profibrotic Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

82 genes co-occuring with the biological term profibrotic in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACE2 angiotensin I converting enzyme 2
ADORA2A adenosine A2a receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ARID3A AT rich interactive domain 3A (BRIGHT-like)
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMP7 bone morphogenetic protein 7
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCR2 chemokine (C-C motif) receptor 2
CD40LG CD40 ligand
CNR1 cannabinoid receptor 1 (brain)
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CSF1 colony stimulating factor 1 (macrophage)
CTGF connective tissue growth factor
DOK5 docking protein 5
EDN1 endothelin 1
EGR3 early growth response 3
F2R coagulation factor II (thrombin) receptor
FBN1 fibrillin 1
FGF2 fibroblast growth factor 2 (basic)
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FOSL1 FOS-like antigen 1
FOSL2 FOS-like antigen 2
FOXF1 forkhead box F1
GREM1 gremlin 1, DAN family BMP antagonist
GSK3A glycogen synthase kinase 3 alpha
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGFBP5 insulin-like growth factor binding protein 5
IL13 interleukin 13
IL17A interleukin 17A
IL18 interleukin 18
IL34 interleukin 34
IL4 interleukin 4
ITGA11 integrin, alpha 11
JUN jun proto-oncogene
KNG1 kininogen 1
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MIR150 microRNA 150
MMP1 matrix metallopeptidase 1
MSR1 macrophage scavenger receptor 1
NOV nephroblastoma overexpressed
NOX4 NADPH oxidase 4
NR1I3 nuclear receptor subfamily 1, group I, member 3
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
POSTN periostin, osteoblast specific factor
PPARG peroxisome proliferator-activated receptor gamma
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCD protein kinase C, delta
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTK2 protein tyrosine kinase 2
REN renin
RGCC regulator of cell cycle
RHOA ras homolog family member A
RXFP1 relaxin/insulin-like family peptide receptor 1
S100A9 S100 calcium binding protein A9
S1PR2 sphingosine-1-phosphate receptor 2
S1PR3 sphingosine-1-phosphate receptor 3
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SMAD1 SMAD family member 1
SMAD3 SMAD family member 3
SOCS1 suppressor of cytokine signaling 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPP1 secreted phosphoprotein 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TGFB1 transforming growth factor, beta 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGFBR1 transforming growth factor, beta receptor 1
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TLR4 toll-like receptor 4
TLR8 toll-like receptor 8
TP53 tumor protein p53
TSLP thymic stromal lymphopoietin
VEGFA vascular endothelial growth factor A