| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the profenamine-5296 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 |
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ABCD1 | ATP-binding cassette, sub-family D (ALD), member 1 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ALOX15 | arachidonate 15-lipoxygenase |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| ATF3 | activating transcription factor 3 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| ATP9A | ATPase, class II, type 9A |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| CCNG2 | cyclin G2 |
| CD22 | CD22 molecule |
| CDC25C | cell division cycle 25C |
| CDKN2AIP | CDKN2A interacting protein |
| CEP63 | centrosomal protein 63kDa |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DOC2A | double C2-like domains, alpha |
| DOCK1 | dedicator of cytokinesis 1 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EGR1 | early growth response 1 |
| EPHA1 | EPH receptor A1 |
| EPOR | erythropoietin receptor |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM102A | family with sequence similarity 102, member A |
| FAM155A | family with sequence similarity 155, member A |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GPC4 | glypican 4 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HDAC11 | histone deacetylase 11 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIST1H2BC | histone cluster 1, H2bc |
| HOXC10 | homeobox C10 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| ING1 | inhibitor of growth family, member 1 |
| ING4 | inhibitor of growth family, member 4 |
| INHBE | inhibin, beta E |
| IQCK | IQ motif containing K |
| JRK | Jrk homolog (mouse) |
| KLHL24 | kelch-like family member 24 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LOC399491 | |
| LSM4 | LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MMP19 | matrix metallopeptidase 19 |
| MPPE1 | metallophosphoesterase 1 |
| NDUFB8 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa |
| NEK1 | NIMA-related kinase 1 |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLK4 | polo-like kinase 4 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PODXL2 | podocalyxin-like 2 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| QPCT | glutaminyl-peptide cyclotransferase |
| RAB17 | RAB17, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RANBP1 | RAN binding protein 1 |
| RNF19B | ring finger protein 19B |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| RPL10 | ribosomal protein L10 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| S100A4 | S100 calcium binding protein A4 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SGPL1 | sphingosine-1-phosphate lyase 1 |
| SGSM3 | small G protein signaling modulator 3 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SPATA5L1 | spermatogenesis associated 5-like 1 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| TLE3 | transducin-like enhancer of split 3 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TSC22D3 | TSC22 domain family, member 3 |
| TTC9 | tetratricopeptide repeat domain 9 |
| USP34 | ubiquitin specific peptidase 34 |
| VCPIP1 | valosin containing protein (p97)/p47 complex interacting protein 1 |
| VEGFA | vascular endothelial growth factor A |
| ZNF24 | zinc finger protein 24 |
| Symbol | Name |
|---|---|
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| ALPK1 | alpha-kinase 1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APH1A | APH1A gamma secretase subunit |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| BAX | BCL2-associated X protein |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| BTBD2 | BTB (POZ) domain containing 2 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CAMTA1 | calmodulin binding transcription activator 1 |
| CAMTA2 | calmodulin binding transcription activator 2 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CASZ1 | castor zinc finger 1 |
| CCNE1 | cyclin E1 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CHMP7 | charged multivesicular body protein 7 |
| CSNK1E | casein kinase 1, epsilon |
| CTC1 | CTS telomere maintenance complex component 1 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CTSK | cathepsin K |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DVL1 | dishevelled segment polarity protein 1 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| ELMO3 | engulfment and cell motility 3 |
| ERCC3 | excision repair cross-complementation group 3 |
| ERCC5 | excision repair cross-complementation group 5 |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FAM50B | family with sequence similarity 50, member B |
| FAM63A | family with sequence similarity 63, member A |
| FBXO46 | F-box protein 46 |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FXR2 | fragile X mental retardation, autosomal homolog 2 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIRA | histone cell cycle regulator |
| HIST1H1D | histone cluster 1, H1d |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| IREB2 | iron-responsive element binding protein 2 |
| KIF13B | kinesin family member 13B |
| KIFC1 | kinesin family member C1 |
| KRBOX4 | KRAB box domain containing 4 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LMNB1 | lamin B1 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LOC730101 | uncharacterized LOC730101 |
| LOXL1 | lysyl oxidase-like 1 |
| LRRC16A | leucine rich repeat containing 16A |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 |
| MED9 | mediator complex subunit 9 |
| MRPL2 | mitochondrial ribosomal protein L2 |
| MT1E | metallothionein 1E |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYO1D | myosin ID |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| OSMR | oncostatin M receptor |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PARD6A | par-6 family cell polarity regulator alpha |
| PGS1 | phosphatidylglycerophosphate synthase 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| RECQL4 | RecQ protein-like 4 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RWDD3 | RWD domain containing 3 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SPAG4 | sperm associated antigen 4 |
| SPIDR | scaffolding protein involved in DNA repair |
| STK16 | serine/threonine kinase 16 |
| TAF5L | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TARS2 | threonyl-tRNA synthetase 2, mitochondrial (putative) |
| TDRD1 | tudor domain containing 1 |
| TGFB3 | transforming growth factor, beta 3 |
| TMC7 | transmembrane channel-like 7 |
| TMEM127 | transmembrane protein 127 |
| TMEM159 | transmembrane protein 159 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TPCN1 | two pore segment channel 1 |
| VGF | VGF nerve growth factor inducible |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR76 | WD repeat domain 76 |
| WWC2 | WW and C2 domain containing 2 |
| XYLT2 | xylosyltransferase II |
| ZNF14 | zinc finger protein 14 |
| ZNF282 | zinc finger protein 282 |
| ZNF557 | zinc finger protein 557 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNF778 | zinc finger protein 778 |
| ZNF8 | zinc finger protein 8 |
