progesterone-4992 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the progesterone-4992 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAN aggrecan
ADAM19 ADAM metallopeptidase domain 19
ADAM22 ADAM metallopeptidase domain 22
AGRN agrin
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BAIAP3 BAI1-associated protein 3
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BTN3A1 butyrophilin, subfamily 3, member A1
BTNL3 butyrophilin-like 3
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAPN9 calpain 9
CCKAR cholecystokinin A receptor
CD177 CD177 molecule
CDC14B cell division cycle 14B
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHN2 chimerin 2
CNN1 calponin 1, basic, smooth muscle
COL6A1 collagen, type VI, alpha 1
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CROCC ciliary rootlet coiled-coil, rootletin
DLK2 delta-like 2 homolog (Drosophila)
DPY19L1P1 DPY19L1 pseudogene 1
DUOX1 dual oxidase 1
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
F13A1 coagulation factor XIII, A1 polypeptide
FBN2 fibrillin 2
FBXO41 F-box protein 41
FMO5 flavin containing monooxygenase 5
FSCN3 fascin actin-bundling protein 3, testicular
FYB FYN binding protein
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GFI1 growth factor independent 1 transcription repressor
GJA4 gap junction protein, alpha 4, 37kDa
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GPR39 G protein-coupled receptor 39
GPRC5B G protein-coupled receptor, class C, group 5, member B
GRIP2 glutamate receptor interacting protein 2
GSK3A glycogen synthase kinase 3 alpha
GSTP1 glutathione S-transferase pi 1
GSTTP1 glutathione S-transferase theta pseudogene 1
GZMK granzyme K (granzyme 3; tryptase II)
HAS1 hyaluronan synthase 1
HDLBP high density lipoprotein binding protein
HIST1H1T histone cluster 1, H1t
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene)
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL36R interleukin 36 receptor
IRF9 interferon regulatory factor 9
ITGB4 integrin, beta 4
KANK1 KN motif and ankyrin repeat domains 1
KDM4B lysine (K)-specific demethylase 4B
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KLF9 Kruppel-like factor 9
KMT2A lysine (K)-specific methyltransferase 2A
KRT19P2 keratin 19 pseudogene 2
LEPR leptin receptor
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAP1A microtubule-associated protein 1A
MAPKBP1 mitogen-activated protein kinase binding protein 1
MFAP5 microfibrillar associated protein 5
MKL1 megakaryoblastic leukemia (translocation) 1
MORC1 MORC family CW-type zinc finger 1
NEURL1 neuralized E3 ubiquitin protein ligase 1
NOP16 NOP16 nucleolar protein
NOVA2 neuro-oncological ventral antigen 2
NPAS3 neuronal PAS domain protein 3
NR2E3 nuclear receptor subfamily 2, group E, member 3
NT5M 5',3'-nucleotidase, mitochondrial
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
ORM1 orosomucoid 1
PEG10 paternally expressed 10
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRDM14 PR domain containing 14
RNF126P1 ring finger protein 126 pseudogene 1
S100A13 S100 calcium binding protein A13
SCAND2P SCAN domain containing 2 pseudogene
SLC43A3 solute carrier family 43, member 3
STC1 stanniocalcin 1
THAP3 THAP domain containing, apoptosis associated protein 3
THRB thyroid hormone receptor, beta
TLR5 toll-like receptor 5
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1
TRIM15 tripartite motif containing 15
TRIM29 tripartite motif containing 29
TRIM31 tripartite motif containing 31
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TTC9 tetratricopeptide repeat domain 9
TUBA3C tubulin, alpha 3c
WDTC1 WD and tetratricopeptide repeats 1
WSCD1 WSC domain containing 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
ACSL4 acyl-CoA synthetase long-chain family member 4
ACTG2 actin, gamma 2, smooth muscle, enteric
ADCY6 adenylate cyclase 6
ADGRE5 adhesion G protein-coupled receptor E5
AGBL5 ATP/GTP binding protein-like 5
AKAP12 A kinase (PRKA) anchor protein 12
APOD apolipoprotein D
ARHGAP10 Rho GTPase activating protein 10
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ATAD5 ATPase family, AAA domain containing 5
ATG9A autophagy related 9A
AUH AU RNA binding protein/enoyl-CoA hydratase
BBC3 BCL2 binding component 3
BCL7C B-cell CLL/lymphoma 7C
BCL9 B-cell CLL/lymphoma 9
C1ORF115 chromosome 1 open reading frame 115
CASD1 CAS1 domain containing 1
CCDC186 coiled-coil domain containing 186
CD302 CD302 molecule
CENPJ centromere protein J
CHKB choline kinase beta
CHMP6 charged multivesicular body protein 6
CHRM3 cholinergic receptor, muscarinic 3
CLCF1 cardiotrophin-like cytokine factor 1
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
COBL cordon-bleu WH2 repeat protein
COCH cochlin
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DEAF1 DEAF1 transcription factor
DHRS3 dehydrogenase/reductase (SDR family) member 3
DOCK1 dedicator of cytokinesis 1
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
ERCC3 excision repair cross-complementation group 3
FAAH fatty acid amide hydrolase
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FER fer (fps/fes related) tyrosine kinase
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FSD1 fibronectin type III and SPRY domain containing 1
GLI3 GLI family zinc finger 3
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
HAUS6 HAUS augmin-like complex, subunit 6
HP1BP3 heterochromatin protein 1, binding protein 3
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
KLHL26 kelch-like family member 26
LYPD1 LY6/PLAUR domain containing 1
MALL mal, T-cell differentiation protein-like
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MNX1 motor neuron and pancreas homeobox 1
MRPL2 mitochondrial ribosomal protein L2
N4BP3 NEDD4 binding protein 3
NDE1 nudE neurodevelopment protein 1
NFE2L3 nuclear factor, erythroid 2-like 3
P3H1 prolyl 3-hydroxylase 1
PACS1 phosphofurin acidic cluster sorting protein 1
PARD6A par-6 family cell polarity regulator alpha
PARPBP PARP1 binding protein
PGBD5 piggyBac transposable element derived 5
PHC1 polyhomeotic homolog 1 (Drosophila)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POMT2 protein-O-mannosyltransferase 2
PRPH peripherin
PTK6 protein tyrosine kinase 6
PVRL3 poliovirus receptor-related 3
QSER1 glutamine and serine rich 1
RAB3A RAB3A, member RAS oncogene family
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RFTN1 raftlin, lipid raft linker 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF123 ring finger protein 123
RPAP1 RNA polymerase II associated protein 1
RPGRIP1L RPGRIP1-like
SCAI suppressor of cancer cell invasion
SCRN3 secernin 3
SF3A3 splicing factor 3a, subunit 3, 60kDa
SHARPIN SHANK-associated RH domain interactor
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STAG3L1 stromal antigen 3-like 1 (pseudogene)
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
THBS3 thrombospondin 3
TMEM183A transmembrane protein 183A
TTC33 tetratricopeptide repeat domain 33
URGCP upregulator of cell proliferation
WDR91 WD repeat domain 91
ZBTB39 zinc finger and BTB domain containing 39
ZNF322P1 zinc finger protein 322 pseudogene 1
ZNF350 zinc finger protein 350
ZNF468 zinc finger protein 468
ZNF668 zinc finger protein 668
ZNF696 zinc finger protein 696
ZNF787 zinc finger protein 787
ZW10 zw10 kinetochore protein