progesterone-2426 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the progesterone-2426 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADD2 adducin 2 (beta)
ADGRG3 adhesion G protein-coupled receptor G3
ALOX5 arachidonate 5-lipoxygenase
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
B9D1 B9 protein domain 1
BMP8B bone morphogenetic protein 8b
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C17ORF59 chromosome 17 open reading frame 59
CCDC33 coiled-coil domain containing 33
CD44 CD44 molecule (Indian blood group)
CDC42 cell division cycle 42
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CLCA1 chloride channel accessory 1
COL4A2 collagen, type IV, alpha 2
CSF1 colony stimulating factor 1 (macrophage)
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
DHRS12 dehydrogenase/reductase (SDR family) member 12
DRD2 dopamine receptor D2
DTNB dystrobrevin, beta
EED embryonic ectoderm development
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
EPS8L1 EPS8-like 1
ESRRA estrogen-related receptor alpha
EWSR1 EWS RNA-binding protein 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP3 fatty acid binding protein 3, muscle and heart
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FKBP14 FK506 binding protein 14, 22 kDa
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GEMIN7 gem (nuclear organelle) associated protein 7
GJA9 gap junction protein, alpha 9, 59kDa
GPR153 G protein-coupled receptor 153
GRSF1 G-rich RNA sequence binding factor 1
HFE hemochromatosis
HNRNPF heterogeneous nuclear ribonucleoprotein F
HOMER2 homer scaffolding protein 2
HOXA10 homeobox A10
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IL1RAP interleukin 1 receptor accessory protein
IL24 interleukin 24
IL5RA interleukin 5 receptor, alpha
INCENP inner centromere protein antigens 135/155kDa
INO80B INO80 complex subunit B
KIF1A kinesin family member 1A
KLF3 Kruppel-like factor 3 (basic)
KYNU kynureninase
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
LPPR1 lipid phosphate phosphatase-related protein type 1
LRRC41 leucine rich repeat containing 41
MAGEB3 melanoma antigen family B3
MAL mal, T-cell differentiation protein
MAOA monoamine oxidase A
MAPK14 mitogen-activated protein kinase 14
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MATN1 matrilin 1, cartilage matrix protein
MDFIC MyoD family inhibitor domain containing
MPDZ multiple PDZ domain protein
MRC2 mannose receptor, C type 2
MYL10 myosin, light chain 10, regulatory
NEURL1 neuralized E3 ubiquitin protein ligase 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDPN podoplanin
PRAMEF10 PRAME family member 10
PTPRK protein tyrosine phosphatase, receptor type, K
PURG purine-rich element binding protein G
RAB13 RAB13, member RAS oncogene family
RASAL2 RAS protein activator like 2
RPH3A rabphilin 3A
S100A13 S100 calcium binding protein A13
SCAMP5 secretory carrier membrane protein 5
SCUBE2 signal peptide, CUB domain, EGF-like 2
SDS serine dehydratase
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC16A4 solute carrier family 16, member 4
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SPDEF SAM pointed domain containing ETS transcription factor
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TBX2 T-box 2
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TFF2 trefoil factor 2
THBS1 thrombospondin 1
TJP1 tight junction protein 1
TLR8 toll-like receptor 8
TMPRSS6 transmembrane protease, serine 6
TP53I11 tumor protein p53 inducible protein 11
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZCCHC11 zinc finger, CCHC domain containing 11
ZMYND8 zinc finger, MYND-type containing 8

decreased expression

Symbol Name
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ARG1 arginase 1
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ATF3 activating transcription factor 3
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
BRAF B-Raf proto-oncogene, serine/threonine kinase
C7ORF43 chromosome 7 open reading frame 43
CD1D CD1d molecule
CD69 CD69 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEL carboxyl ester lipase
CENPT centromere protein T
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLGN calmegin
COL9A2 collagen, type IX, alpha 2
CX3CR1 chemokine (C-X3-C motif) receptor 1
CYTIP cytohesin 1 interacting protein
DHRS3 dehydrogenase/reductase (SDR family) member 3
DKK2 dickkopf WNT signaling pathway inhibitor 2
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EGLN1 egl-9 family hypoxia-inducible factor 1
ENO2 enolase 2 (gamma, neuronal)
FAM102A family with sequence similarity 102, member A
FAM204A family with sequence similarity 204, member A
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FGF23 fibroblast growth factor 23
FGL1 fibrinogen-like 1
FKBP9 FK506 binding protein 9, 63 kDa
FOXD1 forkhead box D1
GAA glucosidase, alpha; acid
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPNMB glycoprotein (transmembrane) nmb
GPRC5C G protein-coupled receptor, class C, group 5, member C
GYS1 glycogen synthase 1 (muscle)
HDAC9 histone deacetylase 9
HILPDA hypoxia inducible lipid droplet-associated
HP haptoglobin
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
KDM3A lysine (K)-specific demethylase 3A
LIMD2 LIM domain containing 2
LIME1 Lck interacting transmembrane adaptor 1
LIN7B lin-7 homolog B (C. elegans)
MAGEH1 melanoma antigen family H1
MEGF8 multiple EGF-like-domains 8
MIR22HG MIR22 host gene
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NCKAP1L NCK-associated protein 1-like
NDE1 nudE neurodevelopment protein 1
NDRG1 N-myc downstream regulated 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NSUN6 NOP2/Sun domain family, member 6
NTSR1 neurotensin receptor 1 (high affinity)
OCEL1 occludin/ELL domain containing 1
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OVGP1 oviductal glycoprotein 1, 120kDa
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PARP16 poly (ADP-ribose) polymerase family, member 16
PDGFD platelet derived growth factor D
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PHACTR1 phosphatase and actin regulator 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PNOC prepronociceptin
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PRKCZ protein kinase C, zeta
PTDSS2 phosphatidylserine synthase 2
RGS13 regulator of G-protein signaling 13
RGS2 regulator of G-protein signaling 2
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOBTB2 Rho-related BTB domain containing 2
RLF rearranged L-myc fusion
SCG5 secretogranin V
SETD1A SET domain containing 1A
SIDT1 SID1 transmembrane family, member 1
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPP1 secreted phosphoprotein 1
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THBS3 thrombospondin 3
TICAM1 toll-like receptor adaptor molecule 1
TIMP2 TIMP metallopeptidase inhibitor 2
TMEM45A transmembrane protein 45A
TRAF1 TNF receptor-associated factor 1
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TRIM36 tripartite motif containing 36
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TTLL1 tubulin tyrosine ligase-like family member 1
UCN urocortin
UNC13B unc-13 homolog B (C. elegans)
VGLL4 vestigial-like family member 4
ZNF395 zinc finger protein 395
ZNF552 zinc finger protein 552
ZNF747 zinc finger protein 747