| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the profenamine-6697 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAA2 | acetyl-CoA acyltransferase 2 |
| ACOT11 | acyl-CoA thioesterase 11 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| APAF1 | apoptotic peptidase activating factor 1 |
| APC | adenomatous polyposis coli |
| AQP4 | aquaporin 4 |
| ARHGAP28 | Rho GTPase activating protein 28 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C8A | complement component 8, alpha polypeptide |
| CANX | calnexin |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CBS | cystathionine-beta-synthase |
| CD1C | CD1c molecule |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CLCN4 | chloride channel, voltage-sensitive 4 |
| CLDN1 | claudin 1 |
| COPE | coatomer protein complex, subunit epsilon |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL5 | chemokine (C-X-C motif) ligand 5 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DCLK2 | doublecortin-like kinase 2 |
| DDO | D-aspartate oxidase |
| DENND3 | DENN/MADD domain containing 3 |
| DIO2 | deiodinase, iodothyronine, type II |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| FGF5 | fibroblast growth factor 5 |
| FLT3LG | fms-related tyrosine kinase 3 ligand |
| FRMD4B | FERM domain containing 4B |
| GPR176 | G protein-coupled receptor 176 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B |
| GPX3 | glutathione peroxidase 3 |
| HFE | hemochromatosis |
| ICAM1 | intercellular adhesion molecule 1 |
| IFFO1 | intermediate filament family orphan 1 |
| IL1B | interleukin 1, beta |
| IL23A | interleukin 23, alpha subunit p19 |
| IL6 | interleukin 6 |
| IL7R | interleukin 7 receptor |
| INHBA | inhibin, beta A |
| INSIG1 | insulin induced gene 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KIAA0391 | KIAA0391 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KRT37 | keratin 37, type I |
| KYNU | kynureninase |
| LAMC2 | laminin, gamma 2 |
| LIPG | lipase, endothelial |
| LOXL3 | lysyl oxidase-like 3 |
| LRRC37A4P | leucine rich repeat containing 37, member A4, pseudogene |
| LRRN3 | leucine rich repeat neuronal 3 |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MLXIP | MLX interacting protein |
| MMP13 | matrix metallopeptidase 13 |
| MRC2 | mannose receptor, C type 2 |
| MYBPC3 | myosin binding protein C, cardiac |
| NCOR2 | nuclear receptor corepressor 2 |
| NF2 | neurofibromin 2 (merlin) |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NNAT | neuronatin |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
| PTAFR | platelet-activating factor receptor |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPN22 | protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| SAMD4A | sterile alpha motif domain containing 4A |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SRRT | serrate, RNA effector molecule |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TGFB2 | transforming growth factor, beta 2 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNIP1 | TNFAIP3 interacting protein 1 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| TUBA3C | tubulin, alpha 3c |
| UGCG | UDP-glucose ceramide glucosyltransferase |
| VCAN | versican |
| WDR78 | WD repeat domain 78 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF24 | zinc finger protein 24 |
| ZNF500 | zinc finger protein 500 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| ABCA3 | ATP-binding cassette, sub-family A (ABC1), member 3 |
| AMT | aminomethyltransferase |
| ARL14 | ADP-ribosylation factor-like 14 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C19ORF54 | chromosome 19 open reading frame 54 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase |
| CCP110 | centriolar coiled coil protein 110kDa |
| CEL | carboxyl ester lipase |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DENND1B | DENN/MADD domain containing 1B |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
| ENDOG | endonuclease G |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FAM186A | family with sequence similarity 186, member A |
| FANCL | Fanconi anemia, complementation group L |
| FGF13 | fibroblast growth factor 13 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FLT4 | fms-related tyrosine kinase 4 |
| GALK1 | galactokinase 1 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GMPR | guanosine monophosphate reductase |
| GPNMB | glycoprotein (transmembrane) nmb |
| GRAMD1C | GRAM domain containing 1C |
| GRAMD4 | GRAM domain containing 4 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H3A | histone cluster 1, H3a |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HOXA1 | homeobox A1 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| IFT22 | intraflagellar transport 22 |
| IL36RN | interleukin 36 receptor antagonist |
| INCENP | inner centromere protein antigens 135/155kDa |
| KIAA1456 | KIAA1456 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LOC100287590 | uncharacterized LOC100287590 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MXD3 | MAX dimerization protein 3 |
| MYO1F | myosin IF |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NARFL | nuclear prelamin A recognition factor-like |
| NCS1 | neuronal calcium sensor 1 |
| NDP | Norrie disease (pseudoglioma) |
| NOL12 | nucleolar protein 12 |
| NRTN | neurturin |
| NSUN6 | NOP2/Sun domain family, member 6 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PRF1 | perforin 1 (pore forming protein) |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RWDD3 | RWD domain containing 3 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SMA4 | glucuronidase, beta pseudogene |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TENM4 | teneurin transmembrane protein 4 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TUBB2B | tubulin, beta 2B class IIb |
| USP18 | ubiquitin specific peptidase 18 |
| WDR62 | WD repeat domain 62 |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZFYVE16 | zinc finger, FYVE domain containing 16 |
| ZNF408 | zinc finger protein 408 |
| ZNF529 | zinc finger protein 529 |
| ZNF552 | zinc finger protein 552 |
| ZNF702P | zinc finger protein 702, pseudogene |
| ZNF770 | zinc finger protein 770 |
| ZNF816 | zinc finger protein 816 |
