, alpha 1 |
| CPB1 | carboxypeptidase B1 (tissue) |
| CPZ | carboxypeptidase Z |
| CREBBP | CREB binding protein |
| CSN2 | casein beta |
| CSN3 | casein kappa |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DAGLA | diacylglycerol lipase, alpha |
| DLL3 | delta-like 3 (Drosophila) |
| DPYSL4 | dihydropyrimidinase-like 4 |
| EDDM3A | epididymal protein 3A |
| EFNA5 | ephrin-A5 |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FOXE1 | forkhead box E1 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| FZD10 | frizzled class receptor 10 |
| FZD4 | frizzled class receptor 4 |
| GABARAPL3 | GABA(A) receptors associated protein like 3, pseudogene |
| GPR157 | G protein-coupled receptor 157 |
| GTPBP1 | GTP binding protein 1 |
| GVINP1 | GTPase, very large interferon inducible pseudogene 1 |
| HEMK1 | HemK methyltransferase family member 1 |
| HFE | hemochromatosis |
| HOXB6 | homeobox B6 |
| HRASLS2 | HRAS-like suppressor 2 |
| IL2RA | interleukin 2 receptor, alpha |
| ITGB4 | integrin, beta 4 |
| KAT8 | K(lysine) acetyltransferase 8 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KIAA1045 | KIAA1045 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| MAP1A | microtubule-associated protein 1A |
| MBP | myelin basic protein |
| MCF2 | MCF.2 cell line derived transforming sequence |
| MPPE1 | metallophosphoesterase 1 |
| MTSS1 | metastasis suppressor 1 |
| MVD | mevalonate (diphospho) decarboxylase |
| MYH14 | myosin, heavy chain 14, non-muscle |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NCKAP1 | NCK-associated protein 1 |
| NES | nestin |
| NR1I2 | nuclear receptor subfamily 1, group I, member 2 |
| NRCAM | neuronal cell adhesion molecule |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme |
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha |
| PQBP1 | polyglutamine binding protein 1 |
| PRM2 | protamine 2 |
| PRO2964 | uncharacterized protein PRO2964 |
| PTGDR2 | prostaglandin D2 receptor 2 |
| PYY | peptide YY |
| RAB26 | RAB26, member RAS oncogene family |
| ROBO3 | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SCIN | scinderin |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SNPH | syntaphilin |
| SORBS2 | sorbin and SH3 domain containing 2 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| SYCP1 | synaptonemal complex protein 1 |
| TBX6 | T-box 6 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TLX3 | T-cell leukemia homeobox 3 |
| TRIM3 | tripartite motif containing 3 |
| TRO | trophinin |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 |
| UNC93A | unc-93 homolog A (C. elegans) |
| USH1C | Usher syndrome 1C (autosomal recessive, severe) |
| ZCCHC4 | zinc finger, CCHC domain containing 4 |
| ZNF407 | zinc finger protein 407 |
| Symbol | Name |
|---|---|
| ACOX2 | acyl-CoA oxidase 2, branched chain |
| ACPP | acid phosphatase, prostate |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A |
| AOAH | acyloxyacyl hydrolase (neutrophil) |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARL15 | ADP-ribosylation factor-like 15 |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CBLL1 | Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CELP | carboxyl ester lipase pseudogene |
| CEP295 | centrosomal protein 295kDa |
| CFP | complement factor properdin |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| DEF8 | differentially expressed in FDCP 8 homolog (mouse) |
| DOCK4 | dedicator of cytokinesis 4 |
| EDEM2 | ER degradation enhancer, mannosidase alpha-like 2 |
| EGR2 | early growth response 2 |
| FHL3 | four and a half LIM domains 3 |
| FLT4 | fms-related tyrosine kinase 4 |
| FOXD1 | forkhead box D1 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GIPC1 | GIPC PDZ domain containing family, member 1 |
| GLCE | glucuronic acid epimerase |
| GPATCH2L | G patch domain containing 2-like |
| GSDMD | gasdermin D |
| HHLA3 | HERV-H LTR-associating 3 |
| HIST1H1B | histone cluster 1, H1b |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AI | histone cluster 1, H2ai |
| HRAS | Harvey rat sarcoma viral oncogene homolog |
| IBSP | integrin-binding sialoprotein |
| IFI30 | interferon, gamma-inducible protein 30 |
| IFT81 | intraflagellar transport 81 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IL11RA | interleukin 11 receptor, alpha |
| KIAA0319L | KIAA0319-like |
| KIAA1107 | KIAA1107 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MTSS1L | metastasis suppressor 1-like |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NECAB3 | N-terminal EF-hand calcium binding protein 3 |
| NIPAL2 | NIPA-like domain containing 2 |
| NME8 | NME/NM23 family member 8 |
| NOL10 | nucleolar protein 10 |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PER3 | period circadian clock 3 |
| PIP4K2C | phosphatidylinositol-5-phosphate 4-kinase, type II, gamma |
| PRSS53 | protease, serine, 53 |
| PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| RARS | arginyl-tRNA synthetase |
| RBL1 | retinoblastoma-like 1 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RGS13 | regulator of G-protein signaling 13 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RIN2 | Ras and Rab interactor 2 |
| RPGRIP1L | RPGRIP1-like |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| SAV1 | salvador family WW domain containing protein 1 |
| SH3GLB2 | SH3-domain GRB2-like endophilin B2 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC35F5 | solute carrier family 35, member F5 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SNIP1 | Smad nuclear interacting protein 1 |
| SPATA20 | spermatogenesis associated 20 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 |
| TMEM120B | transmembrane protein 120B |
| TMEM19 | transmembrane protein 19 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TRPS1 | trichorhinophalangeal syndrome I |
| TUFT1 | tuftelin 1 |
| XAB2 | XPA binding protein 2 |
| YOD1 | YOD1 deubiquitinase |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZMAT3 | zinc finger, matrin-type 3 |
| ZNF354A | zinc finger protein 354A |
| ZNF768 | zinc finger protein 768 |