progesterone Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A C21-steroid hormone in which a pregnane skeleton carries oxo substituents at positions 3 and 20 and is unsaturated at C(4)-C(5). As a hormone, it is involved in the female menstrual cycle, pregnancy and embryogenesis of humans and other species. (Chemical Entities of Biological Interest Ontology, CHEBI_17026)
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Genes

280 genes co-occuring with the biological term progesterone in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ADA adenosine deaminase
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ADIPOQ adiponectin, C1Q and collagen domain containing
AHSP alpha hemoglobin stabilizing protein
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
AKR1C4 aldo-keto reductase family 1, member C4
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANXA4 annexin A4
AR androgen receptor
ATM ATM serine/threonine kinase
AURKA aurora kinase A
AURKB aurora kinase B
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMP15 bone morphogenetic protein 15
BMP4 bone morphogenetic protein 4
BMPR1A bone morphogenetic protein receptor, type IA
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BSG basigin (Ok blood group)
C10ORF10 chromosome 10 open reading frame 10
C3 complement component 3
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CALB2 calbindin 2
CALCA calcitonin-related polypeptide alpha
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CATSPER1 cation channel, sperm associated 1
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CCNA2 cyclin A2
CCNB1 cyclin B1
CCND1 cyclin D1
CCNG1 cyclin G1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD151 CD151 molecule (Raph blood group)
CD1A CD1a molecule
CDK2 cyclin-dependent kinase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CGA glycoprotein hormones, alpha polypeptide
CGB chorionic gonadotropin, beta polypeptide
CHEK1 checkpoint kinase 1
CLDN3 claudin 3
CLDN4 claudin 4
CNR1 cannabinoid receptor 1 (brain)
CRH corticotropin releasing hormone
CRHR2 corticotropin releasing hormone receptor 2
CRP C-reactive protein, pentraxin-related
CSN2 casein beta
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CST6 cystatin E/M
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSB cathepsin B
CTSL cathepsin L
CUEDC2 CUE domain containing 2
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP4X1 cytochrome P450, family 4, subfamily X, polypeptide 1
CYP4Z1 cytochrome P450, family 4, subfamily Z, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DEFB4A defensin, beta 4A
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
E2F1 E2F transcription factor 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
FAAH fatty acid amide hydrolase
FBLN1 fibulin 1
FGF2 fibroblast growth factor 2 (basic)
FGF4 fibroblast growth factor 4
FGF8 fibroblast growth factor 8 (androgen-induced)
FGFR2 fibroblast growth factor receptor 2
FGR FGR proto-oncogene, Src family tyrosine kinase
FKBP5 FK506 binding protein 5
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXO1 forkhead box O1
FSHB follicle stimulating hormone, beta polypeptide
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA3 GATA binding protein 3
GDF9 growth differentiation factor 9
GH1 growth hormone 1
GJA1 gap junction protein, alpha 1, 43kDa
GLO1 glyoxalase I
GLRA1 glycine receptor, alpha 1
GLRB glycine receptor, beta
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GNRH2 gonadotropin-releasing hormone 2
GPER1 G protein-coupled estrogen receptor 1
GSK3B glycogen synthase kinase 3 beta
GSTP1 glutathione S-transferase pi 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLA-C major histocompatibility complex, class I, C
HLA-E major histocompatibility complex, class I, E
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
HNF4A hepatocyte nuclear factor 4, alpha
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HTRA3 HtrA serine peptidase 3
IDO1 indoleamine 2,3-dioxygenase 1
IFITM3 interferon induced transmembrane protein 3
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP1 insulin-like growth factor binding protein 1
IGFBP3 insulin-like growth factor binding protein 3
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL17A interleukin 17A
IL1B interleukin 1, beta
IL27 interleukin 27
IL6 interleukin 6
INHA inhibin, alpha
INHBA inhibin, beta A
IRS1 insulin receptor substrate 1
IRS2 insulin receptor substrate 2
ITGA1 integrin, alpha 1
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JDP2 Jun dimerization protein 2
JUN jun proto-oncogene
KAT7 K(lysine) acetyltransferase 7
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KDM5A lysine (K)-specific demethylase 5A
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF11 Kruppel-like factor 11
KLF13 Kruppel-like factor 13
KLF4 Kruppel-like factor 4 (gut)
KLF9 Kruppel-like factor 9
KLK14 kallikrein-related peptidase 14
LEP leptin
LEPR leptin receptor
LGALS3 lectin, galactoside-binding, soluble, 3
LHB luteinizing hormone beta polypeptide
MACROD1 MACRO domain containing 1
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MATK megakaryocyte-associated tyrosine kinase
MECP2 methyl CpG binding protein 2
MIR155 microRNA 155
MIR15A microRNA 15a
MIR200A microRNA 200a
MKI67 marker of proliferation Ki-67
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MSI1 musashi RNA-binding protein 1
MUC1 mucin 1, cell surface associated
MYD88 myeloid differentiation primary response 88
NCOA1 nuclear receptor coactivator 1
NCOR2 nuclear receptor corepressor 2
NCR3 natural cytotoxicity triggering receptor 3
NF1 neurofibromin 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NONO non-POU domain containing, octamer-binding
NOS2 nitric oxide synthase 2, inducible
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR3C2 nuclear receptor subfamily 3, group C, member 2
NR5A1 nuclear receptor subfamily 5, group A, member 1
NR5A2 nuclear receptor subfamily 5, group A, member 2
OXTR oxytocin receptor
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PAQR5 progestin and adipoQ receptor family member V
PAQR6 progestin and adipoQ receptor family member VI
PAQR7 progestin and adipoQ receptor family member VII
PAQR8 progestin and adipoQ receptor family member VIII
PAQR9 progestin and adipoQ receptor family member IX
PAWR PRKC, apoptosis, WT1, regulator
PCNA proliferating cell nuclear antigen
PEBP4 phosphatidylethanolamine-binding protein 4
PGR progesterone receptor
PGRMC1 progesterone receptor membrane component 1
PIAS4 protein inhibitor of activated STAT, 4
PIBF1 progesterone immunomodulatory binding factor 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
POMC proopiomelanocortin
PPARA peroxisome proliferator-activated receptor alpha
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRL prolactin
PRLR prolactin receptor
PROS1 protein S (alpha)
PTEN phosphatase and tensin homolog
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTX3 pentraxin 3, long
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RETN resistin
RHOBTB2 Rho-related BTB domain containing 2
SCARB1 scavenger receptor class B, member 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SDC1 syndecan 1
SDC4 syndecan 4
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SFN stratifin
SFPQ splicing factor proline/glutamine-rich
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC22A9 solute carrier family 22 (organic anion transporter), member 9
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SLPI secretory leukocyte peptidase inhibitor
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SP1 Sp1 transcription factor
SRA1 steroid receptor RNA activator 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRD5A1 steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
STAR steroidogenic acute regulatory protein
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STC1 stanniocalcin 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TAC1 tachykinin, precursor 1
TCL1B T-cell leukemia/lymphoma 1B
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1 transforming growth factor, beta 1
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TGM2 transglutaminase 2
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TP53 tumor protein p53
TRERF1 transcriptional regulating factor 1
TRIM25 tripartite motif containing 25
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TYMP thymidine phosphorylase
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UCN3 urocortin 3
UNC45A unc-45 homolog A (C. elegans)
VEGFA vascular endothelial growth factor A
WBP2 WW domain binding protein 2
WT1 Wilms tumor 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
YAP1 Yes-associated protein 1