| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
195 genes differentially expressed following the profenamine-3376 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADRA1D | adrenoceptor alpha 1D |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ALDOAP2 | aldolase A, fructose-bisphosphate pseudogene 2 |
| AMPD1 | adenosine monophosphate deaminase 1 |
| ANGPTL2 | angiopoietin-like 2 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 |
| APOL3 | apolipoprotein L, 3 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ATF3 | activating transcription factor 3 |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 |
| CCDC71 | coiled-coil domain containing 71 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CD22 | CD22 molecule |
| CD300C | CD300c molecule |
| CD48 | CD48 molecule |
| CD53 | CD53 molecule |
| CD6 | CD6 molecule |
| CDHR1 | cadherin-related family member 1 |
| CHST3 | carbohydrate (chondroitin 6) sulfotransferase 3 |
| COL7A1 | collagen, type VII, alpha 1 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CRHR2 | corticotropin releasing hormone receptor 2 |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP11B1 | cytochrome P450, family 11, subfamily B, polypeptide 1 |
| CYP2A7 | cytochrome P450, family 2, subfamily A, polypeptide 7 |
| CYP3A7 | cytochrome P450, family 3, subfamily A, polypeptide 7 |
| CYTH4 | cytohesin 4 |
| DIO2 | deiodinase, iodothyronine, type II |
| DMWD | dystrophia myotonica, WD repeat containing |
| E2F5 | E2F transcription factor 5, p130-binding |
| EDA | ectodysplasin A |
| EFNB3 | ephrin-B3 |
| ERC2-IT1 | ERC2 intronic transcript 1 |
| F2RL3 | coagulation factor II (thrombin) receptor-like 3 |
| FBXO4 | F-box protein 4 |
| FGF17 | fibroblast growth factor 17 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type |
| GPR3 | G protein-coupled receptor 3 |
| GPSM3 | G-protein signaling modulator 3 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HEG1 | heart development protein with EGF-like domains 1 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IL17RC | interleukin 17 receptor C |
| INHBE | inhibin, beta E |
| ITGA7 | integrin, alpha 7 |
| KCNA6 | potassium channel, voltage gated shaker related subfamily A, member 6 |
| KIAA1456 | KIAA1456 |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| KLF2 | Kruppel-like factor 2 |
| KRT2 | keratin 2, type II |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LRRC17 | leucine rich repeat containing 17 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MBP | myelin basic protein |
| MNMIP1 | manchette microtubule inner protein 1 |
| MST1 | macrophage stimulating 1 |
| MT3 | metallothionein 3 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| NIPAL3 | NIPA-like domain containing 3 |
| NOV | nephroblastoma overexpressed |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NXPH3 | neurexophilin 3 |
| OR10J1 | olfactory receptor, family 10, subfamily J, member 1 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PENK | proenkephalin |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PGLYRP1 | peptidoglycan recognition protein 1 |
| PRM1 | protamine 1 |
| PTCRA | pre T-cell antigen receptor alpha |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RND2 | Rho family GTPase 2 |
| RPL35A | ribosomal protein L35a |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SPAG8 | sperm associated antigen 8 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SRRT | serrate, RNA effector molecule |
| SYT5 | synaptotagmin V |
| SZT2 | seizure threshold 2 homolog (mouse) |
| TAAR5 | trace amine associated receptor 5 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TNK2 | tyrosine kinase, non-receptor, 2 |
| VLDLR | very low density lipoprotein receptor |
| WSCD1 | WSC domain containing 1 |
| ZEB1 | zinc finger E-box binding homeobox 1 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARSB | arylsulfatase B |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C3 | complement component 3 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CCNK | cyclin K |
| CD82 | CD82 molecule |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CORO7 | coronin 7 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| DSC2 | desmocollin 2 |
| DYM | dymeclin |
| EDAR | ectodysplasin A receptor |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| FAM131A | family with sequence similarity 131, member A |
| FAM63A | family with sequence similarity 63, member A |
| FBXO2 | F-box protein 2 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| GPR143 | G protein-coupled receptor 143 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC7 | histone deacetylase 7 |
| HIST1H2BI | histone cluster 1, H2bi |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| INO80D | INO80 complex subunit D |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KLHL28 | kelch-like family member 28 |
| KRT83 | keratin 83, type II |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 |
| LIN7A | lin-7 homolog A (C. elegans) |
| MAGEA5 | melanoma antigen family A5 |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MANBA | mannosidase, beta A, lysosomal |
| MEFV | Mediterranean fever |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MMP2 | matrix metallopeptidase 2 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MSI1 | musashi RNA-binding protein 1 |
| MTL5 | metallothionein-like 5, testis-specific (tesmin) |
| NEUROD4 | neuronal differentiation 4 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NME5 | NME/NM23 family member 5 |
| NOL10 | nucleolar protein 10 |
| OLFML2A | olfactomedin-like 2A |
| PALM | paralemmin |
| PDIA3 | protein disulfide isomerase family A, member 3 |
| PRKCE | protein kinase C, epsilon |
| PTTG3P | pituitary tumor-transforming 3, pseudogene |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RCAN3 | RCAN family member 3 |
| RFPL1S | RFPL1 antisense RNA 1 |
| RGS20 | regulator of G-protein signaling 20 |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RIN1 | Ras and Rab interactor 1 |
| RND1 | Rho family GTPase 1 |
| SCARA3 | scavenger receptor class A, member 3 |
| SECTM1 | secreted and transmembrane 1 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SIRT2 | sirtuin 2 |
| SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
| SLC35E3 | solute carrier family 35, member E3 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC9A7 | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
| SPAG4 | sperm associated antigen 4 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| ST5 | suppression of tumorigenicity 5 |
| TBC1D2 | TBC1 domain family, member 2 |
| TBKBP1 | TBK1 binding protein 1 |
| TEP1 | telomerase-associated protein 1 |
| TEX40 | testis expressed 40 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TRIM68 | tripartite motif containing 68 |
| TSPYL2 | TSPY-like 2 |
| TUBA3C | tubulin, alpha 3c |
| TYRP1 | tyrosinase-related protein 1 |
| WDR62 | WD repeat domain 62 |
| XAB2 | XPA binding protein 2 |
| XYLT2 | xylosyltransferase II |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZFHX4 | zinc finger homeobox 4 |
| ZNF230 | zinc finger protein 230 |
| ZNF276 | zinc finger protein 276 |
| ZNF324 | zinc finger protein 324 |
| ZNF446 | zinc finger protein 446 |
| ZNF668 | zinc finger protein 668 |
| ZNF701 | zinc finger protein 701 |
| ZNF747 | zinc finger protein 747 |
| ZNF750 | zinc finger protein 750 |
